Shiraishi Miyako

Affiliation and department：

Research field (2)： Applied biochemistry , Applied microbiology

Research keywords (5)：複製前複合体 , DNA replication , thermophiles , Archaea , DNA repair

Research theme for competitive and other funds (9)：

2024 - 2027 ヒトCdt1がライセンス化において果たすクロマチン構造制御のメカニズムの解明
2022 - 2026 古細菌が持つ独特なヌクレオチド除去修復機構の解明
2024 - 2024 Development of a Robust and Versatile Enhancer for Isothermal Nucleic Acid Amplification
2022 - 2024 RNA binding abilities of typical DNA repair proteins
2020 - 2021 古細菌が持つXPBとXPDの役割の解明

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Papers (11)：

Corina N D'Alessandro-Gabazza, Taro Yasuma, Tetsu Kobayashi, Masaaki Toda, Ahmed M Abdel-Hamid, Hajime Fujimoto, Osamu Hataji, Hiroki Nakahara, Atsuro Takeshita, Kota Nishihama, et al. Inhibition of lung microbiota-derived proapoptotic peptides ameliorates acute exacerbation of pulmonary fibrosis. Nature communications. 2022. 13. 1. 1558-1558
Miyako Shiraishi, Michihi Hidaka, Shigenori Iwai. Endonuclease V from the archaeon Thermococcus kodakarensis is an inosine-specific ribonuclease. Bioscience, biotechnology, and biochemistry. 2021
Miyako Shiraishi, Kento Mizutani, Junpei Yamamoto, Shigenori Iwai. Mutational analysis of Thermococcus kodakarensis endonuclease III reveals the roles of evolutionarily conserved residues. DNA Repair. 2020. 90. 102859
Kei Kunimasa, Yuya Bando, Miyako Shiraishi, Emi Aizawa, Kazumi Nishino, Motohiro Tamiya, Takoko Inoue, Hanako Kuhara, Hayato Kawachi, Kika Kuno, et al. Development CRISPR-Cas12-based rapid EGFR mutation detection kit. JOURNAL OF CLINICAL ONCOLOGY. 2020. 38. 15
Shiraishi M, Iwai S. Molecular Basis of Substrate Recognition of Endonuclease Q from the Euryarchaeon Pyrococcus furiosus. Journal of bacteriology. 2020. 202. 2

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Patents (2)：

Lectures and oral presentations (15)：

古細菌群に保存される真核生物型ヌクレオチド除去修復因子XPBの機能解析
(第46回日本分子生物学会年会 2023)
クリックケミストリーを用いたCRISPR-Cas模倣型タンパク質の開発とイメージングへの応用
(第46回日本分子生物学会年会 2023)
Current understanding of DNA repair mechanisms in archaea
(45th Annual Meeting of the Molecular Biology Society of Japan 2022)
Elucidation of mechanism for chromatin regulation by Cdt1 and Cdt1-interacting chromatin handling factors
(45th Annual Meeting of the Molecular Biology Society of Japan 2022)
アーキア型RPA及びRadAのRNAに対する機能解析
(極限環境生物学会2021年度(第22回)年会 2021)

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Education (3)：

2014 - 2017 Kyushu University Ph.D. in Agricultural Science, Graduate School of Bioresource and Bioenvironmental Science
2012 - 2014 Kyushu University M.A. of Agricultural Science, Graduate School of Bioresource and Bioenvironmental Science
2008 - 2012 Kyushu University B.A. of Agricultural Science, School of Agriculture and Bioenvironmental Science

Professional career (1)：

Work history (5)：

2022/05 - 現在 Kyushu University Graduate School of Pharmaceutical Sciences Assistant professor
2018/09 - 2022/05 Osaka University Assistant Professor
2017/04 - 2017/08 九州大学大学院農学研究院学術特定研究者
2014/04 - 2017/03 日本学術振興会特別研究員 DC1
2014/05 - 2016/12 University of Illinois at Urbana-Champaign Visiting Scholar

Committee career (1)：

Awards (5)：

2017/03 - 平成28年度生物資源環境科学府賞
2017/03 - 九州大学学生表彰受賞
2017/01 - 平成28年度日本農芸化学会西日本支部奨励賞(学生)
2016/09 - The International Society for Extremophiles The International Society for Extremophiles Poster Award A novel DNA repair pathway for damaged bases in Thermococcles
2013/06 - Protein Science Society of Japan Poster Awards for Young Scientists Identification of a novel repair endonuclease from the hyperthermophilic archaeon Pyrococcus furiosus

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