Rchr
J-GLOBAL ID：201801002790088175
Update date: Apr. 03, 2024
Takeshi Tokuyama
トクヤマ タケシ | Takeshi Tokuyama
Affiliation and department：
Job title：
Assistant professor
Research field (8)：
Medical biochemistry
, Molecular biology
, Cardiology
, Dermatology
, Cell biology
, Laboratory animal science
, Molecular biology
, Pathobiochemistry
Research keywords (6)：
iPS細胞由来心筋細胞
, ミトコンドリア機能評価(細胞・組織)
, Mitochondrial ubiquitin ligase MITOL / MARCH5
, Skin aging (photoaging / physiological aging)
, Myocardial infarction
, Mitochondria
Research theme for competitive and other funds (2)：
- 2022 - 2024 疾患iPS細胞を用いたBOLA3変異における膨状ミトコンドリアの病態意義の解明
- 2021 - 2023 ミトコンドリア動態に着目した心臓の生理的・病的老化の共通基盤の解明
Papers (17)：
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Tomohiro Hino, Satoshi N Omura, Ryoya Nakagawa, Tomoki Togashi, Satoru N Takeda, Takafumi Hiramoto, Satoshi Tasaka, Hisato Hirano, Takeshi Tokuyama, Hideki Uosaki, et al. An AsCas12f-based compact genome-editing tool derived by deep mutational scanning and structural analysis. Cell. 2023. 186. 22. 4920-4935
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Takeshi Tokuyama, Shigeru Yanagi. Role of Mitochondrial Dynamics in Heart Diseases. Genes. 2023. 14. 10
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Chika Watanabe, Hitoshi Osaka, Miyuki Watanabe, Akihiko Miyauchi, Eriko F Jimbo, Takeshi Tokuyama, Hideki Uosaki, Yoshihito Kishita, Yasushi Okazaki, Takanori Onuki, et al. Total and reduced/oxidized forms of coenzyme Q10 in fibroblasts of patients with mitochondrial disease. Molecular genetics and metabolism reports. 2023. 34. 100951-100951
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Razan E Ahmed, Takeshi Tokuyama, Tatsuya Anzai, Nawin Chanthra, Hideki Uosaki. Sarcomere maturation: function acquisition, molecular mechanism, and interplay with other organelles. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 2022. 377. 1864. 20210325-20210325
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Takeshi Tokuyama, Hideki Uosaki, Ayumu Sugiura, Gen Nishitai, Keisuke Takeda, Shun Nagashima, Isshin Shiiba, Naoki Ito, Taku Amo, Satoshi Mohri, et al. Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation. iScience. 2022. 25. 7. 104582-104582
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Patents (1)：
Education (2)：
- 2014 - 2017 Tokyo University of Pharmacy and Life Sciences Graduate School of Life Science
- 2012 - 2014 東京薬科大学大学院 生命科学研究科 生命科学研究科 博士前期課程 生命科学専攻
Professional career (1)：
- Ph.D. (Life Sciences (Tokyo University of Pharmacy and Life Sciences)
Work history (6)：
Awards (2)：
- 2016 - The 13th Conference of Asian Society for Mitochondrial Research and Medicine [ASMRM] and The 16th Conference of Japanese Society of Mitochondrial Research and Medicine [J-mit] Presentation Award
- 2015 - 第15回日本ミトコンドリア学会年会 若手優秀演題賞
Association Membership(s) (5)：
国際心臓研究会
, 日本循環器学会
, 日本分子生物学会
, 日本生化学学会
, 日本ミトコンドリア学会
