J-GLOBAL ID:201801004776532138   Update date: Apr. 05, 2024

Komatsu Tomohiro

コマツ トモヒロ | Komatsu Tomohiro
Affiliation and department:
Research field  (4): Metabolism and endocrinology ,  Cardiology ,  Sports science ,  Pharmacology
Research keywords  (4): 脂質代謝 ,  HDL代謝 ,  分子骨格筋学 ,  肺高血圧症
Research theme for competitive and other funds  (2):
  • 2020 - 2024 Physiological roles and mechanisms of a novel high density lipoprotein (HDL) production system in skeletal muscle.
  • 2020 - 2023 運動による新規中性脂肪低下メカニズムの解明~骨格筋アポ蛋白C2システムを中心に~
Papers (34):
  • Yoshinari Uehara, Tomohiro Komatsu, Kei Sasaki, Satomi Abe, Shihoko Nakashima, Taiki Yamamoto, Ji-Eun Kim, Kyung-Hyun Cho. Cuban policosanol improves high-density lipoprotein cholesterol efflux capacity in healthy Japanese subjects. Frontiers in Nutrition. 2024. 10
  • Tomohiro Komatsu, Yuka Katsurada, Kazuya Miyashita, Satomi Abe, Takafumi Nishida, Yasuhiro Endo, Manami Teramoto, Kei Sasaki, Junko Arakawa, Makoto Sasaki, et al. Two Cases of Acquired High-Density Lipoprotein Deficiency with Immunoglobulin G4-Related Lecithin-Cholesterol Acyltransferase Autoantibody. Journal of Atherosclerosis and Thrombosis. 2023
  • Kyung-Hyun Cho, Ji-Eun Kim, Tomohiro Komatsu, Yoshinari Uehara. Protection of Liver Functions and Improvement of Kidney Functions by Twelve Weeks Consumption of Cuban Policosanol (Raydel®) with a Decrease of Glycated Hemoglobin and Blood Pressure from a Randomized, Placebo-Controlled, and Double-Blinded Study with Healthy and Middle-Aged Japanese Participants. Life. 2023. 13. 6. 1319-1319
  • Yukiya Tanoue, Shihoko Nakashima, Tomohiro Komatsu, Miki Kosugi, Saki Kawakami, Shotaro Kawakami, Ryoma Michishita, Yasuki Higaki, Yoshinari Uehara. The Validity of Ultra-Short-Term Heart Rate Variability during Cycling Exercise. Sensors. 2023. 23. 6. 3325-3325
  • Kyung-Hyun Cho, Hyo-Seon Nam, Seung-Hee Baek, Dae-Jin Kang, Hyejee Na, Tomohiro Komatsu, Yoshinari Uehara. Beneficial Effect of Cuban Policosanol on Blood Pressure and Serum Lipoproteins Accompanied with Lowered Glycated Hemoglobin and Enhanced High-Density Lipoprotein Functionalities in a Randomized, Placebo-Controlled, and Double-Blinded Trial with Healthy Japanese. International Journal of Molecular Sciences. 2023. 24. 6. 5185-5185
MISC (14):
Books (5):
  • 日本臨床第78巻増刊号2 高血圧学(下)
    日本臨床社 2020
  • 欧州心臓病学会(ESC)心血管薬物療法ハンドブック 日本語翻訳版
  • 疾病の成り立ち(新スタンダード栄養・食物シリーズ4)
    東京化学同人 2015 ISBN:9784807916641
  • 脂質異常症 診療ガイド Q&A
    南山堂 2014 ISBN:9784525234010
  • 成功に導くPCI治療戦略
    南江堂 2011 ISBN:9784524263134
Lectures and oral presentations  (38):
  • High-density lipoprotein mimetics promote mitochondrial function in mouse skeletal muscle.
    (6th Asia-Pacific CardioMetabolic Syndrome Congress 2023, Seoul, Korea 2023)
  • 血管平滑筋特異的NCX2遺伝子改変マウスを用いた肺高血圧症モデル実験
    (第75回 日本薬理学会西南部会 2022)
  • HDL mimetics promotes mitochondrial function in mouse myoblast cells.
    (第95回 日本薬理学会年会 2022)
  • 突然死を引き起こす心筋特異的NCX1欠損マウスの心筋細胞Ca2+シグナル異常
    (第74回日本薬理学会西南部会 2021)
  • 糖尿病治療薬シタグリプチンは、ヒト単球由来マクロファージのcholesterol effluxを促進する
    (第6回日本血管不全学会 学術集会・総会 2021)
Professional career (1):
  • 博士(医学) (防衛庁 防衛医科大学校)
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