Komatsu Tomohiro

コマツトモヒロ | Komatsu Tomohiro

Affiliation and department：

Research field (4)： Metabolism and endocrinology , Cardiology , Sports science , Pharmacology

Research keywords (4)：脂質代謝 , HDL代謝 , 分子骨格筋学 , 肺高血圧症

Research theme for competitive and other funds (5)：

2024 - 2029 Investigation of the muscle differentiation-promoting effects by high-density lipoprotein (HDL) and mechanisms of the skeletal muscle HDL production system
2023 - 2026 Elucidation of the mechanism of skeletal muscle failure caused by artificial sweeteners and dietary type, and verification of the effects of exercise
2023 - 2026 脂質代謝因子アポリポ蛋白C2を介した骨格筋発現制御メカニズムの解明
2020 - 2024 Physiological roles and mechanisms of a novel high density lipoprotein (HDL) production system in skeletal muscle.
2020 - 2023 運動による新規中性脂肪低下メカニズムの解明~骨格筋アポ蛋白C2システムを中心に~

Papers (39)：

Masahiro Kuwahara, Tomo Kita, Takayuki Nemoto, Yasuharu Shinoda, Tomohiro Komatsu, Satomi Kita, Takahiro Iwamoto. A combination study of benzyloxyphenyl NCX inhibitor and its insensitive Slc8a1 mutation knock-in mouse reveals NCX1-specific physiological functions. Biochemical and biophysical research communications. 2025. 785. 152699-152699
Tomohiro Komatsu, Satomi Abe, Masayuki Kuroda, Yasuhiro Endo, Kei Sasaki, Takafumi Nishida, Manami Teramoto, Junko Arakawa, Koji Kuwata, Toshihiko Imakiire, et al. Short-Term Treatment for Immune-Mediated Acquired Lecithin-Cholesterol Acyltransferase Deficiency Restores the High-Density Lipoprotein Function: A Case Report. Journal of atherosclerosis and thrombosis. 2025
Tomohiro Komatsu, Yoshinari Uehara. HDL Cholesterol Concentration may Become One of the Predictors for Future Renal Dysfunction in JAPAN. Journal of atherosclerosis and thrombosis. 2025. 32. 4. 405-406
Kei Sasaki, Hayato Tada, Tomohiro Komatsu, Hisato Terada, Yasuhiro Endo, Katsunori Ikewaki, Yoshinari Uehara. A New Case of Abetalipoproteinemia Caused by Novel Compound Heterozygote Mutations in the MTTP Gene without Fat or Vitamin Malabsorption. Journal of Atherosclerosis and Thrombosis. 2024. 31. 11. 1634-1640
Takafumi Nishida, Makoto Ayaori, Junko Arakawa, Yumiko Suenaga, Kazusa Shiotani, Harumi Uto-Kondo, Tomohiro Komatsu, Kazuhiro Nakaya, Yasuhiro Endo, Makoto Sasaki, et al. Liver-specific Lxr inhibition represses reverse cholesterol transport in cholesterol-fed mice. Atherosclerosis. 2024. 117578

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MISC (14)：

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Books (5)：

日本臨床第78巻増刊号2 高血圧学(下)
日本臨床社 2020
欧州心臓病学会(ESC)心血管薬物療法ハンドブック日本語翻訳版
OXFORD UNIVERSITY PRESS 2020
疾病の成り立ち(新スタンダード栄養・食物シリーズ4)
東京化学同人 2015 ISBN:9784807916641
脂質異常症診療ガイド Q&A
南山堂 2014 ISBN:9784525234010
成功に導くPCI治療戦略
南江堂 2011 ISBN:9784524263134

Lectures and oral presentations (41)：

骨格筋を介したHDL模倣ペプチドによるマウス耐糖能の改善効果
(第54回日本心脈管作動物質学会 2025)
Short-term treatment for acquired HDL deficiency restores HDL function.
(20th INTERNATIONAL SYMPOSIUM ON ATHEROSCLEROSIS, Muscat (Oman) 2024)
脂質・脂溶性ビタミン吸収障害のないMTTP複合ヘテロ接合体の1例
(日本動脈硬化学会総会プログラム・抄録集 2024)
IgG4 関連 LCAT 自己抗体による後天性 LCAT 欠損症の一例
(第55回日本動脈硬化学会総会・学術集会シンポジウム7 2023)
High-density lipoprotein mimetics promote mitochondrial function in mouse skeletal muscle.
(6th Asia-Pacific CardioMetabolic Syndrome Congress 2023, Seoul, Korea 2023)

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Professional career (1)：

博士(医学) (防衛庁防衛医科大学校)

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