Rchr
J-GLOBAL ID:201801004449082439
Update date: Apr. 02, 2025
OIKAWA Tsunekazu
オイカワ ツネカズ | OIKAWA Tsunekazu
Affiliation and department:
Research field (2):
Gastroenterology
, Cell biology
Research keywords (5):
バイオマーカー
, 肝癌
, 幹細胞
, 肝再生
, 肝疾患
Research theme for competitive and other funds (8):
- 2023 - 2025 新規タンパク質分泌機構CUPSを標的としたがん治療薬の研究開発
- 2022 - 2025 肝癌特異的な細胞外分泌蛋白を用いた新規早期診断法確立とその実用化に向けた検証研究
- 2021 - 2024 早期肝がんに対するPKCδ を用いた新規高感度診断法の開発
- 2019 - 2022 Gene therapy development in liver cancer
- 2016 - 2019 The role of DYRK2 in primary liver cancers
- 2015 - 2016 肝癌の起源と癌幹細胞の制御機構及び新規治療法の解明
- 2010 - 2011 肝癌幹細胞における発癌、進展制御メカニズムの解明
- 2008 - 2009 Analyses of cell fate determination in fetal hepatoblast
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Papers (65):
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Kaori Koyano, Masanori Atsukawa, Akihito Tsubota, Chisa Kondo, Takao Miwa, Tadashi Namisaki, Atsushi Hiraoka, Hidenori Toyoda, Toshifumi Tada, Yuji Kobayashi, et al. Association Between Laboratory Values and Covert Hepatic Encephalopathy in Patients with Liver Cirrhosis: A Multicenter, Retrospective Study. Journal of Clinical Medicine. 2025. 14. 6. 1858-1858
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Kaoru Ueda, Tsunekazu Oikawa, Kohji Yamada, Akihito Tsubota, Chisato Saeki, Kuniko Katagiri, Naoko Tago, Ayano Matsumoto, Hayato Mikuni, Masashi Ishikawa, et al. Serum PKCδ is a useful biomarker to distinguish hepatocellular carcinoma from other gastrointestinal cancers. Biochemical and Biophysical Research Communications. 2025. 751. 151431-151431
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Takashi Niwa, Chisato Saeki, Mitsuru Saito, Tsunekazu Oikawa, Hiroshi Kamioka, Tomoya Kanai, Kaoru Ueda, Masanori Nakano, Yuichi Torisu, Masayuki Saruta, et al. Impact of frailty and prevalent fractures on the long-term prognosis of patients with cirrhosis: a retrospective study. Scientific Reports. 2025. 15. 1
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Yuki Tamura, Chisato Saeki, Tomoya Kanai, Sachie Kiryu, Masanori Nakano, Tsunekazu Oikawa, Yuichi Torisu, Masayuki Saruta, Akihito Tsubota. Comparison of the ability between dual-energy X-ray absorptiometry and bioelectrical impedance analysis for diagnosing low skeletal muscle mass and sarcopenia in patients with chronic liver disease. Journal of Gastroenterology and Hepatology. 2024. 40. 1. 274-281
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Taeang Arai, Masanori Atsukawa, Akihito Tsubota, Tsunekazu Oikawa, Toshifumi Tada, Kentaro Matsuura, Toru Ishikawa, Hiroshi Abe, Keizo Kato, Asahiro Morishita, et al. Beneficial effect of oral semaglutide for type 2 diabetes mellitus in patients with metabolic dysfunction-associated steatotic liver disease: A prospective, multicentre, observational study. Diabetes, obesity & metabolism. 2024. 26. 11. 4958-4965
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MISC (9):
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春木 孝一郎, 恩田 真二, 古川 賢英, 安田 淳吾, 恒松 雅, 柳垣 充, 谷合 智彦, 及川 恒一, 猿田 雅之, 池上 徹. 予後から定義するBorderline resectable肝細胞癌と集学的治療戦略. 日本消化器外科学会総会. 2023. 78回. O43-4
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及川恒一, 山田幸司, 坪田昭人, 佐伯千里, 上田薫, 神岡洋, 春木孝一郎, 池上徹, 吉田清嗣, 猿田雅之. 早期診断に有用な肝細胞癌特異的バイオマーカー血清PKCδ. 肝細胞研究会プログラム・抄録集. 2023. 30th
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横山 寛, 政木 隆博, 井上 育代, 中村 まり子, 目崎 喜弘, 佐伯 千里, 及川 恒一, 猿田 雅之, 鷹橋 浩幸, 池上 雅博, et al. 慢性肝疾患患者におけるTGF-β活性化の組織学的・血液生化学的評価と臨床的意義. 東京慈恵会医科大学雑誌. 2019. 134. 6. 110-110
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Shinya Fukunishi, Keisuke Yokohama, Akira Asai, Kazuhide Higuchi, Toshihide Shima, Takeshi Okanoue, Takuya Genda, Yoshio Aizawa, Tsunekazu Oikawa, Yoshihiro Matsumoto, et al. EFFICACY AND SAFETY OF GLECAPREVIR/PIBRENTASVIR IN PATIENTS WITH SEVERE RENAL IMPAIRMENT IN JAPAN: A PROSPECTIVE, MULTICENTER STUDY (KTK 49 LIVER STUDY GROUP). HEPATOLOGY. 2019. 70. 960A-961A
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Tsunekazu Oikawa, Akihide Kamiya, Mikio Zeniya, Hirokazu Nishino, Hiromitsu Nakauchi, Hisao Tajiri. SALL4, A STEM CELL FACTOR, CONTRIBUTES TO THE TUMOR GROWTH IN HEPATOCELLULAR CARCINOMA. HEPATOLOGY. 2011. 54. 448A-448A
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Patents (1):
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Human Fibrolamellar Hepatocellular Carcinomas (hFL-HCCs)
Books (2):
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幹細胞マーカーSALL4における肝癌治療法の可能性
肝胆膵 2014
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Stem Cell Populations Giving Rise to Liver, Biliary Tree and Pancreas.
A book chapter in Stem cells Handbook, 2nd Edition. Stewart Sell editor, Springer Science+Business Media, New York, NY. 2013
Professional career (1):
- M.D., Ph.D. (Jikei University School of Medicine)
Work history (5):
- 2023/11 - 現在 The Jikei University School of Medicine Department of Internal Medicine, Division of Gastroenterology and Hepatology Associate professor
- 2017/04 - 2023/10 The Jikei University School of Medicine Division of Gastroenterology and Hepatology, Department of Internal Medicine, Assistant professor
- 2015/04 - 2017/03 The Jikei University School of Medicine Division of Gastroenterology and Hepatology, Department of Internal Medicine, Assistant professor
- 2011/09 - 2015/03 University of North Carolina School of Medicine at Chapel Hill Department of Cell Biology and Physiology, Postdoctral Research Associate
- 2007/06 - 2008/03 The Institute of Medical Science, University of Tokyo Division of Stem Cell Therapy, Center for Stem Cell and Regenerative Medicine, Research Fellow
Awards (6):
- 2014 - 公益財団法人上原記念生命科学財団 上原海外留学助成金リサーチフェローシップ
- 2013/11 - 64th Annual Meeting of the American Association for the Study of Liver Diseases. Professor Margit Hamosh Memorial Travel Award.
- 2013/11 - 64th Annual Meeting of the American Association for the Study of Liver Diseases. Presidential Poster of Distinction.
- 2013/10 - 日本肝臓学会 冠アワード 第4回Bristol Myers Award
- 2013/05 - University of North Carolina Lineberger Annual Scientific Retreat. Award Second Prize for Best Posters.
- 2009/09 - 慈恵医師会研究奨励賞
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