Fumi Shima, Yoko Yoshikawa, Yoshiteru Makino, Hirokazu Kubota, Takashi Kawamura, Shigeyuki Matsumoto, Hitomi Yuki, Akira Shibaike, Megumi Okamura, Tomoyo Okada, et al. Small-molecule RAS/RAF Binding Inhibitors Allosterically Disrupt RAF Conformation and Exert Efficacy Against a Broad Spectrum of RAS-driven Cancers. 2024
Hideo Okumura, Naoki Sakai, Hironori Murakami, Nobuhiro Mizuno, Yuki Nakamura, Go Ueno, Takuya Masunaga, Takashi Kawamura, Seiki Baba, Kazuya Hasegawa, et al. In situ crystal data-collection and ligand-screening system at SPring-8. Acta crystallographica. Section F, Structural biology communications. 2022. 78. Pt 6. 241-251
Seiki Baba, Hiroaki Matsuura, Takashi Kawamura, Naoki Sakai, Yuki Nakamura, Yoshiaki Kawano, Nobuhiro Mizuno, Takashi Kumasaka, Masaki Yamamoto, Kunio Hirata. Guidelines for de novo phasing using multiple small-wedge data collection. Journal of Synchrotron Radiation. 2021. 28. 5. 1284-1295
Shigeyuki Matsumoto, Haruka Taniguchi-Tamura, Mitsugu Araki, Takashi Kawamura, Ryo Miyamoto, Chiemi Tsuda, Fumi Shima, Takashi Kumasaka, Yasushi Okuno, Tohru Kataoka. Oncogenic mutations Q61L and Q61H confer active form-like structural features to the inactive state (state 1) conformation of H-Ras protein. Biochemical and Biophysical Research Communications. 2021. 565. 85-90
Kazuya Hasegawa, Seiki Baba, Takashi Kawamura, Masaki Yamamoto, Takashi Kumasaka. Evaluation of the data-collection strategy for room-temperature micro-crystallography studied by serial synchrotron rotation crystallography combined with the humid air and glue-coating method. Acta Crystallographica Section D Structural Biology. 2021. 77. 3. 300-312
Shigeyuki Matsumoto, Haruka Taniguchi-Tamura, Mitsugu Araki, Takashi Kawamura, Ryo Miyamoto, Chiemi Tsuda, Yasushi Okuno, Fumi Shima, Takashi Kumasaka, Tohru Kataoka. Novel Insights into the Structural Perturbation Induced by the Oncogenic Mutations, Q61L and Q61H, in Ras State 1. BIOPHYSICAL JOURNAL. 2020. 118. 3. 42A-42A
Takayuki Nagae, Takashi Kawamura, Leonard Chavas, Ken Niwa, Masashi Hasegawa, Chiaki Kato, Nobuhisa Watanabe. Structure study of IPMDH from piezosensitive and piezophilic Shewanella species. ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES. 2011. 67. C275-C276
Time-resolved structure analysis of restriction endonuclease HindIII
(International Conference of Structural Genomics 2013 - Structural Life Science - 2013)
Education (2):
2003 - 2009 Hokkaido University Graduate School of Science Division of Biological Science
2001 - 2003 Hokkaidou University Graduate School of Science Division of Biological Science
Professional career (1):
博士(理学) (北海道大学)
Work history (5):
2022/04 - 現在 Japan Synchrotron Radiation Research Institute Structural Biology Division Research Scientist
2016/04 - 2022/03 Japan Synchrotron Radiation Research Institute Protein Crystal Analysis Division Research Scientist
2014/08 - 2016/03 Kobe University Graduate School of Medicine academic researcher
2011/04 - 2014/03 Nagoya University Synchrotron Radiation Research Center researcher
2009/04 - 2011/03 Nagoya University Venture Buisiness Laboratory postdoctral fellow
Association Membership(s) (4):
The Japanese Biochemical Society
, Japan Society for Bioscience, Biotechnology, and Agrochemistry
, The Societu of Biotechnology, Japan
, PROTEIN SCIENCE SOCIETY OF JAPAN