Kinoshita Akira

キノシタアキラ | Kinoshita Akira

Affiliation and department：

Research field (1)： Medical biochemistry

Research keywords (8)： Camurati-Engelmann Disease , TGF-beta 1 , bone , Gillespie syndrome , ITPR1 , proteasome , ear wax , interferon regulatory factor 6

Research theme for competitive and other funds (10)：

2023 - 2026 骨系統疾患治療のゲームチェンジャー:ヒストン修飾を標的にした治療法の開発
2019 - 2022 網羅的発現解析が明らかにした眼特異的転写産物は角膜再生の新規キープレーヤーか?
2015 - 2018 患者由来iPS細胞を用いたTGFシグナル異常骨系統疾患の治療法の開発
2012 - 2015 プロテアソーム不全と炎症疾患:細胞ストレスによる新たな発症機序の解明
2013 - 2014 カムラチー・エンゲルマン病の治療法の確立: 新規遺伝子探索、モデル構築、分子標的治療薬の探索

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Papers (101)：

Daisuke Hatta, Kaito Kanamoto, Shiho Makiya, Kaori Watanabe, Tatsuya Kishino, Akira Kinoshita, Koh-Ichiro Yoshiura, Naohiro Kurotaki, Keiro Shirotani, Nobuhisa Iwata. Proline-rich transmembrane protein 2 knock-in mice present dopamine-dependent motor deficits. Journal of biochemistry. 2023
八田大典, 金本海斗, 眞喜屋志穂, 渕上由貴, 川上茂, 木下晃, 吉浦孝一郎, 黒滝直弘, 城谷圭朗, 岩田修永. 発作性誘発性ジスキネジアの原因分子PRRT2の線条体ドーパミン伝達と運動制御における役割. 日本神経精神薬理学会年会プログラム・抄録集. 2023. 53回. 157-157
Hideki Kosako, Yusuke Yamashita, Ken Tanaka, Hiroyuki Mishima, Ryuta Iwamoto, Akira Kinoshita, Shin-ichi Murata, Koichi Ohshima, Koh-ichiro Yoshiura, Takashi Sonoki, et al. Intestinal Mucosa-Associated Lymphoid Tissue Lymphoma Transforming into Diffuse Large B-Cell Lymphoma in a Young Adult Patient with Neurofibromatosis Type 1: A Case Report. Medicina. 2022. 58. 12. 1830
Miki Torigoe, Yoko Obata, Hiro Inoue, Kenta Torigoe, Akira Kinoshita, Takehiko Koji, Hiroshi Mukae, Tomoya Nishino. Hydroxychloroquine suppresses anti-GBM nephritis via inhibition of JNK/p38 MAPK signaling. Clinical and experimental nephrology. 2022. 27. 2. 110-121
Yo Hamaguchi, Hiroyuki Mishima, Tomoko Kawai, Shinji Saitoh, Kenichiro Hata, Akira Kinoshita, Koh-Ichiro Yoshiura. Identification of unique DNA methylation sites in Kabuki syndrome using whole genome bisulfite sequencing and targeted hybridization capture followed by enzymatic methylation sequencing. Journal of human genetics. 2022. 67. 12. 711-720

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MISC (60)：

北之園英明, 安東恒史, 今泉芳孝, 小林裕児, 三嶋博之, 木下晃, 田口正剛, 坂本光, 加藤丈晴, 佐藤信也, et al. Combination therapy of PRMT5 inhibitor and PHD2 inhibitor (IOX4) for adult T-cell leukemia/lymphoma. 日本血液学会学術集会抄録(Web). 2021. 83rd
小林裕児, 安東恒史, 今泉芳孝, 北之園英明, 三嶋博之, 木下晃, 田口正剛, 坂本光, 加藤丈晴, 佐藤信也, et al. RUNX1 as a therapeutic target for adult T-cell leukemia/lymphoma. 日本血液学会学術集会抄録(Web). 2021. 83rd
鳥越未来, 小畑陽子, 井上大, 鳥越健太, 木下晃, 小路武彦, 西野友哉. ヒドロキシクロロキンは抗GBM抗体腎炎の進展を抑制する. 日本腎臓学会誌. 2020. 62. 4. 310-310
Miki Torigoe, Yoko Obata, Hiro Inoue, Kenta Torigoe, Akira Kinoshita, Takehiko Koji, Tomoya Nishino. HYDROXYCHLOROQUINE PREVENTS ANTI-GBM GLOMERULONEPHRITIS IN RATS. NEPHROLOGY DIALYSIS TRANSPLANTATION. 2020. 35. 663-663
森田修平, 竹島健, 古川安志, 浦木進丞, 稲葉秀文, 有安宏之, 岩倉浩, 古田浩人, 西理宏, 三嶋博之, et al. 褐色細胞腫を合併したWaardenburg症候群の1例. 日本内分泌学会雑誌. 2019. 95. Suppl.Update. 149-150

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Education (1)：

1999 - 2002 Nagasaki University Graduate School of Biomedical Sciences

Work history (6)：

2022/01 - 現在 Nagasaki University Atomic Bomb Disease Institute
2012 - 2021 Nagasaki University
2011 - 2012/03 Nagasaki University Graduate School of Biomedical Sciences
2007 - 2011 Nagasaki University Graduate School of Biomedical Sciences
2005 - 2007 University of Iowa Department of Pediatrics Postdoctoral fellow

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Committee career (1)：

2016 - 現在日本人類遺伝学会評議委員

Awards (1)：

2001/10 - 日本人類遺伝学会奨励賞

Association Membership(s) (3)：

The American Society of Human Genetics , The Japanese Society for Gene Diagnosis and Therapy , THE JAPAN SOCIETY OF HUMAN GENETICS

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