Ikeda Yoshiki

イケダヨシキ | Ikeda Yoshiki

Affiliation and department：
Job title： Assistant Professor

Research field (1)： Pharmaceuticals - chemistry and drug development

Research theme for competitive and other funds (17)：

2023 - 2027 Development of innovative antibody technology for therapeutics of glioblastoma
2024 - 2026 不妊症治療を目指した細胞接着活性化剤の開発
2022 - 2026 中枢神経系の可塑的変化を病態基盤とする慢性疼痛とうつ病の新規分子機序の解明
2021 - 2026 Development of next-generation-antibodies based on shark VNAR platform
2023 - 2025 マラリア原虫類のオルガネラ恒常性に果たすオートファジー関連因子ATG8の機能解析

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Papers (24)：

Tatsuhiko Ozawa, Yoshiki Ikeda, Liuan Chen, Rigel Suzuki, Atsushi Hoshino, Akira Noguchi, Shunsuke Kita, Yuki Anraku, Emiko Igarashi, Yumiko Saga, et al. Rational in silico design identifies two mutations that restore UT28K SARS-CoV-2 monoclonal antibody activity against Omicron BA.1. Structure. 2024
Yoshiki Ikeda, Mindy I Davis, Kazutaka Sumita, Yuxiang Zheng, Satoshi Kofuji, Mika Sasaki, Yoshihisa Hirota, Rajan Pragani, Min Shen, Matthew B Boxer, et al. Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells. Biochemical and biophysical research communications. 2023. 679. 116-121
Yoshihiro Ueda, Koichiro Higasa, Yuji Kamioka, Naoyuki Kondo, Shunsuke Horitani, Yoshiki Ikeda, Wolfgang Bergmeier, Yoshinori Fukui, Tatsuo Kinashi. Rap1 organizes lymphocyte front-back polarity via RhoA signaling and talin1. iScience. 2023. 26. 8. 107292-107292
Hiroko Ueda, Quynh Thuy Huong Tran, Linh Nguyen Truc Tran, Koichiro Higasa, Yoshiki Ikeda, Naoyuki Kondo, Masaki Hashiyada, Chika Sato, Yoshinori Sato, Akira Ashida, et al. Characterization of cytoskeletal and structural effects of INF2 variants causing glomerulopathy and neuropathy. Scientific reports. 2023. 13. 1. 12003-12003
Yuji Kamioka, Yoshihiro Ueda, Naoyuki Kondo, Keizo Tokuhiro, Yoshiki Ikeda, Wolfgang Bergmeier, Tatsuo Kinashi. Distinct bidirectional regulation of LFA1 and α4β7 by Rap1 and integrin adaptors in T cells under shear flow. Cell Reports. 2023. 42. 6. 112580-112580

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MISC (6)：

池田幸樹, 竹田浩之, 木梨達雄. Novel method for quantification of interaction between Integrin and the binding partner. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
竹内恒, 池田幸樹, 千田美紀, 原田彩佳, 奥脇弘次, 福澤薫, 中川草, 長瀬里沙, 今井美咲, 廣田佳久, et al. Molecular evolution of PI5P4Kβ that underlies the GTP resilience. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
Yoshiki Ikeda, Tatsuo Kinashi. Drug discovery strategy for transmembrane proteins from the perspective of integrin drug discovery. SAR News. 2020. 39. 17-23
小藤智史, 小藤智史, 池田幸樹, WOLFE Kara, RANDHAWA Jaskirat, 河口理紗, 河口理紗, 島田裕子, 小藤香織, 佐々木美加, et al. がん特異的な代謝 7.GTP代謝. 実験医学. 2017. 35. 10. 1633-1641
S. Kofuji, M. Warren, K. Sumita, A. Ramkissoon, M. Sasaki, N. Majd, H. Yoshino, K. Kofuji, K. Okumura, Y. Ikeda, et al. GTP metabolic switch promotes malignant growth of brain tumors. MOLECULAR BIOLOGY OF THE CELL. 2015. 26

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Patents (5)：

Books (2)：

Lectures and oral presentations (24)：

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Professional career (1)：

Awards (2)：

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