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J-GLOBAL ID：201702290248716519   Reference number：17A1956522

A New Electron Microscopic Method to Observe the Distribution of Phosphatidylinositol 3,4-bisphosphate

ホスファチジルイノシトール3,4-ビスホスフェートの分布を観察するための新しい電子顕微鏡法

Author (8)： Aktar Sharmin (Department of Anatomy and Molecular Cell Biology, Nagoya University Graduate School of Medicine) ,  Takatori Sho (Department of Anatomy and Molecular Cell Biology, Nagoya University Graduate School of Medicine) ,  Takatori Sho (Present affiliation: Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo) ,  Tsuji Takuma (Department of Anatomy and Molecular Cell Biology, Nagoya University Graduate School of Medicine) ,  Orii Minami (Department of Anatomy and Molecular Cell Biology, Nagoya University Graduate School of Medicine) ,  Ohsaki Yuki (Department of Anatomy and Molecular Cell Biology, Nagoya University Graduate School of Medicine) ,  Cheng Jinglei (Department of Anatomy and Molecular Cell Biology, Nagoya University Graduate School of Medicine) ,  Fujimoto Toyoshi (Department of Anatomy and Molecular Cell Biology, Nagoya University Graduate School of Medicine)
Material： Acta Histochemica et Cytochemica (Web)  (Acta Histochem Cytochem (Web))
Volume： 50  Issue： 5  Page： 141-147(J-STAGE)  Publication year： 2017 
JST Material Number： U0129A  ISSN： 1347-5800  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *electron microscopy ,...
Semi thesaurus term： *ホスファチジルイノシトール3,4-ビスホスフェート

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Author keywords (5)： phosphatidylinositol 34-bisphosphate ,  electron microscopy ,  freeze-fracture ,  hydrogen peroxide ,  platelet-derived growth factor

JST classification (1)： Microscopic methods of living organisms  (EA03050C)

Reference (31)：

• 1 Alessi, D. R., James, S. R., Downes, C. P., Holmes, A. B., Gaffney, P. R., Reese, C. B. and Cohen, P. (1997) Characteri­zation of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha. Curr. Biol. 7; 261-269.
• 2 Balla, T. (2007) Imaging and manipulating phosphoinositides in living cells. J. Physiol. 582; 927-937.
• 3 Bansal, V. S., Caldwell, K. K. and Majerus, P. W. (1990) The isolation and characterization of inositol polyphosphate 4-phosphatase. J. Biol. Chem. 265; 1806-1811.
• 4 Cheng, J., Fujita, A., Yamamoto, H., Tatematsu, T., Kakuta, S., Obara, K., Ohsumi, Y. and Fujimoto, T. (2014) Yeast and mammalian autophagosomes exhibit distinct phosphatidyl­inositol 3-phosphate asymmetries. Nat. Commun. 5; 3207.
• 5 Chiang, H. C., Wang, L., Xie, Z., Yau, A. and Zhong, Y. (2010) PI3 kinase signaling is involved in Abeta-induced memory loss in Drosophila. Proc. Natl. Acad. Sci. U S A 107; 7060-7065.

Terms in the title (4)： ホスファチジルイノシトール ,  分布 ,  観察 ,  電子顕微鏡法