Art

J-GLOBAL ID：201702290678438560   Reference number：17A1825563

A protective role of IRF3 and IRF7 signalling downstream TLRs in the development of vein graft disease via type I interferons

I型インターフェロンによる静脈移植片疾患の発症におけるIRF3とIRF7シグナル伝達下流TLRの保護的役割【Powered by NICT】

Author (10)： Simons K. H. (Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands) ,  Simons K. H. (Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands) ,  Peters H. A. B. (Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands) ,  Peters H. A. B. (Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands) ,  Jukema J. W. (Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands) ,  Jukema J. W. (Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands) ,  de Vries M. R. (Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands) ,  de Vries M. R. (Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands) ,  Quax P. H. A. (Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands) ,  Quax P. H. A. (Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands)
Material： Journal of Internal Medicine  (J Intern Med)
Volume： 282  Issue： 6  Page： 522-536  Publication year： 2017 
JST Material Number： A0865B  ISSN： 0954-6820  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： BACKGROUND: Toll like receptor...

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Thesaurus term： immunohistochemistry ,  macrophage ,  vessel wall ,  interaction ,  in vitro experiment ,  *Toll like receptor ,  inflammatory cytokine ,  vascular smooth muscle cell ,  interferon beta ,  gene ,  hyperplasia
Semi thesaurus term： Toll様受容体4 ,  Toll様受容体3 ,  *インターフェロン制御因子3 , 【Automatic Indexing@JST】

Author keywords (5)： Interferon regulatory factor ,  toll like receptor ,  type I interferon ,  vascular remodelling ,  vein graft disease

JST classification (3)： Cell physiology in general  (EF02010S) ,  Immunological reaction in general  (ED03010T) ,  Infectious immunity  (ED03030P)

Terms in the title (10)： I型インターフェロン ,  静脈移植 ,  疾患 ,  発症 ,  IRF3 ,  IRF7 ,  シグナル伝達 ,  下流 ,  TLR ,  役割