Art

J-GLOBAL ID：201702298812113371   Reference number：17A1047506

New Modalities for Challenging Targets in Drug Discovery

薬物発見における挑戦的なターゲットのための新しい方法【Powered by NICT】

Author (13)： Valeur Eric (Cardiovascular and Metabolic Diseases, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Pepparedsleden 1, Molndal, 431 83, Sweden) ,  Gueret Stephanie M. (Cardiovascular and Metabolic Diseases, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Pepparedsleden 1, Molndal, 431 83, Sweden) ,  Gueret Stephanie M. (AstraZeneca MPI Satellite Unit, Abteilung Chemische Biologie, Max Planck Institut fuer Molekulare Physiologie, Dortmund, Germany) ,  Adihou Helene (Cardiovascular and Metabolic Diseases, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Pepparedsleden 1, Molndal, 431 83, Sweden) ,  Adihou Helene (AstraZeneca MPI Satellite Unit, Abteilung Chemische Biologie, Max Planck Institut fuer Molekulare Physiologie, Dortmund, Germany) ,  Gopalakrishnan Ranganath (Cardiovascular and Metabolic Diseases, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Pepparedsleden 1, Molndal, 431 83, Sweden) ,  Gopalakrishnan Ranganath (AstraZeneca MPI Satellite Unit, Abteilung Chemische Biologie, Max Planck Institut fuer Molekulare Physiologie, Dortmund, Germany) ,  Lemurell Malin (Cardiovascular and Metabolic Diseases, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Pepparedsleden 1, Molndal, 431 83, Sweden) ,  Waldmann Herbert (Abteilung Chemische Biologie, Max Planck Institut fuer Molekulare Physiologie, Dortmund, Germany) ,  Waldmann Herbert (Fakultaet fuer Chemie und Chemische Biologie, Technische Universitaet Dortmund, Germany) ,  Grossmann Tom N. (Chemical Genomics Centre of the Max Planck Society, Dortmund, Germany) ,  Grossmann Tom N. (Department of Chemistry & Pharmaceutical Sciences, VU University Amsterdam, The Netherlands) ,  Plowright Alleyn T. (Cardiovascular and Metabolic Diseases, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Pepparedsleden 1, Molndal, 431 83, Sweden)
Material： Angewandte Chemie. International Edition  (Angewandte Chemie. International Edition in English)
Volume： 56  Issue： 35  Page： 10294-10323  Publication year： 2017 
JST Material Number： H0127B  ISSN： 1433-7851  CODEN： ACIEAY  Document type： Article
Article type： 文献レビュー  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Our ever-increasing understand...

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Thesaurus term： *intermolecular interaction ,  *product development ,  new drug ,  cell physiology ,  peptide ,  oligonucleotide ,  small molecule
Semi thesaurus term： *protein-protein interaction ,  *protein nucleic acid interaction ,  *drug development

Author keywords (4)： drug conjugates ,  macrocycles ,  oligonucleotides ,  peptides

JST classification (1)： Physicochemical pharmacy in general  (GV01010J)

Terms in the title (3)： 薬物 ,  発見 ,  ターゲット