Rchr
J-GLOBAL ID：201801001703797819   Update date: Nov. 18, 2024

Ohashi Nami

Ohashi Nami
Affiliation and department：
Showa Pharmaceutical University

About Showa Pharmaceutical University


Research field  (1)： Pharmaceuticals - chemistry and drug development
Research theme for competitive and other funds  (2)：
  • 2015 - 2018 Development of mid-size drugs based on peptidomimetic
  • 2010 - 2011 蛍光を用いたPKCリガンドの2段階結合評価系の構築とバイオセンサーへの応用
Papers (55)：
  • Takahiro Ishii, Takuya Kobayakawa, Kouki Matsuda, Kiyomi Nigorikawa, Peter Bolah, Airi Noborio, Kohei Tsuji, Nami Ohashi, Kazuhisa Yoshimura, Wataru Nomura, et al. Discovery of Potent DAG-Lactone Derivatives as HIV Latency Reversing Agents. ACS infectious diseases. 2024
  • Tetsuya Yano, Takahiro Yamada, Hiroaki Isida, Nami Ohashi, Toshimasa Itoh. 2-cyanopyridine derivatives enable N-terminal cysteine bioconjugation and peptide bond cleavage of glutathione under aqueous and mild conditions. RSC Advances. 2024
  • Takahiro Ishii, Takuya Kobayakawa, Kouki Matsuda, Kohei Tsuji, Nami Ohashi, Shingo Nakahata, Airi Noborio, Kazuhisa Yoshimura, Hiroaki Mitsuya, Kenji Maeda, et al. Synthesis and evaluation of DAG-lactone derivatives with HIV-1 latency reversing activity. European journal of medicinal chemistry. 2023. 256. 115449-115449
  • Kohei Tsuji, Takuya Kobayakawa, Kiju Konno, Ami Masuda, Kohei Takahashi, Nami Ohashi, Kazuhisa Yoshimura, Takeo Kuwata, Shuzo Matsushita, Shigeyoshi Harada, et al. Exploratory studies on soluble small molecule CD4 mimics as HIV entry inhibitors. Bioorganic & medicinal chemistry. 2022. 56. 116616-116616
  • Kohei Tsuji, Takahiro Ishii, Takuya Kobayakawa, Nami Ohashi, Wataru Nomura, Hirokazu Tamamura. Fluorescence resonance energy transfer-based screening for protein kinase C ligands using 6-methoxynaphthalene-labeled 1,2-diacylglycerol-lactones. Organic & biomolecular chemistry. 2021. 19. 38. 8264-8271
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MISC (86)：
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Education (3)：
  • 2008 - 2011 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences
  • 2006 - 2008 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences
  • 2002 - 2006 神奈川大学 理学部 生物科学科
Work history (8)：
  • 2019/03 - 現在 昭和薬科大学 医薬分子化学研究室 助教
  • 2017/04 - 2019/03 昭和薬科大学 医薬分子化学研究室 特任助教
  • 2015/04 - 2017/03 東京医科歯科大学 生体材料工学研究所 生体機能分子研究部門 メディシナルケミストリー 特任助教
  • 2013/04 - 2015/03 東京医科歯科大学 生体材料工学研究所 生体機能分子研究部門 メディシナルケミストリー 研究機関研究員
  • 2012/10 - 2013/03 Tokyo Medical and Dental University Institute of Biomaterials and Bioengineering Division of Biomolecular Chemistry
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