Sugiko Watanabe

ワタナベスギコ | Sugiko Watanabe

Affiliation and department：

Research field (3)： Pathobiochemistry , Tumor biology , General surgery, pediatric surgery

Research keywords (5)：がん , ゲノム安定性 , DNA damage response , chromatin regulation , 遺伝性腫瘍

Research theme for competitive and other funds (6)：

2023 - 2026 Analysis of cell-free DNA targeted sequence to develop of novel strategies for endocrine therapy-resistant breast cancer
2020 - 2023 細胞老化に伴う細胞質クロマチン断片蓄積の分子機構と発がんとの関係解明
2014 - 2017 Molecular research of non-histone lysine methylation in cancer epigenome and its potential as a therapeutic target
2009 - 2009 膵臓癌の癌幹細胞的特性に対する構造的クロマチン因子の役割解明と治療的アプローチ
2007 - 2008 The role of high mobility group A proteins in cancers

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Papers (27)：

Naohiro Kuwayama, Tomoya Kujirai, Yusuke Kishi, Rina Hirano, Kenta Echigoya, Lingyan Fang, Sugiko Watanabe, Mitsuyoshi Nakao, Yutaka Suzuki, Kei-ichiro Ishiguro, et al. HMGA2 directly mediates chromatin condensation in association with neuronal fate regulation. Nature Communications. 2023. 14. 1
Sugiko Watanabe, Makoto Iimori, David Virya Chan, Eiji Hara, Hiroyuki Kitao, Yoshihiko Maehara. MDC1 methylation mediated by lysine methyltransferases EHMT1 and EHMT2 regulates active ATM accumulation flanking DNA damage sites. Scientific Reports. 2018. 8. 1. 10888
Akiko Takahashi, Tze Mun Loo, Ryo Okada, Fumitaka Kamachi, Yoshihiro Watanabe, Masahiro Wakita, Sugiko Watanabe, Shimpei Kawamoto, Kenichi Miyata, Glen N Barber, et al. Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells. Nature communications. 2018. 9. 1. 1249-1249
Atsushi Okuma, Aki Hanyu, Sugiko Watanabe, Eiji Hara. p16(Ink4a) and p21(Cip1/Waf1) promote tumour growth by enhancing myeloid-derived suppressor cells chemotaxis. NATURE COMMUNICATIONS. 2017. 8. 1. 2050
Masaki Takasugi, Ryo Okada, Akiko Takahashi, David Virya Chen, Sugiko Watanabe, Eiji Hara. Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2. NATURE COMMUNICATIONS. 2017. 8. 15729

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MISC (52)：

渡邉すぎ子, 有馬信之, 谷川富夫, 稲吉厚, 村本一浩, 西村令喜. 非浸潤性乳管癌を疑い切除生検により確定診断し得た症例の検討. 日本乳癌検診学会学術総会プログラム抄録集. 2023. 33回. 251-251
谷川富夫, 村本一浩, 西村令喜, 稲吉厚, 渡邉すぎ子, 菊竹高志. CDK4/6阻害剤本邦認可を契機に、延命、QOLの保持に極めて有益であったDe novo StageIV乳癌の治療経験. 日本乳癌学会総会プログラム抄録集. 2023. 31回. 472-472
谷川富夫, 村本一浩, 稲吉厚, 菊竹高志, 渡邉すぎ子. 転移再発乳癌に対するOlaparibの使用経験. 日本乳癌学会総会プログラム抄録集. 2022. 30回. EP11-80
渡邉すぎ子, 佐々木瑠美, 柊中智恵子, 後藤理沙, 山本豊, 大場隆. 術前遺伝学的検査の現状と展望-複数の乳がん関連遺伝子変異を疑った症例から学ぶ-. 日本遺伝性腫瘍学会学術集会プログラム・抄録集. 2022. 28th
谷川富夫, 村本一浩, 稲吉厚, 渡邉すぎ子, 有馬信之. 最近経験した乳腺基質産生癌の2例. 日本乳癌学会総会プログラム抄録集. 2021. 29回. 222-222

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Books (2)：

Education (2)：

Professional career (1)：

Work history (7)：

2021/07 - 現在 Kumamoto University Institute of Molecular Embryology and Genetics
2020/08 - 2021/06 Kumamoto University Institute of Molecular Embryology and Genetics
2015/08 - 2020/08 Osaka University Research Institute for Microbial Diseases
2013/04 - 2015/08 Kyushu University
2009/06 - 2013/03 Danish Cancer Society Research Center Post-doctoral fellow・senior scientist

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Committee career (1)：

Association Membership(s) (6)：

日本遺伝性腫瘍学会 , 日本人類遺伝学会 , 日本乳癌学会 , THE JAPANESE CANCER ASSOCIATION , THE JAPANESE SOCIETY OF GASTROENTEROLOGICAL SURGERY , JAPAN SURGICAL SOCIETY

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