Matsumura Tomohiro

マツムラトモヒロ | Matsumura Tomohiro

Affiliation and department：

Research field (1)： Medical biochemistry

Research theme for competitive and other funds (10)：

2014 - 2018 Development of a novel treatment for inner ear deafness -inhibition of the expression of Cochlin with RNAi-
2008 - 2010 Phasogenesis study of XOR mutant knock-in mouse.
2004 - 2007 Determination of fine structure of the molybdo-enzyme and mechanism of hydroxylation and protein vibration.
2004 - 2006 モリブデン酵素の活性化を調節する新規タンパク質の反応機構
2000 - 2004 活性酸素種による遺伝子発現誘導の分子基盤

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Papers (31)：

Akira Sasaki, Tetsuo Ikezono, Han Matsuda, Ryuichiro Araki, Tomohiro Matsumura, Shiho Saitoh, Koichiro Wasano, Atsushi Matsubara. Prevalence of perilymphatic fistula in patients with sudden-onset sensorineural hearing loss as diagnosed by Cochlin-tomoprotein (CTP) biomarker detection: its association with age, hearing severity, and treatment outcomes. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 2024. 281. 5. 2373-2381
Seiko Noda, Asako Yamada, Yasunobu Asawa, Hiroyuki Nakamura, Tomohiro Matsumura, Hideo Orimo, Masae Goseki-Sone. Characterization and Structure of Alternatively Spliced Transcript Variant of Human Intestinal Alkaline Phosphatase (ALPI) Gene. Journal of nutritional science and vitaminology. 2022. 68. 4. 284-293
Han Matsuda, Yasuhiko Tanzawa, Tatsuro Sekine, Tomohiro Matsumura, Shiho Saito, Susumu Shindo, Shin-Ichi Usami, Yasuhiro Kase, Akinori Itoh, Tetsuo Ikezono. Congenital Membranous Stapes Footplate Producing Episodic Pressure-Induced Perilymphatic Fistula Symptoms. Frontiers in neurology. 2020. 11. 585747-585747
Teruo Kusano, Driss Ehirchiou, Tomohiro Matsumura, Veronique Chobaz, Sonia Nasi, Mariela Castelblanco, Alexander So, Christine Lavanchy, Hans Acha-Orbea, Takeshi Nishino, et al. Targeted knock-in mice expressing the oxidase-fixed form of xanthine oxidoreductase favor tumor growth. Nature communications. 2019. 10. 1. 4904-4904
Suma Uday, Tomohiro Matsumura, Vrinda Saraff, Shiho Saito, Hideo Orimo, Wolfgang Högler. Tissue non-specific alkaline phosphatase activity and mineralization capacity of bi-allelic mutations from severe perinatal and asymptomatic hypophosphatasia phenotypes: Results from an in vitro mutagenesis model. Bone. 2019. 127. 9-16

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MISC (50)：

松村智裕. 基礎的データから考えるCTP検査測定. 日本耳科学会総会・学術講演会抄録集. 2023. 33回. 74-74
田中里沙, 古賀太郎, 草野輝男, 岩崎俊雄, 松村智裕. 固定化ヒト・アルカリホスファターゼは食品成分でリフォールディングする. 日本生化学会大会プログラム・講演要旨集. 2023. 96回. [2P-655]
松村智裕, 齋藤志ほ, 池園哲郎. 外リンパ瘻疾患のバイオマーカーCTPのラットでの検討. 日本生化学会大会プログラム・講演要旨集. 2022. 95回. 2P-317
齋藤志ほ, 松村智裕, 草野輝男, 折茂英生. 変性アルカリホスファターゼの牛乳による活性回復. 日本生化学会大会プログラム・講演要旨集. 2021. 94回. [P-290]
酒井涼, 松村智裕, 岩崎俊雄, 草野輝男, 折茂英生. 疾患由来アルカリホスファターゼ変異酵素解析に向けた組換え酵素再構成系の検討. 日本医科大学医学会雑誌. 2021. 17. 4. 249-249

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Professional career (1)：

博士(理学) (大阪大学)

Work history (2)：

2019/04 - 現在 Nippon Medical School
1997/04 - 2019/03 Nippon Medical School

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