Rchr
J-GLOBAL ID：201801004917277889   Update date: Nov. 22, 2024

Suzuki Ikuo K

Suzuki Ikuo | Suzuki Ikuo K
Affiliation and department：
The University of Tokyo Graduate School of Science Department of Biological Sciences

About The University of Tokyo Graduate School of Science Department of Biological Sciences


Job title： Associate Professor
Homepage URL  (1)： http://www.bs.s.u-tokyo.ac.jp/
Research field  (4)： Genomics ,  Neuroscience - general ,  Evolutionary biology ,  Developmental biology
Research keywords  (12)： Evo-Devo ,  gene duplication ,  pluripotent stem cell ,  human specific gene ,  neurogenesis ,  NOTCH2NL ,  NOTCH ,  cell lineage ,  evolution ,  development ,  neural stem cell ,  cerebral cortex
Research theme for competitive and other funds  (10)：
  • 2023 - 2027 Human biologies through the lens of human-specific genes
  • 2023 - 2026 Study of the genetic association between recently duplicated genes and brain diseases
  • 2022 - 2025 The balancing mechanism of signal transduction driving human brain evolution
  • 2022 - 2025 Searching for genetic programs driving human brain evolution
  • 2019 - 2024 Deciphering molecular developmental mechanisms driving human cerebral cortical evolution
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Papers (20)：
  • Satoshi Inagaki, Yuya Morimoto, Ikuo K. Suzuki, Kazuo Emoto, Shoji Takeuchi. Co-culture system of human skin equivalents with mouse neural spheroids. Journal of Bioscience and Bioengineering. 2023
  • Louis-Jan Pilaz, Jing Liu, Kaumudi Joshi, Yuji Tsunekawa, Camila M. Musso, Brooke R. D’Arcy, Ikuo K. Suzuki, Fernando C. Alsina, Pratiksha KC, Sahil Sethi, et al. Subcellular mRNA localization and local translation of Arhgap11a in radial glial progenitors regulates cortical development. Neuron. 2023. 111. 6. 839-856.e5
  • Roxane Van Heurck, Jerome Bonnefont, Marta Wojno, Ikuo K. Suzuki, Fausto D. Velez-Bravo, Emir Erkol, Dan Truc Nguyen, Adele Herpoel, Angeline Bilheu, Sofie Beckers, et al. CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors. Neuron. 2023. 111. 1. 1-16
  • Ryota Nakahama, Aika Saito, Sensho Nobe, Kazuya Togashi, Ikuo K. Suzuki, Akira Uematsu, Kazuo Emoto. The tyrosine capsid mutations on retrograde adeno-associated virus accelerates gene transduction efficiency. Molecular Brain. 2022. 15. 1. 70-70
  • Ikuo K. Suzuki. Evolutionary innovations of human cerebral cortex viewed through the lens of high-throughput sequencing. Developmental Neurobiology. 2022. 82. 6. 476-494
ｍore...
MISC (5)：
  • 鈴木郁夫, 天野麟太郎, 榎本和夫. 大規模データから明らかになる、大脳皮質におけるヒト独自の細胞構成とその発生メカニズム. 実験医学増刊. 2023. 42. 76-83
  • Ikuo K. Suzuki. Human-specific gene NOTCH2NL drives brain evolution, diversifi cation, and various diseases. 2023. 55. 3. 32-35
  • 曽根 淳, 三橋 里美, 藤田 京志, 森 恵子, 小池 春樹, 高嶋 博, 杉山 博, 河野 豊, 瀧山 嘉久, 前田 健吾, et al. Neuronal intranuclear inclusion disease(神経核内封入体病)の原因遺伝子同定. Dementia Japan. 2019. 33. 4. 513-513
  • 鈴木 郁夫, Pierre Vanderhaeghen. ヒトに固有なNOTCH2NLB遺伝子はNotchシグナルの制御を介して大脳皮質のニューロンを増加させる. ライフサイエンス 新着論文レビュー
  • 鈴木郁夫, 平田たつみ. 大脳新皮質における神経新生プログラムの哺乳類と鳥類との進化的な保存性. ライフサイエンス 新着論文レビュー
Lectures and oral presentations  (54)：
  • Recent expansion and evolutionary selection of human-specific NOTCH2NLB allele enhancing cortical neurogenesis
    (25th Biennial Conference of the International Society for Developmental Neuroscience (ISDN) 2024)
  • Recent expansion and evolutionary selection of human-specific NOTCH2NLB allele enhancing cortical neurogenesis
    (EMBO | EMBL symposium: Reconstructing the human past: using ancient and modern genomics 2024)
  • An evolutionary new allele of human-specific gene NOTCH2NLB that enhances cortical neurogenesis is positively selected in the modern human population
    (2024)
  • An evolutionary novel allele of human-specific gene NOTCH2NLB is positively selected and enhances cortical neurogenesis
    (The 13th Annual Meeting of Japan Society of Marmoset Research 2024)
  • Evolutionary dynamics of human-specific NOTCH2NL during the expansion of modern human population
    (The 46th annual meeting of the Molecular Biology Society of Japan 2023)
ｍore...
Education (2)：
  • 2005 - 2010 The Graduate University for Advanced Studies School of Life Science Department of Genetics
  • 2001 - 2005 Kyoto University
Professional career (1)：
  • PhD (The graduate university of advanced studies, Japan)
Work history (6)：
  • 2019/01 - 現在 The University of Tokyo Department of Biological Sciences, The School of Science Associate professor
  • 2019/01 - 2019/06 VIB KU Leuven, Center for Brain & Disease Research (CBD) Pierre Vanderhaeghen group Visiting Researcher
  • 2018/10 - 2018/12 The University of Tokyo Department of Biological Sciences, The School of Science Visiting scientist
  • 2018/03 - 2018/12 VIB KU Leuven, Center for Brain & Disease Research (CBD) Pierre Vanderhaeghen group Postdoctoral Researcher
  • 2012/02 - 2018/02 University of Brussels (ULB) IRIBHM Pierre Vanderhaeghen group Postdoctoral Researcher
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Awards (5)：
  • 2019/06 - Japan Neuroscience Society Japan Neuroscience Society Young Investigator Award
  • 2019/05 - The Molecular Biology Society of Japan Tomizawa Jun-ichi & Keiko Fund of Molecular Biology Society of Japan for Young Scientist (Tomizawa Fund Award), Japan
  • 2019/01 - 東京大学 2018年度東京大学卓越研究員
  • 2014/10 - F.R.S.-FNRS (le Fonds de la Recherche Scientifique, Belgium) Postdoctoral longterm fellowship (CR)
  • 2012/07 - European Molecular Biology Organization (EMBO) Long-Term Fellowships
Association Membership(s) (4)：
THE ZOOLOGICAL SOCIETY OF JAPAN ,  JAPANESE SOCIETY OF DEVELOPMENTAL BIOLOGISTS ,  THE JAPAN NEUROSCIENCE SOCIETY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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