Rchr
J-GLOBAL ID：201801002960100396   Update date: Apr. 08, 2025

TAKEYUKI AKITA

アキタ タケユキ | TAKEYUKI AKITA
Affiliation and department：
Kyushu University Faculty of Pharmaceutical Sciences Department of Chemo-Pharmaceutical Sciences

About Kyushu University Faculty of Pharmaceutical Sciences Department of Chemo-Pharmaceutical Sciences


Job title： Lecturer
Research field  (5)： Structural/physical organic chemistry ,  Functional solid-state chemistry ,  Magnetism, superconductivity, and strongly correlated systems ,  Pharmaceuticals - chemistry and drug development ,  Pharmaceuticals - analytical and physicochemistry
Research theme for competitive and other funds  (13)：
  • 2022 - 2025 キラル・アキラル複合型固定相のテイラーメイドと二次元LCを用いる医療シーズ探索
  • 2022 - 2025 血液/尿中キラルアミノ酸の網羅的定量を基盤とする腎不全の早期低侵襲診断鑑別法開発
  • 2019 - 2022 Development of the three-dimensional LC system to realize quantitative chiral metabolomics for early diagnosis of kidney/heart disfunctions
  • 2019 - 2022 Development of a separation-field library for two-dimensional LC to drive dramatic progress of chiral metabolomics
  • 2009 - 2011 Magnetic Control of Reactions by Using of SPIONs
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Papers (50)：
  • Mai Oyaide, Takeyuki Akita, Chiharu Ishii, Masashi Mita, Kenji Hamase. Three-dimensional high-performance liquid chromatographic determination of serine, threonine and allothreonine enantiomers in mouse tissues and physiological fluids. Journal of Pharmaceutical and Biomedical Analysis Open. 2025. 5
  • ISHII Chiharu, KOGA Yumemi, FUJII Akira, AKITA Takeyuki, MITA Masashi, NAGANO Masanobu, HAMASE Kenji. Analysis of Alanine and Serine Enantiomers in Vinegars Using a Meter-long High-resolution Enantioselective Column. BUNSEKI KAGAKU. 2024. 73. 7.8. 337-344
  • Aogu Furusho, Chiharu Ishii, Takeyuki Akita, Mai Oyaide, Masashi Mita, Hiroshi Naraoka, Yoshinori Takano, Jason P. Dworkin, Yasuhiro Oba, Toshiki Koga, et al. Enantioselective three-dimensional high-performance liquid chromatographic determination of amino acids in the Hayabusa2 returned samples from the asteroid Ryugu. Journal of Chromatography Open. 2024. 5. 100134
  • Chiharu Ishii, Yosuke Tojo, Komei Iwasaki, Akira Fujii, Takeyuki Akita, Masanobu Nagano, Masashi Mita, Tomomi Ide, Kenji Hamase. Development of a two-dimensional LC-MS/MS system for the determination of proline and 4-hydroxyproline enantiomers in biological and food samples. Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry. 2024. 40. 5. 881-889
  • Chiharu Ishii, Takeyuki Akita, Tomonori Kimura, Shinsuke Sakai, Masashi Mita, Tomomi Ide, Yoshitaka Isaka, Kenji Hamase. Evaluation of individual variation of D-amino acids in human plasma by a two-dimensional LC-MS/MS system and application to the early diagnosis of chronic kidney disease. Analytical Chemistry. 2024. 96. 12. 4876-4883
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MISC (68)：
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Lectures and oral presentations  (219)：
  • 老化・劣化タンパク質中の異性化アミノ酸解析を可能とする二次元キラルLC-MS/MS法開発
    (日本薬学会第144年会 2024)
  • ヒト体液中親水性D-アミノ酸の二次元HPLC分析と発酵食品摂取による影響
    (日本薬学会第144年会 2024)
  • 各種哺乳動物における尿中疎水性アミノ酸のキラル識別分析
    (日本薬学会第144年会 2024)
  • グリシンおよび酸性アミノ酸を含有するジペプチドを対象とした二次元キラルHPLC分析法の開発
    (日本薬学会第144年会 2024)
  • アラニン、アスパラギン酸、セリン、乳酸および3-ヒドロキシ酪酸を対象とする二次元キラルHPLC法開発とヒト生体液試料の分析
    (第34回クロマトグラフィー科学会議 2023)
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