Park Eun Jeong

Affiliation and department：
Job title： Associate Professor

Research field (2)： Pathobiochemistry , Immunology

Research keywords (10)： MicroRNA , Cell-adhesion molecules , Innate lymphoid cell , Sepsis , Exosomes , Extracellular vesicles , Cell migration , Inflammatory bowel diseases , Intestinal epithelial cell , Intestinal immunity

Research theme for competitive and other funds (15)：

2022 - 2025 Targeting integrin signaling for the treatment of COVID-19
2022 - 2025 Elucidation of role of thrombomodulin in recovery of mucosal tissue in inflammatory bowel disease
2022 - 2025 Identifying PD-L1-mediated immune dysregulation in post-cardiac arrest syndrome.
2022 - 2025 Exosomes and miRNAs of intestinal epithelial cells regulate inflammations in sepsis
2021 - 2024 Elucidation of the mechanism by which exosomal PD-L1 induces septic immune paralysis

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Papers (65)：

Ryo Esumi, Asami Ito-Masui, Eiji Kawamoto, Mami Ito, Tomoyo Hayashi, Toru Shinkai, Atsuya Hane, Fumito Okuno, Eun Jeong Park, Ryuji Kaku, et al. Correlation Between Social Network Structure and Well-being of Healthcare Workers in Intensive Care Units: A Prospective Observational Study. Interactive Journal of Medical Research. 2023
Takanori Yamaguchi, Arong Gaowa, Eun Jeong Park, Isao Tawara, Motomu Shimaoka. Recombinant soluble thrombomodulin attenuates cisplatin-induced intestinal injury by inhibiting intestinal epithelial cell-derived cytokine secretion. Molecular Biology Reports. 2023. 50. 10. 8459-8467
Eun Jeong Park, Hariom Yadav, Tej Pratap Singh. Editorial: Microbiota in skin inflammatory diseases. Frontiers in immunology. 2023. 14. 1235314
Eun Jeong Park, Motomu Shimaoka. Integrin-Mediated Exosomal Homing to Organs. Methods in molecular biology (Clifton, N.J.). 2023. 2668. 145-158
Siqingaowa Caidengbate, Yuichi Akama, Anik Banerjee, Khwanchanok Mokmued, Eiji Kawamoto, Arong Gaowa, Louise D. McCullough, Motomu Shimaoka, Juneyoung Lee, Eun Jeong Park. MicroRNA Profiles in Intestinal Epithelial Cells in a Mouse Model of Sepsis. Cells. 2023. 12. 5. 726

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MISC (56)：

朴恩正, 島岡要. 腸管上皮細胞のマイクロRNA分析から,敗血症に特徴的な臓器特異的炎症反応制御の複雑さが見える. 細胞. 2023. 55. 11. 898-901
朴恩正, Caidengbate Siqingaowa, 赤間悠一, Banerjee Anik, Mokmued Khwanchanok, 川本英嗣, 阿栄高娃, Lee Juneyoung, McCullough Louise D., 島岡要. 敗血症モデルマウスの腸管上皮細胞のマイクロRNAプロファイル. Shock: 日本Shock学会雑誌. 2023. 37. 1. 83-83
Gaowa Arong, Park Eun Jeong, Shimaoka Motomu. Mucosal and Skin Surface Barrier(Irisin promotes intestinal epithelial cell proliferation via Wnt/beta-catenin and integrin beta 1/FAK signaling pathway). 日本免疫学会総会・学術集会記録(0919-1984)51巻Proceedings. 2022. 51. WS19-09-P
Park Eun Jeong, Obeng Gideon, Appiah Michael G., Kawamoto Eiji, Gaowa Arong, Shimaoka Motomu. miR-200c-3pによるインテグリンを介した細胞接着と焦点接着斑形成の制御(Integrin-mediated cell adhesion and focal adhesion formation are regulated by miR-200c-3p). 日本血栓止血学会誌. 2022. 33. 2. 244-244
赤間悠一, 朴恩正, 佐藤尚子, 川本英嗣, 高娃阿栄, 伊藤温志, 江角亮, 池尻薫, 今井寛, 島岡要. 敗血症マウスモデルでのICU関連筋力低下に対するProgrammed cell Death protein-1(PD-1)阻害の効果. Shock: 日本Shock学会雑誌. 2022. 36. 1. 37-37

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Patents (5)：

Detoxified mutants of Escherichia coli heat-labile enterotoxin
Nucleic acid encoding angiogenesis inhibitor
A novel angiogenesis inhibitor
Novel angiogenesis inhibitor
Angiogenesis inhibitor

Books (3)：

Mucosal Vaccines (Ed. Hiroshi Kiyono): Innovation for Preventing Infectious Diseases. 2nd Edition
Elsevier 2020
Examination of immunological memory induced by MucoRice-CTB, a rice-based oral vaccine.
The Tojuro Iijima Foundation for Food Science and Technology (Annual Report) 2014
Leukocyte Adhesion (Ed. Klaus Ley). Current Topics in Membranes, Volume 64
Elsevier 2009

Lectures and oral presentations (60)：

miRNA-200c-3p controls alpha4beta7 integrin-mediated T-cell adhesion and migration
(52nd Annual Meeting of Japanese Society for Immunology 2024)
Recombinant soluble thrombomodulin attenuates cisplatin-induced intestinal injury by inhibiting intestinal epithelial cell-derived cytokine secretion
(52nd Annual Meeting of Japanese Society for Immunology 2024)
MicroRNA Profiles in Intestinal Epithelial Cells in a Mouse Model of Sepsis
(37th Annual Meeting of Japan Shock Society 2023)
Irisin promotes intestinal epithelial cell proliferation via Wnt/beta-catenin and integrin beta 1/FAK signaling pathway
(51st Annual Meeting of Japanese Society for Immunology 2022)
Integrin-mediated cell adhesion and focal adhesion formation are regulated by miR-200c-3p
(The 44th Congress of the Japanese Society on Thrombosis and Hemostasis 2022)

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Education (3)：

2000 - 2004 Osaka University Graduate School of Medicine Course of Molecular Medicine
1993 - 1995 Sungkyunkwan University College of Science Biological Sciences
1986 - 1993 Sungkyunkwan University College of Science Biological Sciences

Professional career (1)：

医学博士 (大阪大学)

Work history (6)：

2014/10 - 現在 Mie University Graduate School of Medicine Associate Professor
2023/11 - 2023/11 Thammasat University Faculty of Medicine Visiting Professor
2012 - 2014 The University of Tokyo The Institute of Medical Science Project Assistant Professor
2009 - 2011 Harvard Medical School Instructor
2004 - 2009 Harvard Medical School Postdoctoral researcher

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Committee career (1)：

2009 - 2010 Immune Disease Institute Institutional Animal Care and Use Committee Member

Awards (5)：

2019/01 - Mie University Medical School/Graduate School of Medicine Education Contribution Award
2016/04 - Mie Prefecture Healthcare Management Center Research Scientific Award Mechanism of mucosal immune system down-regulation induced by colon cancer
2013/04 - Japan Society of Nutrition and Food Science Scientific Research Award Examination of immunological memory induced by MucoRice-CTB, a rice-based oral vaccine
2009 - GlaxoSmithKline-Immune Disease Institute Alliance Research Fellowship Award
2003 - Yoneyama Rotary Foundation Scholarship

Association Membership(s) (3)：

THE JAPANESE SOCIETY FOR IMMUNOLOGY , THE JAPANESE SOCIETY ON THROMBOSIS AND HEMOSTASIS , The Japan Shock Society

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