Rchr
J-GLOBAL ID:201801001067965951
Update date: Sep. 29, 2024
Ujihara Yoshihiro
ウジハラ ヨシヒロ | Ujihara Yoshihiro
Affiliation and department:
Job title:
Associate Professor
Research field (1):
Biomedical engineering
Research theme for competitive and other funds (31):
- 2022 - 2027 血管組織内微視的力学場の定量による瘤発生機構解明と力学環境操作による病理応答制御
- 2023 - 2026 Resilience Biology -What are the molecular mechanisms that support the resilience of life?-
- 2021 - 2026 材料的・流体的力学的挙動による大動脈解離発症メカニズムの解明と医療応用への試み
- 2021 - 2025 哺乳類心筋細胞のT管膜構造の維持機構の解明と進化的意義の探求
- 2021 - 2024 光学-分子動力学計算融合による細胞膜損傷の分子レベルでの理解と定量化技術の開発
- 2020 - 2024 Creation of innovative myocardial regeneration strategy with soft and highly dividing cardiomyocytes
- 2020 - 2024 脳梗塞後リハビリテーションによる大脳基底核経路ネットワーク改変メカニズムの解明
- 2022 - 2024 冬眠中の心筋細胞のT管膜維持機構の解明による革新的心不予防法の創出
- 2020 - 2023 運動と循環の起源と進化:新たな指標による地球環境変遷との関連解明
- 2020 - 2023 心筋細胞の張力伝達ネットワークによる機械受容機構解明と心不全治療への展開
- 2020 - 2022 Interpretation of regulatory system of fetal cardiovascular development with re-evaluation of substance transport characteristics in fetal circulation
- 2019 - 2022 哺乳類と異なる戦略で優れた心機能を発揮する鳥類に学ぶ革新的心不全治療の創出
- 2018 - 2021 A novel approach to myocardial regeneration based on hypoxia-dependent, multi-hierarchical intrauterine environment.
- 2017 - 2021 Investigation of regulatory mechanism of cardiac mechanics by molecular-spring connectin and clinical application for heart failure
- 2017 - 2021 心筋細胞のT管支持機構と崩壊機序の解明による新規心不全治療戦略の創出
- 2018 - 2020 Identification of mechanical signal from intercalated discs
- 2017 - 2020 Preliminary study for cardiac regeneration using novel cell cycle promoter Fam64a
- 2017 - 2020 Mechanotransduction on cardiac physiology
- 2016 - 2019 Elucidation of the mechanosensing function in heart by a muscle elastic protein connectin
- 2014 - 2017 Information control for a linkage between macro cardiac function and gene expression: physiomic analysis of responses to oxygen environment
- 2014 - 2017 Elucidation of molecular mechanism of mechanotransduction in the heart
- 2014 - 2017 心筋細胞のT管膜維持機構の解明:T管膜局所Ca2+管理機構の分子基盤と生理的意義
- 2014 - 2016 The maintenance of cardiac structure and function by mechanical feedback system involving multiple organ systems.
- 2014 - 2016 Quantification of hemolytic conditions using pico-photo sensing of chemoluminescence caused by hemoglobin leakage
- 2013 - 2016 The role of mechanosensor molecule TRPV2 during monocyte transmigration across vascular endothelium in atherogenesis.
- 2013 - 2015 Physiomic analysis of the regulatory mechanism of cardiomyocyte
- 2012 - 2015 Development of a Miniature Laser-Induced Underwater Shockwave-Generating Device using an Optical Fiber
- 2011 - 2014 Physiomic analyses of cardiac hypertrophy and ventricular geometry of in cardiac regulation
- 2011 - 2013 心臓の機械的負荷への適応機構解明:カルシウム動態と冠微小循環リモデリング
- 2011 - 2012 Development of visualization of soft tissue morphology and protein concentration by X-ray phase-contrast computed tomography.
- 2009 - 2011 内部構造を考慮した細胞力学モデルの構築と細胞骨格のリモデリングの解明
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Papers (43):
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Muhammad Harith Bin Zamri, Yoshihiro Ujihara, Masanori Nakamura, Mohammad, R.K. Mofrad, Shukei Sugita. Decoding the effect of hydrostatic pressure on TRPV1 lower gate conformation by molecular dynamics simulation. International Journal of Molecular Sciences. 2022. 23. 13. 7366
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Ken Hashimoto, Aya Kodama, Momoko Ohira, Misaki Kimoto, Reiko Nakagawa, Yuu Usui, Yoshihiro Ujihara, Akira Hanashima, Satoshi Mohri. Postnatal expression of cell cycle promoter Fam64a causes heart dysfunction by inhibiting cardiomyocyte differentiation through repression of Klf15. iScience. 2022. 25. 5. 104337-104337
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Wataru Fukui, Yoshihiro Ujihara, Masanori Nakamura, Shukei Sugita. Direct visualization of interstitial flow distribution in aortic walls. Scientific Reports. 2022. 12. 5381
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Yuhei Ogura, Hioroaki Ito, Shukei Sugita, Masanori Nakamura, Yoshihiro Ujihara. Decrease in Ca2+ Concentration in Quail Cardiomyocytes Is Faster than That in Rat Cardiomyocytes. Processes. 2022. 10. 3. 508
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Differences in Pressure Resistance and Tissue Structure of Ventricles between Aquatic, Semiaquatic, and Terrestrial Anura. 2021. 59. 6. 162-168
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MISC (19):
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Oxygen environment and cardiac regeneration. 2022. 48. 10. 30-33
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Yuki Katanosaka, Makoto Shibuya, Yoshihiro Ujihara, Satoshi Mohri, Keiji Naruse. TRPV2 is Crucial for the Development of Intercalated Discs in Mouse Hearts. BIOPHYSICAL JOURNAL. 2019. 116. 3. 538A-538A
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Yuki Katanosaka, Yoshihiro Ujihara, Yumiko Chiba, Satoshi Mohri, Keiji Naruse. TRPV2 is Crucial for the Development of Excitation-Contraction Coupling in Neonatal Cardiomyocytes. BIOPHYSICAL JOURNAL. 2018. 114. 3. 484A-484A
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Yoshihiro Ujihara, Satomi Takatsu, Keiji Naruse, Satoshi Mohri, Yuki Katanosaka. The Role of NCX1 on the Maintenance of T-Tubule Architecture in Pressure-Overloaded Hearts. BIOPHYSICAL JOURNAL. 2018. 114. 3. 619A-619A
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UJIHARA Yoshihiro, HASHIMOTO Ken, MOHRI Satoshi, KATANOSAKA Yuki. 1D42 Mechanical signaling via TRPV2 in cardiomyocytes. 2016. 2016. 28. "1D42-1"-"1D42-4"
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Books (2):
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A mechanical cell model and its application to cellular biomechanics
In Tech 2011
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Effects of cytoskeletal structures on elastic and viscoelastic properties of cells in soft tissues
World Scientific Publishers 2007
Lectures and oral presentations (179):
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Effect of hydrostatic pressure on TRV1 conformation using molecular dynamics simulation
(15th World Congress on Computational Mechanics (WCCM-XV) 8th Asian Pacific Congress on Computational Mechanics (APCOM-VIII) 2022)
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Analysis of Ca concentration changes evoked by electrical stimulation in cardiomyocytes isolated from quails
(The 9th World Congress of Biomechanics 2022)
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Quantification of pressure tolerance of Anura ventricles in different habitats
(The 9th World Congress of Biomechanics 2022)
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Changes in ventricular structure and passive stiffness during vertebrate terrestrialization: Comparison of ventricles of extant Anura from different habitats
(the 9th World Congress of Biomechanics 2022)
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メカニカルストレスによる心臓突然死と心不全発症を防ぐ新規蛋白質
(第64回日本生体医工学会大会 2022)
more...
Education (3):
- 2008 - 2011 Osaka University Graduate School, Division of Engineering Science
- 2006 - 2008 Osaka University Graduate School, Division of Engineering Science
- 2002 - 2006 Osaka University Faculty of Engineering Science
Professional career (3):
- 学士(工学) (大阪大学)
- 修士(工学) (大阪大学)
- 博士(工学) (大阪大学)
Work history (3):
- 2018/10/01 - 現在 Nagoya Institute of Technology Graduate School of Engineering Omohi College Associate Professor
- 2018/04/01 - 2018/09/30 Kawasaki Medical School
- 2011/04/01 - 2018/03/31 Kawasaki Medical School
Committee career (4):
- 2021 - 現在 日本機械学会 バイオエンジニアリング部門 広報委員
- 2019/05 - 現在 日本機械学会 バイオエンジニアリング部門 生体機能の解明とその応用に関する研究会 幹事
- 2021/10 - 2022/01 日本機械学会 第32回バイオフロンティア講演会 幹事
- 2017/10 - 2021/03 日本機械学会 バイオエンジニアリング部門 若手による次世代戦略委員会 幹事
Awards (13):
- 2021/12 - JSME Bioengineering Division Outstanding Abstract Runners-up Award at the AP Biomech 2021
- 2021/12 - JSME Bioengineering Division Outstanding Abstract Award at the AP Biomech 2021
- 2021/12 - JSME Bioengineering Division Outstanding Abstract Award at the AP Biomech 2021
- 2021/09/17 - 日本生体医工学会 生体医工学シンポジウム2021 ベストリサーチアワード
- 2021/04 - 文部科学省 令和3年度科学技術分野の文部科学大臣表彰 若手科学者学者賞
- 2020/03 - 日本機械学会東海支部 2019年度日本機械学会東海支部賞研究賞
- 2017/12/15 - 日本機械学会バイオエンジニアリング部門 瀬口賞
- 2017 - 両備檉園記念財団 生物学研究 奨励賞
- 2016/04/21 - 日本機械学会 日本機械学会奨励賞(研究)
- 2015/05/08 - 日本生体医工学会 研究奨励賞・阪本研究刊行助成賞・阿部賞
- 2010/09 - 日本生体医工学会 生体医工学会シンポジウム ベストリサーチアワード
- 2009/12 - 3rd East Asian Pacific tudent Workshop on Nano-Biomedical Engineering Best Active Contribution Award
- 2009/12 - 3rd East Asian Pacific tudent Workshop on Nano-Biomedical Engineering Poster Presentation Award
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Association Membership(s) (5):
日本進化学会
, 生物物理学会(Biophysical Society)
, 日本生理学会
, 日本生体医工学会
, 日本機械学会
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