Rchr
J-GLOBAL ID:201801003283798353
Update date: Oct. 18, 2024
WATANABE Takayasu
ワタナベ タカヤス | WATANABE Takayasu
Affiliation and department:
Job title:
Lecturer
Research field (4):
Regenerative dentistry and dental engineering
, Conservative dentistry and endodontics
, Conservative dentistry and endodontics
, Oral medicine
Research keywords (3):
Microbiota
, Genome
, Oral bacteria
Research theme for competitive and other funds (16):
- 2024 - 2028 インプラント周囲炎に対するミノサイクリン治療効果の細菌叢エビデンス構築
- 2022 - 2025 インプラント周囲細菌叢を規定する危険因子を探る:疾患の発症予測モデル構築に向けて
- 2020 - 2023 Clarification of virulence factor involved in the chronicity of osteomyelitis of the jaw
- 2020 - 2023 Elucidation of the pathogenicity and formation process of bacterial network triggered periodontal diseases
- 2020 - 2023 短鎖連続塩基配列に基づく細菌ゲノム・菌叢解析と機械学習による口臭予測への応用
- 2020 - 2023 Investigation of transcriptional activity of microbiota for causing peri-implantitis
- 2018 - 2022 Spatio-temporal surveillance of peri-implant microbiota
- 2020 - 2021 人工知能を駆使した口腔細菌叢CRISPRによる歯周病発症予測の基盤構築
- 2017 - 2019 Hologenome analyses of microbiota in periodontitis and peri-implantitis
- 2016 - 2019 Analysis of collaborative activities between the capsule-positive and capsule-negative Streptococcus suis in the induction of and escape from autophagy
- 2016 - 2019 Metagenomic analysis of microbiota within chicken intestinal tract and environment for prevention of Campylobacter spread to chicken meat
- 2015 - 2019 Analysis of porcine oral flora dynamics for determining the main cause of developing swine streptococcosis
- 2018 - 歯周炎局所の細菌叢データにおける歯周病原細菌の未知なる免疫記憶領域探索
- 2014 - 2016 高頻度ゲノム変異がもたらす歯周病原細菌の病原性変換メカニズム
- 2014 - 2016 Cooperative and competitive interactions among periodontal pathogens
- 2012 - 2013 歯周病原性細菌の新規ゲノム多様化機構と口腔内生存戦略
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Papers (36):
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Nagai T, Shiba T, Komatsu K, Watanabe T, Nemoto T, Maekawa S, Kobayashi R, Matsumura S, Ohsugi Y, Katagiri S, et al. Optimal 16S rRNA gene amplicon sequencing analysis for oral microbiota to avoid the potential bias introduced by trimming length, primer, and database. Spectrum. 2024. in press
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Uemichi K, Mikami Y, Watanabe T, Shinozuka K, Tonogi M, Tsuda H. Histone-deacetylase-inhibitory effects of periodontopathic-bacterial metabolites induce human gingival epithelial Ca9-22 cell death. Odontology. 2023. 111. 658-667
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Shiba T†, Komatsu K†, Watanabe T†, Takeuchi Y, Nemoto T, Ohsugi Y, Katagiri S, Shimogishi M, Marukawa E, Iwata T. Peri-implantitis management by resective surgery combined with implantoplasty and Er:YAG laser irradiation, accompanied by free gingival graft: a case report. Ther Adv Chronic Dis. 2023. 14. 20406223231174800
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渡辺孝康, 芝多佳彦, 中野善夫. Detection of dysbiosis within oral microbiota by using artificial intelligence and CRISPR. 日大歯紀. 2021. 49. 1-6
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Nemoto T, Shiba T, Komatsu K, Watanabe T, Shimogishi M, Shibasaki M, Koyanagi T, Nagai T, Katagiri S, Takeuchi Y, et al. Discrimination of bacterial community structure among healthy, gingivitis, and periodontitis statuses through integrated metatranscriptomic and network analyses. mSystems. 2021. 6. 6. e00886-21
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MISC (6):
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Watanabe T. Compositional change within peri-implant microbiota after implant uncovering (Reprinted from Precision Medicine, 2024 Jan.). BIO Clinica. 2024. 39. 10. 62(870)-65(873)
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Watanabe T. Compositional change within peri-implant microbiota after implant uncovering. Precision Medicine. 2024. 7. 1. 47-50
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Watanabe T. Analysis of human oral microbiota: an overview and its application. J Pet Anim Nutr. 2018. 21. 3. 154-157
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芝多佳彦, 竹内康雄, 渡辺孝康, 小柳達郎, 丸山緑子, 加地博一, 村瀬一典, 丸山史人, 中川一路, 和泉雄一. インプラント周囲炎と歯周炎の細菌学的な違いを科学する. 歯界展望. 2017. 129. 5. 823-826
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Watanabe T, Murase K, Nakagawa I, Maruyama F. Highlighting genome evolution by a novel acquired immunity system in prokaryotes. Antibiotics & Chemotherapy. 2015. 31. 11. 118(2240)-128(2250)
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Books (3):
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The Oral Microbiome
Methods in Molecular Biology, Springer International Publishing 2021 ISBN:9781071615171
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Risk Factors for Peri-implant Diseases
Springer International Publishing 2020 ISBN:9783030391843
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<I>Streptococcus pyogenes</I>, Basic Biology to Clinical Manifestations
NIH NCBI Bookshelf 2016
Lectures and oral presentations (118):
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インプラント周囲細菌叢を規定するリスク因子の検討
(第26回日本顎顔面インプラント学会総会・学術大会 2022)
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古代人の歯石DNAを用いた江戸時代と現代の網羅的口腔内細菌叢解析
(第76回日本人類学会大会・第38回日本霊長類学会大会連合大会 2022)
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メタゲノム16S解析法を用いた難治性根尖性歯周炎症例における摘出検体の細菌叢解析
(第156回日本歯科保存学会学術大会(春季) 2022)
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インプラント周囲粘膜における遊離歯肉移植術が及ぼす細菌叢の変化
(第25回日本顎顔面インプラント学会総会・学術大会 2021)
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深層学習による歯周炎・インプラント周囲炎の識別方法の検討
(第63回歯科基礎医学会学術大会 2021)
more...
Education (2):
- 2009 - 2013 Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences Department of Bacterial Pathogenesis Doctoral Program
- 2002 - 2008 Tokyo Medical and Dental University Faculty of Dentistry School of Dentistry
Professional career (1):
- DDS, PhD (Tokyo Medical and Dental University)
Work history (8):
- 2022/04 - 現在 Nihon University School of Dentistry Department of Chemistry Lecturer
- 2019/10 - 現在 Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences Part-time Lecturer
- 2018/04 - 2022/03 Nihon University School of Dentistry Department of Chemistry Assistant Professor
- 2017/04 - 2018/03 日本大学 歯学部 基礎自然科学分野(化学) 兼任講師
- 2015/06 - 2018/03 The University of Tokyo, Graduate School of Agricultural and Life Sciences Laboratory of Food-borne Pathogenic Microbiology Project Assistant Professor
- 2014/04 - 2015/06 Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences Department of Periodontology JSPS Research Fellow PD
- 2012/04 - 2014/03 Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences Department of Bacterial Pathogenesis JSPS Research Fellow DC2
- 2008/04 - 2009/03 Tokyo Medical and Dental University Dental Hospital Dental Resident
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Committee career (1):
- 2018 - 2020 東京大学大学院農学生命科学総合研究科 JRA畜産振興事業推進委員
Awards (5):
- 2019/11 - Excellent Poster Award, 150th Meeting of the Japanese Society of Conservative Dentistry 網羅的な細菌叢解析による歯周炎とインプラント周囲炎の菌叢構造比較
- 2014/03 - Excellent Presentation Award, 87th Annual Meeting of Japanese Society for Bacteriology
- 2013/03 - Award of Kobayashi Scholarship Society (selected from PhD students in Tokyo Medical and Dental University)
- 2012/03 - Excellent Posters Prize, 85th Annual Meeting of Japanese Society for Bacteriology
- 2006 - Award of Kobayashi Scholarship Society (selected as Excellent Presentation Award of Research Training in Tokyo Medical and Dental University Faculty of Dentistry)
Association Membership(s) (5):
JAPANESE DENTAL EDUCATION ASSOCIATION
, JAPANESE ASSOCIATION FOR ORAL BIOLOGY
, 日本大学歯学会
, Japanese Academy of Maxillofacial Implants
, Japanese Society of Conservative Dentistry
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