Rchr
J-GLOBAL ID：201801003473180470
Update date: Oct. 09, 2024
Kamagata Kiyoto
カマガタ キヨト | Kamagata Kiyoto
Affiliation and department：
Job title：
Associate professor
Homepage URL (1)：
https://www.eng.gifu-u.ac.jp/seimei/staff/k-kamagata.html
Research field (1)：
Biophysics
Research keywords (13)：
single molecule imaging
, DNA binding protein
, DNA整列固定技術
, 液液相分離
, function
, DNA
, intrinsically disordered protein
, p53
, ゲノム編集
, タンパク質工学
, ペプチド
, 合理的設計
, 創薬
Research theme for competitive and other funds (21)：
- 2024 - 2026 液滴形成を制御する非ドメイン型タンパク質の探索と液滴内単分子機能解析
- 2022 - 2024 液-液相分離を制御する非ドメイン型タンパク質の探索と単分子機能解析
- 2021 - 2023 相分離タンパク凝集体をほぐす人工タンパク質の合理的設計
- 2020 - 2023 Rational design of genome editing protein toward fast and accurate editing
- 2019 - 2022 Effects on p53 diffusion along dsDNA and nonspecific binding constant between p53 and dsDNA of hyper-mobile water control
- 2016 - 2019 Development of micro second measurement for functional analysis of DNA binding proteins
- 2016 - 2019 Computational design of novel proteins with weak interactions
- 2017 - 2019 Single-molecule analysis of DNA binding proteins using DNA array(Fostering Joint International Research)
- 2017 - 2019 DNA整列固定技術を用いたDNA結合蛋白質の網羅的単分子機能解析
- 2013 - 2018 Investigation on the dynamics of protein folding by single molecule fluorescence spectroscopy
- 2016 - 2018 DNA結合蛋白質の機能解析のためのマイクロ秒時分割単分子計測技術の創出
- 2015 - 2017 蛋白質の構造変化を自在に操作する技術の創出-トランスポーターへの応用-
- 2014 - 2016 Development of ultrafast detection system for the single molecule fluorescence based on hybrid photo detector
- 2014 - 2016 Single-molecule characterization of target DNA search of tumor suppressor p53
- 2015 - 2016 蛋白質の構造変化を自在に操作する技術の創出-トランスポーターへの応用-
- 2012 - 2014 天然変性タンパク質p53の一分子構造・構造揺らぎ解析法の開発
- 2011 - 2012 Development of microfluidic cell based on light guide for the single molecule fluorescence measurements
- 2010 - 2011 変性タンパク質の動的多様構造の新規解析法の開発
- 2009 - 2011 Investigation of the folding dynamics of proteins based on the advanced method of single molecule detection
- 2009 - 2010 Ligand recognition of intrinsically disordered protein revealed by a new single-molecule measurement
- 2004 - 2005 高圧下温度ジャンプ装置によるシクロフィリンの素早い折れたたみ機構の研究
Show all
Papers (46)：
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Trishit Banerjee, K Geethika, Saori Kanbayashi, Satoshi Takahashi, Soumit S Mandal, Kiyoto Kamagata. Thermostable nucleoid protein Cren7 slides along DNA and rapidly dissociates from DNA while not inhibiting the sliding of other DNA-binding protein. Journal of molecular biology. 2024. 168803-168803
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Kiyoto Kamagata, Ryo Kusano, Saori Kanbayashi, Trishit Banerjee, Hiroto Takahashi. Single-molecule characterization of target search dynamics of DNA-binding proteins in DNA-condensed droplets. Nucleic acids research. 2023. 51. 6654-6667
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Kiyoto Kamagata, Saori Kanbayashi, Shuichi Koda, Akito Kadotani, Osamu Ubukata, Takumi Tashima. Suppression of TDP-43 aggregation by artificial peptide binder targeting to its low complexity domain. Biochemical and biophysical research communications. 2023. 662. 119-125
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Kiyoto Kamagata, Atsumi Hando, Maulana Ariefai, Nanako Iwaki, Saori Kanbayashi, Ryotaro Koike, Keisuke Ikeda. Rational design of phase separating peptides based on phase separating protein sequence of p53. Scientific reports. 2023. 13. 1. 5648-5648
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Kiyoto Kamagata, Maulana Ariefai, Hiroto Takahashi, Atsumi Hando, Dwiky Rendra Graha Subekti, Keisuke Ikeda, Atsushi Hirano, Tomoshi Kameda. Rational peptide design for regulating liquid-liquid phase separation on the basis of residue-residue contact energy. Scientific reports. 2022. 12. 1. 13718-13718
ｍore...
MISC (21)：
Books (3)：
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P53 - A Guardian of the Genome and Beyond "A Study of p53 Action on DNA at the Single Molecule Level"
IntechOpen 2021
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相分離生物学の全貌 26章「がん抑制タンパク質p53の液ー液相分離」
東京化学同人 2020 ISBN:9784807913466
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揺らぎ・ダイナミクスと生体機能 : 物理化学的視点から見た生体分子 4.1, 4.2章 「一分子計測」
化学同人 2013 ISBN:9784759815108
Lectures and oral presentations (85)：
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タンパク質液滴を測り、操り、創る
(新領域開拓課題「一分子の科学」合同合宿セミナー 2024)
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Watching, Manipulating, and Creating Protein Droplets
(The 8th LLPS Symposium/ The Biophysical Society of Japan Joint Seminar 2024)
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Liquid-liquid phase separation of tumor suppressor p53
(2024)
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がん抑制タンパク質p53の液-液相分離に関する生物物理学的研究
(第32回日本Cell Death学会学術集会 2024)
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Elucidating fusion dynamics of FUS protein droplets using fluorescence microscopy and optical tweezers
(IUPAB 2024 2024)
ｍore...
Professional career (1)：
Work history (5)：
- 2024/04 - 現在 Gifu University Faculty of Engineering Associate professor
- 2018/10 - 2024/03 Tohoku University Institute of Multidisciplinary Research for Advanced Materials
- 2009/04 - 2018/09 Tohoku University Institute of Multidisciplinary Research for Advanced Materials
- 2006/04 - 2009/03 Osaka University Institute for Protein Research
- 2005/04 - 2006/03 The University of Tokyo
Awards (1)：
Association Membership(s) (3)：
アメリカ生物物理学会
, PROTEIN SCIENCE SOCIETY OF JAPAN
, THE BIOPHYSICAL SOCIETY OF JAPAN
