Rchr
J-GLOBAL ID：201801003864476578
Update date: Mar. 07, 2024
Kei Otsuka
Kei Otsuka
Affiliation and department：
Research field (1)：
Developmental biology
Research keywords (3)：
生殖細胞
, 発生
, 腫瘍生物学
Research theme for competitive and other funds (3)：
- 2019 - 2022 Elucidation of carcinogenesis by dysregulation of the centrosome by BRCA1/BARD1
- 2019 - 2022 Development of Targeting therapy for centrosome dysregulation in cancer
- 2019 - 2021 若手研究
Papers (14)：
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Ayano Moriya, Kei Otsuka, Riku Naoi, Mayu Terahata, Koji Takeda, Shu Kondo, Takashi Adachi-Yamada. Creation of Knock-In Alleles of Insulin Receptor Tagged by Fluorescent Proteins mCherry or EYFP in Fruit Fly Drosophila melanogaster. Zoological Science. 2024. 41. 2
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Zhenzhou Fang, Xingming Li, Yuki Yoshino, Moe Suzuki, Huicheng Qi, Hinari Murooka, Riko Katakai, Matsuyuki Shirota, Thi Anh Mai Pham, Ayako Matsuzawa, et al. Aurora A polyubiquitinates the BRCA1-interacting protein OLA1 to promote centrosome maturation. Cell reports. 2023. 42. 8. 112850-112850
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Hitoshi Sawada, Shukumi Inoue, Takako Saito, Kei Otsuka, Maki Shirae-Kurabayashi. Involvement in Fertilization and Expression of Gamete Ubiquitin-Activating Enzymes UBA1 and UBA6 in the Ascidian Halocynthia roretzi. International Journal of Molecular Sciences. 2023. 24. 13. 10662-10662
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Huicheng Qi, Megumi Kikuchi, Yuki Yoshino, Zhenzhou Fang, Kazune Ohashi, Takato Gotoh, Ryo Ideta, Ayako Ui, Shino Endo, Kei Otsuka, et al. BRCA1 transports the DNA damage signal for CDDP-induced centrosome amplification through the centrosomal Aurora A. Cancer science. 2022. 113. 12. 4230-4243
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Kei Otsuka, Yuki Yoshino, Huicheng Qi, Natsuko Chiba. The Function of BARD1 in Centrosome Regulation in Cooperation with BRCA1/OLA1/RACK1. Genes. 2020. 11. 8
ｍore...
MISC (1)：
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Hayashi Y, Otsuka K, Ebina M, Igarashi K, Takehara A, Matsumoto M, Kanai A, Igarashi K, Soga T, Matsui Y. Correction: Distinct requirements for energy metabolism in mouse primordial germ cells and their reprogramming to embryonic germ cells (Proceedings of the National Academy of Sciences of the United States of America (2017) 114 (8289-8294) DOI: 10.1073/pna. Proceedings of the National Academy of Sciences of the United States of America. 2018. 115. 30
Books (1)：
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Sexual Reproduction in Animals and Plants
Springer 2014
Professional career (1)：
Work history (4)：
- 2022/04 - 現在 Gakushuin University
- 2018/04 - 2022/03 Tohoku University Institute of Development, Aging and Cancer
- 2015/06 - 2018/03 Tohoku University Institute of Development, Aging and Cancer
- 2015/04 - 2015/05 Nagoya University Graduate School of Science
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