- 2023 - 2027 Development of Organ- and Cell-specific In Vivo Genome Editing Technique as a Novel Approach for Cancer Gene Therapy
- 2023 - 2027 Development of Organ- and Cell-specific In Vivo Genome Editing Technique as a Novel Approach for Cancer Gene Therapy
- 2023 - 2026 Extracellular Vesicles Regulate Progressive Congestive Hepatopathy due to Heart Failure
- 2022 - 2025 Elucidation of the Mechanism of Regenerative Insufficiency in Advanced Liver Cirrhosis Caused by Intestinal Bacterial Extracellular Vesicles and Development of Prevention and Treatment Methods
- 2022 - 2025 Identification of malignant extracellular vesicles of liver origin that regulate nonalcoholic steatohepatitis and the development of the treatment
- 2022 - 2025 Development of novel treatment for non-alcoholic steatohepatitis by the research for the mechanism of regulation of liver fat accumulation
- 2022 - 2025 非アルコール性脂肪肝炎の病態を制御する肝臓由来の悪玉細胞外小胞の同定と治療法開発
- 2021 - 2024 Application of the Autonomic Nervous Management for NAFLD Treatment
- 2021 - 2024 遺伝子導入によるラット胆管癌モデルの確立と浸潤能評価による病態マーカー開発
- 2021 - 2024 Pancreatic cancer biomarker research by the exosome proteome analysis of the HGD rat pancreatic cancer model
- 2020 - 2024 Development of Hydrodynamics-based Gene Therapy for the Pancreatic Cancer
- 2021 - 2023 口腸連関における大腸がんリスクとなる潜在的粘膜親和性Pathobiont検索
- 2020 - 2023 診断困難な消化管運動異常症と機能性消化管疾患との境界症例の病態解明
- 2020 - 2023 Elucidation of Extracellular Vesicles Contributing Liver and Muscle Linkage
- 2020 - 2023 抗線維化・再生誘導剤の開発:臨床を見据えた肝硬変に対する間葉系幹細胞由来のエクソソームを用いた次世代治療法開発への基盤研究
- 2019 - 2022 Development of a treatment to improve fibrosis and elucidation of carcinogenesis mechanisms in improved NASH model MC4RKO mice
- 2019 - 2022 The study of emergence of cancerous gland in chronic gastritis through three dimensional histological structure and genetic analysis
- 2019 - 2022 間葉系幹細胞およびコラゲナーゼを用いた難治性食道狭窄に対する治療法の開発
- 2019 - 2022 Mechanisms of extrahepatic complications in NAFLD/NASH with focus on exosomes
- 2019 - 2022 Elucidation of regulatory function of the basal lamina fenestrations in intestinal villous epithelium for fat absorption.
- 2019 - 2021 Approaching the darkness of oral Helicobacter pylori: exploratory research on isolation / identification, infection mechanism, and persistent infection regulators
- 2018 - 2021 Development of novel anti-inflammatory therapy using mesenchymal stem cells
- 2018 - 2021 消化器発癌における免疫老化による免疫監視不全の関与の解明と新規先制医療の開発
- 2017 - 2021 肝臓特異的ハイドロダイナミック法による核酸医薬送達と肝癌遺伝子治療法への応用
- 2018 - 2020 Effect of Organ Communication on Liver Function upon the Liver Injury
- 2017 - 2020 Mechnism for improvemnt of pathophysiological condition in NASH treated with 7,8-Dihydroxyflavone
- 2016 - 2020 Establishment of the 3D minute blood vessel diagnostic method to esophageal cancer by the digital substance microscope fluorescence imaging
- 2017 - 2019 The Prevention of Fibrosis by the Elucidation of Interaction between Lymphoid Follicles and Activated Liver Stellate Cell.
- 2017 - 2019 The pathological role of secreted protein in promoting fibrosis in non alcoholic steatohepatitis.
- 2016 - 2019 Analysis of the basal lamina fenestrations in intestinal villous epithelium and the relation to the regulation of nutrient absorption
- 2016 - 2019 Efficacy of gelatin hydrogels incorporating triamcinolone acetonide for prevention of esohageal fibrosis after endoscopic submucosal dissection
- 2016 - 2019 Development of gene therapy for liver cirrhosis utilizing MMP13
- 2016 - 2018 Development of Medaka NASH Model and Hepatocarcinogenesis
- 2015 - 2018 Analysis of the factors of malignant behavior in hepatic progenitor cell marker expressing hepatocellular carcinoma
- 2014 - 2017 Basic research to develop next generation cell therapy for improvement of liver fibrosis.
- 2013 - 2016 Development of Medaka Model for Analysis of Angiogenesis and Kupffer cell
- 2012 - 2015 The analysis of small bone marrow drived liver repair cell
- 2012 - 2014 Development of the analytical method of the cancer stem cell using the ATP sensor in the cell
- 2011 - 2013 The development of new combination therapy with deferasirox and sorafenib on advanced hepatocellular carcinama
- 2011 - 2012 Basic research for chronotherapy focused on liver regeneration andliver steatosis by circadian clock
- 2010 - 2012 Both Herbal medicine Bofu-tsusho-san (TJ-62) and Dai-saiko-to (TJ-8) prevent liver fibrosis and hepatocarcinogenesis in rat liver cirrhosis.
- 2010 - 2012 The basic research of the development of future generation cell therapy used bone marrow derived liver repaid cell
- 2010 - 2011 Development of new gene transfer system for small fish
- 2009 - 2010 非アルコール性脂肪性肝炎関連発癌に対する戦略的研究
- 2008 - 2010 Development of a novel therapy using the iron chelator for advanced hepatocellular carcinoma
- 2008 - 2009 血管観察トランスジェニックメダカを用いた非アルコール性脂肪性肝炎の病態解析
- 2007 - 2009 Mechanism of fibrolysis and effect on cancer by autologus bone marrow cell infusion therapy for liver cirrhosis
- 2007 - 2008 The effect of Herbal medicine Bofu-tsusho-san(TJ-62)and the Crude Drugs with hepatic steatosis
- 2006 - 2007 癌幹細胞の発生分化制御機構の解析
- 2006 - 2007 Basic studies for the development of efficient liver regenerative therapy using bone marrow cells
- 2004 - 2006 Analysis of the serum factor which promotes the repopulation and differentiation of the bone marrow cell into hepatocyte.
- 2003 - 2004 骨髄細胞から肝細胞への分化を制御する遺伝子群の同定プロジェクト
- 2001 - 2003 The analysis for proliferation and differentiation of hepatic stem cells
- 2001 - 2002 骨髄血投与による肝臓リモデリングの基礎的検討
Show all