Yoshitomi Yasuo

ヨシトミヤスオ | Yoshitomi Yasuo

Research field (1)： Developmental biology

Research theme for competitive and other funds (8)：

2022 - 2026 コラーゲン・トリペプチドの血管保護作用の機序解明と疾病に対する予防治療効果の検証
2022 - 2025 メカノセンサーPiezo1-JunBシグナルが制御する血管リモデリング機構の解明
2021 - 2024 敗血症における血管内皮細胞で産生されるsFlt-1の役割の解明
2019 - 2023 紫外線暴露により水晶体で発現誘導されるOtx2の白内障発症における役割の解明
2019 - 2022 Basic research for the development of artificial perifascial areolar tissue

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Papers (22)：

Hidehito Saito-Takatsuji, Yasuo Yoshitomi, Ryo Yamamoto, Takafumi Furuyama, Yasuhito Ishigaki, Nobuo Kato, Hideto Yonekura, Takayuki Ikeda. Transthyretin Is Commonly Upregulated in the Hippocampus of Two Stress-Induced Depression Mouse Models. International journal of molecular sciences. 2023. 24. 4
Craig S. Rhodes, Yasuo Yoshitomi, Peter D. Burbelo, Nowlan H. Freese, Takashi Nakamura, Yuta Chiba, Yoshihiko Yamada. Sp6/Epiprofin is a master regulator in the developing tooth. Biochemical and Biophysical Research Communications. 2021. 581. 89-95
Takayuki Ikeda, Yoshino Yoshitake, Yasuo Yoshitomi, Hidehito Saito-Takatsuji, Yasuhito Ishigaki, Hideto Yonekura. EPAC2 acts as a negative regulator in Matrigel-driven tubulogenesis of human microvascular endothelial cells. Scientific Reports. 2021. 11. 1. 19453-19453
Hidehito Saito-Takatsuji, Yasuo Yoshitomi, Yasuhito Ishigaki, Shoko Yamamoto, Noriaki Numata, Yasuo Sakai, Masayoshi Takeuchi, Naohisa Tomosugi, Shogo Katsuda, Hideto Yonekura, et al. Protective Effects of Collagen Tripeptides in Human Aortic Endothelial Cells by Restoring ROS-Induced Transcriptional Repression. Nutrients. 2021. 13. 7
Shinsuke Shibata, Naoko Shibata, Satoshi Ohtsuka, Yasuo Yoshitomi, Etsuko Kiyokawa, Hideto Yonekura, Dhirendra P. Singh, Hiroshi Sasaki, Eri Kubo. Role of Decorin in Posterior Capsule Opacification and Eye Lens Development. Cells. 2021. 10. 4. 863-863

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MISC (5)：

Y. Yoshitake, T. Ikeda, Y. Yoshitomi, H. Yonekura. Increased expression of Epac2 during in vitro tube formation of human microvascular endothelial cells. FEBS JOURNAL. 2012. 279. 174-174
T. Ikeda, Y. Yoshitomi, Y. Ishigaki, Y. Yoshitake, H. Yonekura. Hypoxia down-regulates sFlt-1 (sVEGFR-1) expression in human microvascular endothelial cells by a mechanism involving mRNA alternative processing. FEBS JOURNAL. 2011. 278. 86-86
Y. Yoshitake, H. Osada, T. Ikeda, Y. Yoshitomi, Y. Ishigaki, H. Sasaki, H. Yonekura. Ultraviolet B-induced expression of amphiregulin and growth differentiation factor 15 in human lens epithelial cells. FEBS JOURNAL. 2011. 278. 191-191
Yasuo Yoshitomi, Hideaki Naruo, Selichi Munesue, Yoshie Koyama, Shinsuke Kiyono, Katsunori Hashimoto, Toyoharu Yokoi, Satoru Shimizu, Kayoko Oguri, Minoru Okayama. Participation of glypican-tike proteoglycans in localization of MMP-9 on the cell surface of colon carcinoma cells. CLINICAL & EXPERIMENTAL METASTASIS. 2007. 24. 4. 253-253
Seiichi Munesue, Yasuo Yoshitomi, Yoshie Koyama, Shinsuke Kiyono, Kayoko Oguri, Hayao Nakanishi, Satoru Shimizu, Minoru Okayama. Regulation of MMP-2 activation by syndecan-2 through its heparan sulfate side chains in Lewis lung carcinoma cells. CLINICAL & EXPERIMENTAL METASTASIS. 2007. 24. 4. 250-250

Lectures and oral presentations (33)：

皮膚全層欠損創に対するデコリンの創収縮抑制効果
(第99回北陸形成外科学会 2023)
うつモデルマウスの脳海馬で発現変動する遺伝子の探索と役割の解明
(第39回分子病理研究会 2022)
Role of Tip cell transcription factor JunB in the vascular network development
(MBSJ2021 2021)
Decorin過剰発現がマウス水晶体組織に与える影響
(第75回日本臨床眼科学会 2021)
Decorin過剰発現がマウス水晶体組織に与える影響
(第125回日本眼科学会総会 2021)

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Education (1)：

Professional career (1)：

Work history (4)：

2011/01 - Kanazawa Medical University
2009/04 - 2010/12 JSPS JSPS fellowship (NIH)
2007/01 - 2010/12 National Institutes of Dental and Craniofacial Research / National Institutes of Health Researcher
2004/04 - Kyoto Sangyo University

Awards (3)：

2018/07 - JunB regulates angiogenesis and neurovascular parallel alignment in mouse embryonic skin.
2018/07 - 第57回日本白内障学会総会・第44回水晶体研究会優秀演題賞
2009/04 - NIH Japan Society for the Promotion of Sciences Fellowship Award

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