Rchr
J-GLOBAL ID:201801001495698470   Update date: Aug. 24, 2024

Kuwahara Yasumichi

クワハラ ヤスミチ | Kuwahara Yasumichi
Affiliation and department:
Job title: Professor
Research field  (3): Fetal medicine/Pediatrics ,  Medical biochemistry ,  Genomics
Research keywords  (9): Rhabdoid tumor ,  Chromatin Remodeling ,  SWI/SNF complex ,  SNF5 ,  RUNX1 ,  小児悪性固形腫瘍 ,  Developmental Disorder ,  行動分析学 ,  行動医学
Research theme for competitive and other funds  (13):
  • 2022 - 2025 Establishment of new intervention methods for hematopoietic transcriptional control for clinical application.
  • 2022 - 2025 Functional analysis of transcription factors and novel SWI/SNF complexes in the tumorigenesis of rhabdoid tumors.
  • 2019 - 2022 造血転写制御への新規介入方法の探索とその臨床応用に向けた研究
  • 2019 - 2022 スーパーエンハンサー機能異常を介した悪性ラブドイド腫瘍の分子病態の解明
  • 2019 - 2022 造血転写制御への新規介入方法の探索とその臨床応用に向けた研究
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Papers (39):
  • Hajime Hosoi, Mitsuru Miyachi, Satoshi Teramukai, Satomi Sakabayashi, Kunihiko Tsuchiya, Yasumichi Kuwahara, Rie Onodera, Kotone Matsuyama, Isao Yokota, Hiroshi Hojo, et al. Results of the JRS-I LRA0401 and LRB0402 Japan Rhabdomyosarcoma Study Group trials for low-risk embryonal rhabdomyosarcoma. International journal of clinical oncology. 2024
  • Yaniv Kazansky, Daniel Cameron, Helen S Mueller, Phillip Demarest, Nadia Zaffaroni, Noemi Arrighetti, Valentina Zuco, Yasumichi Kuwahara, Romel Somwar, Marc Ladanyi, et al. Overcoming clinical resistance to EZH2 inhibition using rational epigenetic combination therapy. Cancer discovery. 2024
  • Yasumichi Kuwahara, Tomoko Iehara, Akifumi Matsumoto, Tsukasa Okuda. Recent insights into the SWI/SNF complex and the molecular mechanism of hSNF5 deficiency in rhabdoid tumors. Cancer medicine. 2023
  • Masamitsu Mikami, Tatsuya Masuda, Takuya Kanatani, Mina Noura, Katsutsugu Umeda, Hidefumi Hiramatsu, Hirohito Kubota, Tomoo Daifu, Atsushi Iwai, Etsuko Yamamoto Hattori, et al. RUNX1-Survivin Axis Is a Novel Therapeutic Target for Malignant Rhabdoid Tumors. Molecules and cells. 2022. 45. 12. 886-895
  • Haruka Shinohara, Rie Sawado, Makoto Nakagawa, Ayuna Hattori, Kazutsune Yamagata, Kimiharu Tauchi, Jumpei Ito, Yasumichi Kuwahara, Tsukasa Okuda, Chitose Ogawa, et al. Dual targeting of EZH1 and EZH2 for the treatment of malignant rhabdoid tumors. Molecular therapy oncolytics. 2022. 27. 14-25
more...
MISC (21):
Education (2):
  • 2000 - 2004 Kyoto Prefectural University of Medicine Graduate School of Medical Science
  • 1990 - 1996 Kyoto Prefectural University of Medicine
Professional career (1):
  • 博士(医学) (京都府立医科大学)
Work history (12):
  • 2024/08 - 現在 Kyoto Prefectural University of Medicine Department of Kyoto Pediatric Community-Based Medicine Professor
  • 2022/07 - 2024/07 Kyoto Prefectural University of Medicine Department of Biochemistry and Molecular Biology Associate professor
  • 2015/08 - 2022/06 Kyoto Prefectural University of Medicine
  • 2013/04 - 2015/07 Kyoto Prefectural University of Medicine
  • 2011/04 - 2013/03 Kyoto Prefectural University of Medicine
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Committee career (2):
  • 『小児がん 診療ガイドライン』2016 年版 作成委員
  • 小児血液がん学会 評議員
Awards (2):
  • 2024/03 - 日本子ども健康科学会 学術大会優秀発表賞
  • 2005 - 京都府立医科大学学友会 第15回 京都府立医科大学学友会 青蓮賞
Association Membership(s) (17):
日本医学教育学会 ,  日本心理学会 ,  日本場面緘黙研究会 ,  日本行動医学会 ,  強度行動障害医療学会 ,  日本子ども健康科学会 ,  THE JAPANESE ASSOCIATION FOR BEHAVIOR ANALYSIS ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  JAPANESE SOCIETY OF PEDIATRIC PSYCHIATRY AND NEUROLOGY ,  THE JAPANESE SOCIETY OF HEMATOLOGY ,  日本エピジェネティクス研究会 ,  AMERICAN ASSOCIATION FOR CANCER RESEARCH ,  JAPAN SOCIETY OF CLINICAL ONCOLOGY ,  THE JAPANESE CANCER ASSOCIATION ,  THE JAPANESE SOCIETY OF PEDIATRIC HEMATOLOGY/ONCOLOGY ,  JAPAN PEDIATRIC SOCIETY
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