Research field (3):
Nutrition and health science
, Rehabilitation science
, Molecular biology
Research keywords (9):
健康寿命
, Vitamin D
, DNAメチル化
, CYP
, Gene expression
, Mineral metabolism in bone
, Rickets
, Chronic Kidney Disease
, Phosphorus
Research theme for competitive and other funds (10):
2021 - 2024 生体内リン代謝と老化を繋ぐ分子機序解明の研究基盤
2021 - 2024 抗老化因子を制御するミネラル栄養学の確立
2021 - 2024 小腸FGF19産生・分泌を基盤とした健康長寿を目指す栄養療法
2023 - 2024 穀類ポリフェノールによる「腸老化」予防効果
2023 - 2024 小腸老化モデルマウスの確立と次世代健康長寿戦略
2020 - 2021 香辛料成分による骨量および骨格筋機能強化作用の解明
2018 - 2021 腎・骨格筋dual維持機構を介した慢性腎臓病の栄養療法
2017 - 2020 New strategy for overcoming Pi toxicity by modulating the function of inorganic phosphate (Pi) network.
2015 - 2018 リン・ビタミンD代謝を制御する多臓器連関の解明
2015 - 2016 穀類ポリフェノールによる慢性腎臓病重症化予防効果
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Papers (56):
Minori Uga, Ichiro Kaneko, Yuji Shiozaki, Megumi Koike, Naoko Tsugawa, Peter W Jurutka, Ken-Ichi Miyamoto, Hiroko Segawa. The Role of Intestinal Cytochrome P450s in Vitamin D Metabolism. Biomolecules. 2024. 14. 6
Yoji Kato, Asahi Sakanishi, Kaoru Matsuda, Mai Hattori, Ichiro Kaneko, Miyu Nishikawa, Shinichi Ikushiro. Covalent adduction of serotonin-derived quinones to the SARS-CoV-2 main protease expressed in a cultured cell. Free radical biology & medicine. 2023. 206. 74-82
Sumire Sasaki, Yuji Shiozaki, Ai Hanazaki, Megumi Koike, Kazuya Tanifuji, Minori Uga, Kota Kawahara, Ichiro Kaneko, Yasuharu Kawamoto, Pattama Wiriyasermkul, et al. Tmem174, a regulator of phosphate transporter prevents hyperphosphatemia. Scientific Reports. 2022. 12. 1. 6353-6353
Sumire Sasaki, Megumi Koike, Kazuya Tanifuji, Minori Uga, Kota Kawahara, Aoi Komiya, Mizuki Miura, Yamato Harada, Yuki Hamaguchi, Shohei Sasaki, et al. Dietary polyphosphate has a greater effect on renal damage and FGF23 secretion than dietary monophosphate. The journal of medical investigation : JMI. 2022. 69. 3.4. 173-179
Aleksandra Grozić, Keaton Coker, Christopher M Dussik, Marya S Sabir, Zhela Sabir, Arianna Bradley, Lin Zhang, Jin Park, Steven Yale, Ichiro Kaneko, et al. Identification of putative transcriptomic biomarkers in irritable bowel syndrome (IBS): Differential gene expression and regulation of TPH1 and SERT by vitamin D. PloS one. 2022. 17. 10. e0275683
Endocrine loop of Vitamin D homeostasis in liver, kidney or intestine.
(The 78th Annual Meeting of Japan Society of Nutrition and Food Science, JSNFS, KFN and SCJ Joint Symposium on Trends in Food Science, Function and Processing 2024)
The Endocrine Society
, THE JAPANESE SOCIETY OF NUTRITION AND DIETETICS
, THE VITAMIN SOCIETY OF JAPAN
, JAPAN SOCIETY OF NUTRITION AND FOOD SCIENCE
, Japanese Society for Food Factors