Nakahata Yasukazu

Affiliation and department：
Job title： associate professor

Research field (1)： Physiology

Research keywords (4)： aging , cellular senescence , NAD+ metabolism , circadian clock

Research theme for competitive and other funds (12)：

2022 - 2025 NAD+による概日リズム回復と老化抑制の関連性解明
2018 - 2021 The mechanism of organ-size determination via social behavior of their progenitor cells in animal development
2017 - 2021 Effects of circadian clock and NAD+ metabolism on cellular scenesence
2016 - 2019 Analysis of transcriptional kinetics of synexpression genes in a single cell
2014 - 2017 The system for fine tuning of signal transduction that maintains the robustness in morphogenesis

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Papers (38)：

Rassul Kuatov, Jiro Takano, Hideyuki Arie, Masaru Kominami, Norifumi Tateishi, Ken-ichi Wakabayashi, Daisuke Takemoto, Takayuki Izumo, Yoshihiro Nakao, Wataru Nakamura, et al. Urolithin A Modulates PER2 Degradation via SIRT1 and Enhances the Amplitude of Circadian Clocks in Human Senescent Cells. Nutrients. 2024. 17. 1. 20-20
Harunori Oda, Eiko Omichi, Eri Oda, Ryosuke Shinohara, Hiroko Oda, Shinya Aoyama, Wataru Tarumi, Xia Ling, Kazuyuki Shinohara, Yasukazu Nakahata. Comparative analysis of chronological and biological aging on the potential of in vitro cultured human adipose-derived mesenchymal stem cells. Acta Medica Nagasakiensia. 2024. 67. 2. 49-60
Yasukazu Nakahata. Impact of Cellular Senescence on Cellular Clocks. Healthy Ageing and Longevity. 2023. 105-125
Liguo Huang, Lit-Chein Chin, Koichi Kimura, Yasukazu Nakahata. Human Placental Extract Delays In Vitro Cellular Senescence through the Activation of NRF2-Mediated Antioxidant Pathway. Antioxidants (Basel, Switzerland). 2022. 11. 8
Phooi-Yee Chang, Lit-Chein Chin, Koichi Kimura, Yasukazu Nakahata. Human placental extract activates a wide array of gene expressions related to skin functions. Scientific reports. 2022. 12. 1. 11031-11031

ｍore...

MISC (5)：

Books (1)：

Sleep and Clocks in Aging and Longevity
Springer International Publishing 2023 ISBN:9783031224676

Education (3)：

Professional career (1)：

Work history (5)：

2019/04 - 現在 Nagasaki Univeristy Associate professor
2009/06 - 2019/03 Nara Institute of Science and Technology Assistant professor
2006/05 - 2009/05 University of California, Irvine Postdoctoral Fellow
2005/09 - 2006/04 Institute of Genetics and Molecular and Cellular Biology Postdoctoral Fellow
2002/04 - 2005/08 Osaka Bioscience Institute Postdoctoral Fellow

Committee career (3)：

Awards (2)：

Association Membership(s) (5)：

日本生化学会 , 日本生理学会 , 日本エピジェネティクス研究会 , 日本分子生物学会 , 日本時間生物学会

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