Rchr
J-GLOBAL ID:201801002037126056   Update date: Jan. 30, 2024

Imataka Hiroaki

イマタカ ヒロアキ | Imataka Hiroaki
Affiliation and department:
Homepage URL  (1): http://www.eng.u-hyogo.ac.jp/group/group37/
Research field  (1): Systems genomics
Research keywords  (5): artificial cells ,  reconstitution ,  translation ,  protein synthesis ,  synthetic biology
Research theme for competitive and other funds  (19):
  • 2021 - 2027 Comprehensive study of in vivo protein folding in proteostasis network
  • 2022 - 2026 Development of the reconstituted folding/translation-coupled system to analyze relevant diseases
  • 2021 - 2026 Analysis of non-domain type RNA sequences in the mRNA untranslated region
  • 2022 - 2025 ポリアミンが誘導するリピート病の発症機構とその制御による病態抑制効果の解明
  • 2020 - 2024 Molecular mechanism of RAN translation
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Papers (86):
  • Yosuke Ito, Yuhei Chadani, Tatsuya Niwa, Ayako Yamakawa, Kodai Machida, Hiroaki Imataka, Hideki Taguchi. Nascent peptide-induced translation discontinuation in eukaryotes impacts biased amino acid usage in proteomes. Nature communications. 2022. 13. 1. 7451-7451
  • Kodai Machida, Shoma Miyawaki, Kuru Kanzawa, Taiki Hakushi, Tomonori Nakai, Hiroaki Imataka. An in Vitro Reconstitution System Defines the Defective Step in the Biogenesis of Mutated β-Actin Proteins. ACS synthetic biology. 2021. 10. 11. 3158-3166
  • Chihiro Hirayama, Kodai Machida, Kentaro Noi, Tadayoshi Murakawa, Masaki Okumura, Teru Ogura, Hiroaki Imataka, Kenji Inaba. Distinct roles and actions of protein disulfide isomerase family enzymes in catalysis of nascent-chain disulfide bond formation. iScience. 2021. 24. 4. 102296-102296
  • Risa Nobuta, Kodai Machida, Misaki Sato, Satoshi Hashimoto, Yasuhito Toriumi, Shizuka Nakajima, Daiki Suto, Hiroaki Imataka, Toshifumi Inada. eIF4G-driven translation initiation of downstream ORFs in mammalian cells. Nucleic acids research. 2020. 48. 18. 10441-10455
  • Akihiro Oguro, Tomoaki Shigeta, Kodai Machida, Tomoaki Suzuki, Takeo Iwamoto, Senya Matsufuji, Hiroaki Imataka. Translation efficiency affects the sequence-independent +1 ribosomal frameshifting by polyamines. The Journal of Biochemistry. 2020. 168. 2. 139-149
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MISC (7):
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Lectures and oral presentations  (6):
  • ポリアミンがCAG リピート由来の非標準翻訳に与える影響
    (第17 回 無細胞生命科学研究会プログラム 2022)
  • In vitro analysis of noncanonical Translation
    (TOKYO RNA CLUB 30th 2022)
  • In vitro reconstitution and elucidation of noncanonical translation
    (2022)
  • Development of an in vitro translation system reconstituted with human factors and its application
    (2021)
  • 新型コロナウイルス特異的翻訳阻害剤の開発に向けて
    (第15回無細胞科学研究会 2021)
more...
Professional career (1):
  • 農学博士 (東京大学)
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