Hattori Yoshihide

ハットリヨシヒデ | Hattori Yoshihide

Homepage URL (1)： http://www.bnct.osakafu-u.ac.jp

Research field (1)： Pharmaceuticals - chemistry and drug development

Research theme for competitive and other funds (8)：

2024 - 2027 Development of a Novel Treatment Method Using Boron Radioisotope Compounds Targeting Brain and Spinal Cord Tumors
2022 - 2025 Developing of radiolabeling method and Investigation of in vivo pharmacokinetics of BSH using in BNCT
2020 - 2023 Establishment of multi-target neutron capture therapy with multiple boron drugs for brain tumor
2020 - 2023 Development of Hydrophilic Boron Cluster Containing Molecular-Targeted Drugs
2019 - 2022 Clinical application of boron-conjugated adenovirus vector for neutron capture therapy

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Papers (28)：

Yoshihide Hattori, Tooru Andoh, Shinji Kawabata, Naonori Hu, Hiroyuki Michiue, Hiroyuki Nakamura, Takahiro Nomoto, Minoru Suzuki, Takushi Takata, Hiroki Tanaka, et al. Proposal of recommended experimental protocols for in vitro and in vivo evaluation methods of boron agents for neutron capture therapy. Journal of radiation research. 2023
Hideki Kashiwagi, Yoshihide Hattori, Shinji Kawabata, Ryo Kayama, Kohei Yoshimura, Yusuke Fukuo, Takuya Kanemitsu, Hiroyuki Shiba, Ryo Hiramatsu, Toshihiro Takami, et al. Multi-Targeted Neutron Capture Therapy Combined with an 18 kDa Translocator Protein-Targeted Boron Compound Is an Effective Strategy in a Rat Brain Tumor Model. Cancers. 2023. 15. 4
Tsubasa Watanabe, Yu Sanada, Yoshihide Hattori, Minoru Suzuki. Correlation between the expression of LAT1 in cancer cells and the potential efficacy of boron neutron capture therapy. Journal of radiation research. 2022. 64. 1. 91-98
Shiori Hirase, Ayako Aoki, Yoshihide Hattori, Kenta Morimoto, Kosuke Noguchi, Ikuo Fujii, Tomoka Takatani-Nakase, Shiroh Futaki, Mitsunori Kirihata, Ikuhiko Nakase. Dodecaborate-Encapsulated Extracellular Vesicles with Modification of Cell-Penetrating Peptides for Enhancing Macropinocytotic Cellular Uptake and Biological Activity in Boron Neutron Capture Therapy. Molecular pharmaceutics. 2022. 19. 4. 1135-1145
Yoshihide Hattori, Miki Ishimura, Youichirou Ohta, Hiroshi Takenaka, Shinji Kawabata, Mitsunori Kirihata. Dodecaborate Conjugates Targeting Tumor Cell Overexpressing Translocator Protein for Boron Neutron Capture Therapy. ACS medicinal chemistry letters. 2022. 13. 1. 50-54

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MISC (89)：

中瀬生彦, 服部能英, 切畑光統. 機能性ペプチドを用いたBNCTホウ素化合物の細胞内導入技術. 生体膜と薬物の相互作用シンポジウム講演要旨集. 2023. 44th
服部能英, 石村美紀, 石村美紀, 大田洋一郎, 大田洋一郎, 竹中宏誌, 竹中宏誌, 中瀬生彦, 切畑光統. Synthesis of Bifuctional Dodecaborate for the development of Theranostic Type Boron Carrier. 日本薬学会年会要旨集(Web). 2023. 143rd
服部能英, 切畑光統. Dynamics of BPA, a tumor targeted boron amino acid for boron neutron capture therapy (BNCT). Dojin News. 2022. 182
金井泰和, 渡辺利光, 大田洋一郎, 井口佳哉, 堺俊博, 仲定宏, 服部能英, 上原幸樹, 片岡昌治, 金井好克, et al. [18F]FBPA新規合成法における加水分解条件の検討. 核医学. 2021. 58. Suppl. S232-S232
平瀬詩織, 青木絢子, 野口公輔, 森本健太, 服部能英, 切畑光統, 中瀬生彦. ホウ素中性子捕捉療法におけるエクソソームを用いたホウ素薬剤の細胞内導入. 日本DDS学会学術集会プログラム予稿集. 2021. 37th. 136-136

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Patents (6)：

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Professional career (1)：

博士(理学) (近畿大学)

Work history (4)：

2024/04 - 現在 Osaka Metropolitan University
2023/10 - 2024/03 有限会社IPE 研究員
2023/06 - 2024/03 Tohoku University
2022/04 - 2023/09 Osaka Metroplitan University Research Center of Boron Neutron Capture Therapy Research +ecturer

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