Art

J-GLOBAL ID：201702291061693978   Reference number：17A0815252

Intratumoral bidirectional transitions between epithelial and mesenchymal cells in triple-negative breast cancer

三重陰性乳癌における上皮および間葉細胞の間での腫瘍内両方向転換

Author (10)： Yamamoto Mizuki (Division of Cellular and Molecular Biology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan) ,  Sakane Kota (Division of Cellular and Molecular Biology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan) ,  Tominaga Kana (Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan) ,  Gotoh Noriko (Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan) ,  Niwa Takayoshi (Department of Breast and Endocrine Surgery, The University of Tokyo Hospital, Tokyo, Japan) ,  Kikuchi Yasuko (Department of Breast and Endocrine Surgery, The University of Tokyo Hospital, Tokyo, Japan) ,  Tada Keiichiro (Department of Breast and Endocrine Surgery, The University of Tokyo Hospital, Tokyo, Japan) ,  Goshima Naoki (Molecular Profiling Research Center for Drug Discovery, National Institute of Advanced Industrial Science and Technology, Tokyo, Japan) ,  Semba Kentaro (Department of Life Science and Medical Bio-Science, Waseda University, Tokyo, Japan) ,  Inoue Jun-ichiro (Division of Cellular and Molecular Biology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan)
Material： Cancer Science (Web)  (Cancer Sci (Web))
Volume： 108  Issue： 6  Page： 1210-1222  Publication year： 2017 
JST Material Number： U0505A  ISSN： 1349-7006  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： mesenchymal cell ,...

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Author keywords (5)： Breast cancer ,  cancer development ,  EMT ,  EMT-inducing transcription factor ,  MET

JST classification (2)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Cell physiology in general  (EF02010S)

Reference (40)：

• Lamouille S, Xu J, Derynck R. Molecular mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell Biol 2014; 15: 178-96.
• De Craene B, Berx G. Regulatory networks defining EMT during cancer initiation and progression. Nat Rev Cancer 2013; 13: 97-110.
• Peinado H, Olmeda D, Cano A. Snail, Zeb and bHLH factors in tumour progression: An alliance against the epithelial phenotype? Nat Rev Cancer 2007; 7: 415-28.
• Miyazono K. Transforming growth factor-beta signaling in epithelial-mesenchymal transition and progression of cancer. Proc Jpn Acad Ser B Phys Biol Sci 2009; 85: 314-23.
• Heerboth S, Housman G, Leary M et al. EMT and tumor metastasis. Clin Transl Med 2015; 4: 6.

Terms in the title (7)： 三重 ,  乳癌 ,  上皮 ,  間葉細胞 ,  腫瘍 ,  両方向 ,  転換