Rchr
J-GLOBAL ID:201801001298986617   Update date: Oct. 20, 2021

Junko Oshima

オオシマ ジュンコ | Junko Oshima
Affiliation and department:
Job title: Research Professor Emeritus
Other affiliations (1):
Homepage URL  (2): http://www.pathology.washington.edu/faculty/oshimahttp://www.pathology.washington.edu/research/werner/registry/registry.html
Research field  (1): Internal medicine - General
Research keywords  (5): Progeria ,  Internal medicine ,  Aging ,  Genome ,  Genetics
Research theme for competitive and other funds  (6):
  • 2019 - 2025 Genetic and Non-Genetic Modulators of Morbidity/Disability Compression in aLarge Population-Based Study of Cognitive and Physical Impairment with Emphasis on Alzheimer's Disease and Related Dementias
  • 2016 - 2022 International Registry of Werner Syndrome
  • 2017 - 2020 早老症の遺伝原因同定と、正常加齢への寄与の検索
  • 2016 - 2018 Genetic Modulations of Morbidity Compression:A Population-Based Study
  • 2012 - 2018 International Registry of Werner Syndrome
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Papers (129):
  • Renuka Kandhaya-Pillai, Deyin Hou, Jiaming Zhang, Xiaomeng Yang, Goli Compoginis, Takayasu Mori, Tamara Tchkonia, George M Martin, Fuki M Hisama, James L Kirkland, et al. SMAD4 mutations and cross-talk between TGF-β/IFNγ signaling accelerate rates of DNA damage and cellular senescence, resulting in a segmental progeroid syndrome-the Myhre syndrome. GeroScience. 2021. 43. 3. 1481-1496
  • Junko Oshima, George M Martin, Fuki M Hisama. Werner Syndrome. 2021
  • George M Martin, Fuki M Hisama, Junko Oshima. Review of How Genetic Research on Segmental Progeroid Syndromes Has Documented Genomic Instability as a Hallmark of Aging But Let Us Now Pursue Antigeroid Syndromes!. The journals of gerontology. Series A, Biological sciences and medical sciences. 2021. 76. 2. 253-259
  • Iram Hussain, Ruilin Raelene Jin, Howard B A Baum, Jerry R Greenfield, Sophie Devery, Chao Xing, Robert A Hegele, Barbara G Carranza-Leon, Macrae F Linton, Frank Vuitch, et al. Multisystem Progeroid Syndrome With Lipodystrophy, Cardiomyopathy, and Nephropathy Due to an LMNA p.R349W Variant. Journal of the Endocrine Society. 2020. 4. 10. bvaa104
  • Renuka Kandhaya-Pillai, Fuki M. Hisama, Stephanie A. Bucks, Soe Yarzar, Haroula Korovou, George M. Martin, Junko Oshima. Novel LMNA mutations in Greek and Myanmar Patients with Progeroid Features and Cardiac Manifestations. Aging Pathobiology and Therapeutics. 2020. 2. 2. 101-105
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MISC (7):
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Lectures and oral presentations  (18):
  • The Spectrum of WRN Mutations in Werner Syndrome Patients
    (日本老年医学会 2021)
  • Genetics of Aging: Molecular Mechanisms of Progeroid Syndromes”
    (Seminars in Medical Sciences Series 2019)
  • Genetics of Aging: Molecular Mechanisms of Progeroid Syndromes
    (Leading Seminar, Chiba University 2019)
  • International Registry of Werner Syndrome: Search for progeroid syndrome mutations and mechanisms
    (Cold Spring Harbor Laboratory Meeting “Mechanism of Aging”. 2018)
  • International Registry of Werner Syndrome: Search for progeroid syndrome mutations and mechanisms
    (International Meeting on RECQ Helicases and Related Diseases 2018, 2018)
more...
Education (3):
  • 1986 - 1992 Boston University School of Medicine Department of Biochemistry
  • 1978 - 1984 University of Tsukuba School
  • 1975 - 1978 Nagano Prefectural Nagano Senior Hihg School
Professional career (2):
  • MD, PhD, FACMG
  • M. D. (筑波大学医学専門学群)
Work history (13):
  • 2016/08/01 - University of Washington School of Medicine Pathology Research Professor Emeritus
  • 2015/12/01 - Chiba University Graduate School of Medicine Innovation Medicine Professor
  • 2013/07/01 - 2015/07/31 University of Washington School of Medicine Pathology Research Professor
  • 2001/06/01 - 2013/06/30 University of Washington School of Medicine Pathology Research Associate Professor
  • 1996/03/01 - 2001/05/31 University of Washington School of Medicine Pathology Research Assistant Professor
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Committee career (19):
  • 2006/01 - 現在 American Federation for Aging Research, New York, NY National Scientific Advisory
  • 2021/04 - NIH study section, NIH NIA ZAG1 LRP
  • 2020/04 - NIH study section, NIH NIA ZAG1 LRP
  • 2019/05 - NIH study section NIH NIA ZAG1 ZIJ-4 (M5) LRP
  • 2018/10 - NIH study section NIH NIA ZAG1 ZIJ-G (J4) PPG
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Awards (1):
  • 1999 - Gerontological Society of America Nathan Shock New Investigators Award
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