Rchr
J-GLOBAL ID：201801003755125277
Update date: Feb. 01, 2024
Hibino Sana
Hibino Sana
Affiliation and department：
Research field (2)：
Immunology
, Pathobiochemistry
Research keywords (3)：
immune tolerance
, T cell
, cancer immunology
Research theme for competitive and other funds (7)：
Papers (15)：
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Miki Kato, Keisuke Maeda, Ryuichi Nakahara, Haruka Hirose, Ayano Kondo, Sho Aki, Maki Sugaya, Sana Hibino, Miyuki Nishida, Manami Hasegawa, et al. Acidic extracellular pH drives accumulation of N1-acetylspermidine and recruitment of protumor neutrophils. PNAS nexus. 2023. 2. 10. pgad306
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Sana Hibino, Shotaro Eto, Sho Hangai, Keiko Endo, Sanae Ashitani, Maki Sugaya, Tsuyoshi Osawa, Tomoyoshi Soga, Tadatsugu Taniguchi, Hideyuki Yanai. Tumor cell-derived spermidine is an oncometabolite that suppresses TCR clustering for intratumoral CD8+ T cell activation. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 24. e2305245120
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Sho Hangai, Takeshi Kawamura, Yoshitaka Kimura, Ching-Yun Chang, Sana Hibino, Daisuke Yamamoto, Yousuke Nakai, Ryosuke Tateishi, Masanobu Oshima, Hiroko Oshima, et al. Orchestration of myeloid-derived suppressor cells in the tumor microenvironment by ubiquitous cellular protein TCTP released by tumor cells. Nature immunology. 2021. 22. 8. 947-957
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Sana Hibino, Tetsuro Kawazoe, Hidenori Kasahara, Shinji Itoh, Takatsugu Ishimoto, Mamiko Sakata-Yanagimoto, Koji Taniguchi. Inflammation-Induced Tumorigenesis and Metastasis. International journal of molecular sciences. 2021. 22. 11
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Naoyuki Senda, Hideyuki Yanai, Sana Hibino, Lei Li, Yu Mizushima, Tomomitsu Miyagaki, Mai Saeki, Yusuke Kishi, Sho Hangai, Junko Nishio, et al. HMGB1-mediated chromatin remodeling attenuates Il24 gene expression for the protection from allergic contact dermatitis. Proceedings of the National Academy of Sciences of the United States of America. 2021. 118. 1
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MISC (4)：
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柳井秀元, 日比野沙奈, 衞藤翔太郎, 半谷匠. Immunosuppression associated with tumor development. 月刊臨床免疫・アレルギー科. 2023. 79. 6
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吉村 昭彦, 日比野 沙奈, 染谷 和江, 岡田 匡央. 【炎症-全体像を知り慢性疾患を制御する 炎症シグナル、免疫細胞のダイナミズムからがん・糖尿病などの発症機序と治療標的まで】 (第1章)炎症応答の時・空間的ダイナミクスと関与する細胞たち サイトカインによるヘルパーT細胞分化制御. 実験医学. 2014. 32. 17. 2734-2741
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吉村 昭彦, 日比野 沙奈, 染谷 和江, 知念 孝敏. 【樹状細胞の機能制御】 樹状細胞における炎症性サイトカイン産生抑制機構. 臨床免疫・アレルギー科. 2014. 61. 2. 135-140
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染谷 和江, 日比野 沙奈, 吉村 昭彦. 【炎症の抑制・終焉機構】 核内受容体Nr4aとTGF-βによる制御性T細胞の発生制御. 炎症と免疫. 2014. 22. 2. 73-78
Lectures and oral presentations (15)：
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ネクローシス癌細胞の代謝物セクレトームが,癌におけるT細胞の機能不全に関与する
(日本癌学会学術総会抄録集(Web) 2021)
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Oncometabolite released from necrotic tumor cells acts as a checkpoint regulator for T cell function
(日本癌学会学術総会抄録集(Web) 2020)
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ネクローシス癌細胞が放出するオンコメタボライトによる,抗腫瘍T細胞免疫応答の制御メカニズムの解明
(日本がん免疫学会総会プログラム・抄録集 2020)
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Inhibition of Nr4a receptors enhances anti-tumor immunity by breaking Treg-mediated immune tolerance.
(2018)
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Inhibition of Nr4a receptors breaks Treg-mediated suppression of anti-tumor immunity.
(Cytokines 2017 2017)
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Education (2)：
- 2014 - 2018 Keio University School of Medicine Microbiology and Immunology
- 2008 - 2014 Keio University Faculty of Pharmacy
Professional career (1)：
Work history (5)：
- 2023/07 - 現在 国立研究開発法人国立がん研究センター 腫瘍免疫研究分野 特任研究員
- 2022/04 - 2023/06 東京大学 先端科学技術研究センター 特任研究員
- 2019/04 - 2022/03 The University of Tokyo Research Center for Advanced Science and Technology
- 2018/04 - 2019/03 The University of Tokyo Institute of Industrial Science
- 2015/04 - 2018/03 Keio University School of Medicine
Awards (1)：
- 2019/09 - LEGEND Research Grant Program 2019(前期)
Association Membership(s) (2)：
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