Inoue Minoru

Affiliation and department：

Research field (2)： Radiology , Tumor biology

Research keywords (10)： microendoscopy , edge computing , Intravital imaging , Reactive Oxygen Species , Serum albumin , Radiation Therapy , Neutrophil Extracellular Traps , Redox Homeostasis , Cancer , Radiation Biology

Research theme for competitive and other funds (7)：

2021 - 2024 放射線照射により生じる血管内酸化ストレス及びがん転移形質の誘導機構の解明
2022 - 2023 腫瘍内モザイク強度放射線治療の実現を見据えた腫瘍内顕微観察法の開発
2020 - 2021 プレシジョン放射線治療の実現を見据えた機械学習によるがん放射線感受性予測法の開発
2019 - 2021 血清アルブミンの酸化度に基づくがんの放射線感受性予測法の開発
2019 - 2020 がんゲノム医療への導入を見据えたアルブミンのオミックス解析の意義の検討

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Papers (23)：

Noriko Kishi, Masahiro Yoneyama, Hiroyuki Inoo, Minoru Inoue, Hiraku Iramina, Akiyoshi Nakakura, Tomohiro Ono, Hideaki Hirashima, Takanori Adachi, Norimasa Matsushita, et al. Protocol of a phase II study to evaluate the efficacy and safety of deep-inspiration breath-hold daily online adaptive radiotherapy for centrally located lung tumours (PUDDING study). Radiation oncology (London, England). 2024. 19. 1. 32-32
Hajime Torizuka, Minoru Inoue, Yusuke Iizuka, Yosuke Yamada, Takashi Mizowaki. Anaplastic Transformation of Follicular Thyroid Carcinoma in Pulmonary Metastasis With Gradually Progressive Intra-tumoral Cavitation: A Case Report. Cureus. 2022
Minoru Inoue, Masahiro Enomoto, Michio Yoshimura, Takashi Mizowaki. Pharmacological inhibition of sodium-calcium exchange activates NADPH oxidase and induces infection-independent NETotic cell death. Redox Biology. 2021. 43. 101983-101983
井上実, 吉村通央, Bratman Scott V., Liu Fei-Fei, 溝脇尚志. 肺癌・転移性腫瘍に対する新しい診断・治療法抗NETs療法による転移性肺腫瘍の予防戦略. 日本癌治療学会学術集会抄録集. 2020. 58回. WS16-3
Yusuke Iizuka, Tomohiro Katagiri, Kengo Ogura, Minoru Inoue, Kiyonao Nakamura, Takashi Mizowaki. Comparison of thyroid hormone withdrawal and recombinant human thyroid-stimulating hormone administration for adjuvant therapy in patients with intermediate- to high-risk differentiated thyroid cancer. Annals of Nuclear Medicine. 2020. 34. 10. 736-741

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MISC (3)：

井上実, 吉村通央, BRATMAN Scott V., LIU Fei-Fei, 溝脇尚志. 抗NETs療法による転移性肺腫瘍の予防戦略. 日本癌治療学会学術集会(Web). 2020. 58th
井上実, 吉村通央, 溝脇尚志, Liu Fei-Fei, Bratman Scott V. アルブミン酸化により生じる酸化還元バランス不均衡は肺優位なNETosisと転移を促進する(Plasma Redox Imbalance Caused by Albumin Oxidation Promotes Lung-Predominant NETosis and Metastasis). 日本癌学会総会記事. 2019. 78回. E-1076
小林稔, 曽麗華, 後藤容子, 井上実, 板坂聡, 吉村通央, 原田浩, 平岡真寛. IDH3はHIF-1alphaを安定化して腫瘍増殖を亢進する. 2013

Lectures and oral presentations (7)：

Inhibition of the forward-mode sodium-calcium exchange induces infection-independent NETotic cell death via activation of NADPH oxidase
(2021 SfRBM & MCW Redox Biology Symposium 2021)
Plasma Redox Imbalance Caused by Albumin Oxidation Promotes Lung-Predominant NETosis and Metastasis in Patients Treated With Definitive Radiation Therapy
(2018 ASTRO annual meeting 2018)
Intravascular redox balance regulates NETosis and cancer metastasis
(Multidisciplinary Head and Neck Cancers Symposium 2018)
Starvation condition triggers neutrophil extracellular traps
(Personalizing Cancer Medicine in 2016 Conference 2016)
PLK1 blockade enhances therapeutic effects of radiation by inducing cell cycle arrest at the mitotic phase
(2014)

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Education (2)：

2011 - 2015 京都大学大学院医学研究科博士課程
2000 - 2006 Hamamatsu University School of Medicine Faculty of Medicine School of Medicine

Professional career (1)：

博士(医学) (京都大学)

Work history (3)：

2018/04 - 現在 Kyoto University Hospital Department of Radiation Oncology Assistant Professor
2015/04 - 2018/03 University of Toronto, Princess Margaret Cancer Centre Postdoctoral Fellow
2009/04 - 2011/03 静岡県立静岡がんセンター放射線治療科非常勤医師

Awards (2)：

2021/10 - Society for Leukocyte Biology Abstract Award Inhibition of Na+/Ca2+ exchanger activates NADPH oxidase and induces NETosis
2018/10 - American Society for Radiation Oncology Abstract Award(Basic/Translational Science Award) Plasma Redox Imbalance Caused by Albumin Oxidation Promotes Lung-Predominant NETosis and Metastasis in Patients Treated With Definitive Radiation Therapy

Association Membership(s) (6)：

Society for Leukocyte Biology , Society for Redox Biology and Medicine , JAPAN SOCIETY OF CLINICAL ONCOLOGY , THE JAPANESE CANCER ASSOCIATION , JAPAN RADIOLOGICAL SOCIETY , JAPANESE SOCIETY FOR RADIATION ONCOLOGY

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