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J-GLOBAL ID：201702295644418640   Reference number：17A1639718

Activated FGFR3 promotes bone formation via accelerating endochondral ossification in mouse model of distraction osteogenesis

活性化されたFGFR3は仮骨延長術のマウスモデルにおける軟骨内骨化を加速を介して骨形成を促進する【Powered by NICT】

Author (12)： Osawa Yusuke (Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, Japan) ,  Osawa Yusuke (Division of Neurogenetics, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Japan) ,  Matsushita Masaki (Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, Japan) ,  Matsushita Masaki (Division of Neurogenetics, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Japan) ,  Hasegawa Sachi (Department of Orthopaedic Surgery, Aichi Prefectural Colony Central Hospital, Japan) ,  Esaki Ryusaku (Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, Japan) ,  Esaki Ryusaku (Division of Neurogenetics, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Japan) ,  Fujio Masahito (Department of Oral and Maxillofacial Surgery, Nagoya University Graduate School of Medicine, Japan) ,  Ohkawara Bisei (Division of Neurogenetics, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Japan) ,  Ishiguro Naoki (Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, Japan) ,  Ohno Kinji (Division of Neurogenetics, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Japan) ,  Kitoh Hiroshi (Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, Japan)
Material： Bone (New York)  (Bone (N.Y.))
Volume： 105  Page： 42-49  Publication year： 2017 
JST Material Number： E0177D  ISSN： 8756-3282  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Achondroplasia (ACH) is one of...

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Thesaurus term： fibroblast ,  osteoblast ,  short stature ,  Bone Density ,  *osteogenesis ,  protocol ,  morphology ,  gene ,  transgenic mouse ,  wild-type mouse ,  Collagen Type X ,  Bone Regeneration ,  *Intracartilaginous ossification ,  *mouse model ,  *FGF receptor 3

Author keywords (5)： Achondroplasia ,  Fibroblast growth factor receptors 3 ,  Mice ,  Distraction osteogenesis ,  Bone regeneration

JST classification (4)： Basic medicine on musculoskeletal system  (GG01020B) ,  Function of cell components  (EF03060C) ,  Skeletal system  (EJ10030R) ,  Diagnostics of congenital diseases, deformities.  (GD03020G)

Terms in the title (8)： 活性化 ,  FGFR3 ,  仮骨延長術 ,  マウスモデル ,  軟骨内骨化 ,  加速 ,  骨形成 ,  促進