Rchr
J-GLOBAL ID:201801003826424580   Update date: Nov. 22, 2024

Takemura Naoki

タケムラ ナオキ | Takemura Naoki
Affiliation and department:
Research field  (4): Immunology ,  Environmental effects of chemicals ,  Laboratory animal science ,  Food sciences
Research keywords  (7): 自然免疫 ,  粘膜免疫 ,  自然炎症 ,  バリア組織障害 ,  細胞死 ,  メタボリックシンドローム ,  機能性食品
Research theme for competitive and other funds  (4):
  • 2024 - 2027 吸入性微粒子による細胞死と呼吸器疾患を繋ぐ新たな分子メカニズムの解明
  • 2021 - 2023 Evaluation of micro- and nano-sized plastics as a risk factor for food allergy
  • 2016 - 2020 Development of prophylactic strategies for acute and chronic radiation-induced gastrointestinal syndrome by targeting the innate immune system
  • 2013 - 2016 Study on the role of TLR3 in radiation-induced gastrointestinal syndrome
Papers (46):
  • Sota Kidawara, Shizuki Kimura, Haruka Takano, Wakana Inoue, Kota Iinuma, Michihiro Takahama, Naoki Takemura, Tatsuya Saitoh. Oridonin Suppresses Mast Cell Degranulation and Alleviates Ovalbumin-Induced Allergic Rhinitis. Biological and Pharmaceutical Bulletin. 2024. 47. 11. 1920-1926
  • Atsushi Kawai, Masahiro Noda, Haruki Hirata, Lisa Munakata, Teppei Matsuda, Daiki Omata, Naoki Takemura, Sakura Onoe, Mika Hirose, Takayuki Kato, et al. Lipid Nanoparticle with 1,2-Di-O-octadecenyl-3-trimethylammonium-propane as a Component Lipid Confers Potent Responses of Th1 Cells and Antibody against Vaccine Antigen. ACS Nano. 2024. 18. 26. 16589-16609
  • Naoki Takemura. Development of anti-inflammatory drugs with novel mechanisms of action targeting pyroptosis. YAKUGAKU ZASSHI. 2023. 143. 12. 997-1003
  • Yixi Pan, Kenta Ikoma, Risa Matsui, Akiyoshi Nakayama, Naoki Takemura, Tatsuya Saitoh. Dasatinib suppresses particulate-induced pyroptosis and acute lung inflammation. Frontiers in Pharmacology. 2023. 14. 1250383
  • Yudai Matsui, Naoki Takemura, Yoshitaka Shirasaki, Michihiro Takahama, Yoshihiko Noguchi, Kenta Ikoma, Yixi Pan, Shuhei Nishida, Manabu Taura, Akiyoshi Nakayama, et al. Nanaomycin E inhibits NLRP3 inflammasome activation by preventing mitochondrial dysfunction. International Immunology. 2022. 34. 10. 505-518
more...
MISC (20):
  • Naoki Takemura, Tatsuya Saitoh. NOD-like receptors. Thrombosis Medicine. 2024. 14. 3. 56-60
  • Naoki Takemura, Tatsuya Saitoh. Cell death and sterile inflammation; The pathological roles of particulate matter-induced pyroptosis. Clinical immunology & allergology. 2023. 80. 1. 63-69
  • Naoki Takemura, Tatsuya Saitoh. Sterile inflammation driven by pyroptosis and its regulation: Development of new anti-inflammatory drugs targeting organelles. Journal of clinical and experimental medicine. 2022. 283. 5. 455-462
  • 田浦学, 武村直紀, 齊藤達哉. PRRを介した炎症反応における細胞骨格の役割. 臨床免疫・アレルギー科. 2021. 76. 6. 614-621
  • 武村 直紀, 齊藤 達哉. 痛風発症におけるNLRP3インフラマソームの役割. 高尿酸血症と痛風. 2020. 28. 1. 6-10
more...
Patents (3):
  • 放射線障害の治療又は予防剤ならびに治療又は治療方法
  • ワクチン用アジュバント、ワクチン、及び免疫誘導方法
  • 放射線誘導性消化管症候群の予防又は治療用医薬組成物
Books (2):
  • 標準生理学 第9版
    医学書院 2019 ISBN:9784260034296
  • 次世代アジュバント開発のためのメカニズム解明と安全性評価
    シーエムシー出版 2017 ISBN:9784781312385
Lectures and oral presentations  (90):
  • mRNAワクチンにおける副反応誘導メカニズムの解析
    (第28回日本ワクチン学会 2024)
  • 微粒子により誘導されるリソソームエキソサイトーシスの解析
    (第74回日本薬学会関西支部総会・大会 2024)
  • 皮膚傷害に伴い放出される免疫制御分子のプロテオーム解析
    (第74回日本薬学会関西支部総会・大会 2024)
  • Immunological mechanism of intranasal adenovirus vaccine-induced effects via IL-1 signaling
    (2024)
  • Vitamin D3代謝体secalciferolによる自然免疫における抗炎症効果の解析
    (日本ビタミン学会第76回大会 2024)
more...
Education (3):
  • 2007 - 2010 Hokkaido Univsersity Graduate School of Life Science Biosystems Science Course
  • 2005 - 2007 Hokkaido Univsersity Graduate School of Agriculture Division of Applied Bioscience
  • 2001 - 2005 Hokkaido Univsersity Faculty of Agriculture Research Group of Bioscience and Chemistry
Professional career (1):
  • 生命科学 (北海道大学)
Work history (6):
  • 2022/09 - 現在 Osaka University Graduate School of Pharmaceutical Sciences Medical Pharmacy Associate Professor
  • 2019/03 - 2022/08 Osaka university Laboratory of Bioresponse Regulation, Graduate School of Pharmaceutical Sciences Lecturer
  • 2015/10 - 2019/02 Chiba University Department of Mucosal Immunology, School of Medicine Lecturer
  • 2012/10 - 2018/07 Institute of Medical Science, The University of Tokyo Division of Innate Immune Regulation, International Research and Development Center for Mucosal Vaccines Project Assistant Professor
  • 2014/08 - 2015/10 Chiba University Department of Mucosal Immunology, School of Medicine Project Assistant Professor
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Committee career (2):
  • 2019/04 - 現在 日本薬学会 日本薬学会関西支部委員
  • 2024/09 - 日本免疫毒性学会 評議員
Awards (8):
  • 2022/12 - 日本薬学会関西支部 奨励賞
  • 2019/07 - International Eosinophil Society, Inc. Gerald J. Gleich Lectureship Award
  • 2016/12 - 日本免疫学会 ベストプレゼンテーション賞
  • 2015/12 - 日本免疫学会 SMI-MI Award for Mucosal Immunology
  • 2015/06 - 東京大学医科学研究所 創立記念ベストポスター賞
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Association Membership(s) (7):
JAPANESE ASSOCIATION FOR DIETARY FIBER RESEARCH ,  THE JAPANESE ASSOCIATION OF FOOD IMMUNOLOGY ,  JAPAN SOCIETY OF NUTRITION AND FOOD SCIENCE ,  JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY ,  THE JAPANESE SOCIETY FOR IMMUNOLOGY ,  The Japanese Society of Immunotoxicology ,  THE PHARMACEUTICAL SOCIETY OF JAPAN
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