Rchr
J-GLOBAL ID：201801000288571757   Update date: Oct. 26, 2025

TAKUJIRO HOMMA

ホンマ タクジロウ | TAKUJIRO HOMMA
Affiliation and department：
Osaka Metropolitan University Graduate School of Medicine Department of Basic Medical Science

About Osaka Metropolitan University Graduate School of Medicine Department of Basic Medical Science


Job title： Lecturer
Research field  (3)： Pathobiochemistry ,  Molecular biology ,  Medical biochemistry
Research keywords  (3)： 酸化ストレス ,  分子生物学 ,  生化学
Research theme for competitive and other funds  (4)：
  • 2022 - 2025 細胞内のレドックスバランスを制御するChaCファミリーの病態生理機能の解明
  • 2021 - 2024 Elucidation of cell cycle dependence of ferrotosis and active oxygen production pathway caused by cell proliferation
  • 2016 - 2018 Studies on the physiological role of ascorbic acid in SOD1/Akr1a double knockout mice with increased oxidative stress
  • 2015 - 2018 Roles of transsulfuration-mediated cysteine uptake and hydrogen sulfide in liver
Papers (73)：
  • Tsukasa Osaki, Takujiro Homma, Yuya Soma, Satoshi Miyata, Yumi Matsuda, Junichi Fujii. Ascorbic acid deficiency promotes metabolic remodeling and pulmonary fibrosis that leads to respiratory failure in Sod1 and Akr1a double-knockout mice. Redox biology. 2025. 85. 103749-103749
  • Takujiro Homma, Takehiro Nakagaki, Takuya Nishinakagawa, Yurie Morita, Ryuichiro Atarashi, Shigeru Kakuta, Yoichiro Iwakura, Noriyuki Nishida, Daisuke Ishibashi. Oligoadenylate synthetase 1a suppresses prion infection through binding to cellular prion protein. Brain. 2025
  • Takujiro Homma, Chihiro Tada, Moeka Yamauchi, Yuto Matsumoto, Shinji Matsunaga, Shuji Akai, Hiroaki Gotoh, Shuhei Tomita. Identification of a novel tetrahydroxynaphthalene derivative by chemical screening with ferroptosis inhibitory activity and promising therapeutic potential. Free radical research. 2025. 1-11
  • Takuya Nishinakagawa, Takujiro Homma, Aoi Ikeda, Mai Hazekawa, Yurie Morita, Takehiro Nakagaki, Ryuichiro Atarashi, Noriyuki Nishida, Daisuke Ishibashi. Lysine residues are not required for proteasome-mediated proteolysis of cellular prion protein. Biochemical and biophysical research communications. 2024. 735. 150807-150807
  • Yuki Nishino, Takujiro Homma, Kan-Ichiro Ihara, Junichi Fujii, Taro Tachibana, Chikako Yokoyama. Generation of Rat Monoclonal Antibody for Human Nucleolin. Monoclonal antibodies in immunodiagnosis and immunotherapy. 2023. 42. 4. 145-149
ｍore...
Books (5)：
  • Glutathione: Biosynthesis, Functions and Biological Implications (Pal Perjesi, ed).
    Nova Science Publishers 2019 ISBN:9781536147414
  • Ferroptosis in Health and Disease (Daolin Tang, ed).
    Springer Nature 2019 ISBN:9783030267803
  • Oxidative stress and dysfunction of the intracellular proteolytic machinery: a pathological hallmark of nonalcoholic fatty liver disease.
    Elsevier 2019 ISBN:9780128144664
  • Ascorbic Acid: Properties, Synthesis and Applications.
    Nova Science Publishers 2017 ISBN:9781634859004
  • Superoxide Dismutase (SOD): Sources, Therapeutic Uses and Health Benefits.
    Nova Science Publishers 2016 ISBN:9781634854603
Lectures and oral presentations  (47)：
  • ジペプチダーゼCNDP2は腎がんにおいてフェロトーシス感受性を調節する
    (第153回日本薬理学会関東部会 2025)
  • FDA 承認薬を基盤としたCuproptosis 抑制化合物の探索と評価
    (第75回日本薬学会関西支部総会・大会 2025)
  • ジペプチダーゼ CNDP2 を介した腎フェロトーシス感受性の制御機構
    (第33回日本Cell Death学会学術集会 2025)
  • 酸化ストレス誘導型マウスモデルにおけるビタミンCの生体保護機能
    (日本ビタミン学会第77回大会 2025)
  • HIF-ChaC1軸の関与する腎障害制御メカニズムの解明
    (第50回日本微小循環学会総会 第78回日本酸化ストレス学会学術集会 2025)
ｍore...
Education (3)：
  • 2009 - 2014 Nagasaki University Graduate School of Biomedical Sciences
  • 2007 - 2009 Tokyo University of Science
  • 2003 - 2007 Tokyo University of Science
Professional career (3)：
  • 博士(医学) (長崎大学)
  • 修士(薬学) (東京理科大学)
  • 学士(薬学) (東京理科大学)
Work history (2)：
  • 2022/04 - 現在 大阪公立大学 大学院医学研究科 分子病態薬理学 講師
  • 2014/06 - 2022/03 山形大学大学院医学系研究科 生化学分子生物学講座 助教
Awards (6)：
  • 2024/06 - 日本薬理学会関東部会 Young Investigator Award
  • 2024/04 - Cells 2023 Outstanding Reviewer Award
  • 2022/05 - 第75回日本酸化ストレス学会学術集会・最優秀ポスター賞
  • 2022/03 - 第40回Cytoprotection研究会・奨励賞
  • 2021/05 - 日本酸化ストレス学会・学術奨励賞
Show all
Association Membership(s) (4)：
The Japanese Pharmacological Society ,  SOCIETY FOR FREE RADICAL RESEARCH JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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