Research theme for competitive and other funds (3)：
2025 - 2028 「新種・新属の真菌」の「未利用生合成遺伝子」を活用した新規化合物の探索
2021 - 2024 真菌に寄生する『菌寄生菌』を探索源とした抗真菌薬リード化合物の探索
2019 - 2020 III型分泌機構阻害剤aurodoxの標的タンパク質の同定 および機能解析
Papers (44)：
Emi Arakawa, Yoshihiro Watanabe, Hayama Tsutsumi, Akari Ikeda, Tomoyasu Hirose, Noriko Sato, Takumi Chinen, Akira Také, Hiroki Kanto, Yuki Inahashi, et al. Ufisonitriles A and B, Antimalarial Isonitriles with Mitochondrial Function Inhibitory Activity Produced by Amycolatopsis sp. OK19-0009. Journal of natural products. 2025
Sho Kato, Yoshihiro Watanabe, Hiroki Kojima, Yuta Kikuchi, Mika Watabe, Yuki Hayashi, Ryoya Ibuki, Hayama Tsutsumi, Yuki Inahashi, Kenichi Nonaka, et al. Hygromycin B Is a Highly Versatile Inducer of Secondary Metabolite Production Applicable Across Diverse Fungal Taxa. Journal of natural products. 2025
Karin Hamada, Yoshihiro Watanabe, Yuta Kikuchi, Hayama Tsutsumi, Haruki Azami, Hiroki Kojima, Sho Kato, Akihiro Sugawara, Yuki Inahashi, Kenichi Nonaka, et al. New benzoyl sesquiterpenoid, aoganolide, produced by Talaromyces sp. KTF-0021 strain (laeA-introduced mutant of FKI-5759 strain). The Journal of Antibiotics. 2025
Yuta Kikuchi, Hayama Tsutsumi, Yoshihiro Watanabe, Hiroki Nakahara, Sho Ito, Yoshihiko Noguchi, Yuta Awano, Masanobu Kasuga, Masato Iwatsuki, Tomoyasu Hirose, et al. Harnessing the Biosynthetic Diversity of Actinomycetes: Discovery of Unique Natural Products Through Comparative Genomic and Metabolic Analysis. Chemistry (Weinheim an der Bergstrasse, Germany). 2025. e01912
Kazuki Tani, Miyu Wakatsuki, Masahiro Wada, Kenichi Nonaka, Yuta Kikuchi, So-ichiro Kimura, Yoshihiro Watanabe, Rei Hokari, Tomoyasu Hirose, Masako Honsho, et al. Discovery of Structurally Diverse γ-Pyrone-Type Diterpenoids Produced by the Fungus Mariannaea sp. FKR-1011 from Zamami Island. Journal of Natural Products. 2025
岡野太一, 木村奏一朗, 中原大生, 吉岡修志, 渡邊善洋, 渡邊善洋, 千成恒, 千成恒, 橋本瑞希, 小島裕貴, et al. Search and optimization of antimalarial seeds derived from fungi. 日本薬学会年会要旨集(Web). 2025. 145th
鈴木澪央那, 堤隼馬, 堤隼馬, 石井皓大, 小牧彩乃, 山川結加, 渡邊善洋, 渡邊善洋, 鈴木智博, 岩月正人, et al. Uncovering the formation mechanism of a polycyclic structure with an unusual alkenyl ether moiety in the biosynthesis of macrodiolide antibiotic. 日本薬学会年会要旨集(Web). 2025. 145th
