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J-GLOBAL ID：201702295232763985   Reference number：17A0573871

Black soybean seed coat polyphenols prevent AAPH-induced oxidative DNA-damage in HepG2 cells

クロダイズ種皮ポリフェノールはAAPH誘導酸化的DNA損傷をHepG2細胞において予防する

Author (11)： Yoshioka Yasukiyo (Organization of Advanced Science and Technology, Kobe University) ,  Li Xiu (Graduate School of Agricultural Science, Kobe University) ,  Zhang Tianshun (Graduate School of Agricultural Science, Kobe University) ,  Mitani Takakazu (Organization of Advanced Science and Technology, Kobe University) ,  Mitani Takakazu (Graduate School of Agricultural Science, Kobe University) ,  Yasuda Michiko (Organization of Advanced Science and Technology, Kobe University) ,  Nanba Fumio (Research & Development Department, Fujicco Co., Ltd.) ,  Toda Toshiya (Research & Development Department, Fujicco Co., Ltd.) ,  Yamashita Yoko (Graduate School of Agricultural Science, Kobe University) ,  Ashida Hitoshi (Organization of Advanced Science and Technology, Kobe University) ,  Ashida Hitoshi (Graduate School of Agricultural Science, Kobe University)
Material： Journal of Clinical Biochemistry and Nutrition  (JCBN)
Volume： 60  Issue： 2  Page： 108-114(J-STAGE)  Publication year： 2017 
JST Material Number： X0851A  ISSN： 0912-0009  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Glycine max ,...
Semi thesaurus term： LC-MS/MS analysis

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Author keywords (5)： procyanidin ,  8-OHdG ,  ROS ,  LC-MS/MS ,  hepatocytes

JST classification (2)： Vegetables and processed vegetable products  (FJ11020O) ,  Molecular genetics in general  (EC02010J)

Substance index (2)： AAPH ,  8-Hydroxy-2'-deoxyguanosine

Reference (40)：

• 1 Dröge W. Free radical in the physiological control of cell function. Physiol Rev 2002; 82: 47-95.
• 2 Friedman SL. Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J Biol Chem 2000; 275: 2247-2250.
• 3 Svegliati Baroni G, D'Ambrosio L, Ferretti G, et al. Fibrogenic effect of oxidative stress on rat hepatic stellate cells. Hepatology 1998; 27: 720-726.
• 4 Halliwell B. Free radicals and antioxidants: a personal view. Nutr Rev 1994; 52 (8 Pt 1): 253-265.
• 5 Devasagayam TP, Tilak JC, Boloor KK, Sane KS, Ghaskadbi SS, Lele RD. Free radicals and antioxidants in human health: current status and future prospects. J Assoc Physicians India 2004; 52: 794-804.

Terms in the title (8)： ダイズ ,  種皮 ,  ポリフェノール ,  AAPH ,  誘導 ,  酸化的DNA損傷 ,  HepG2細胞 ,  予防