Furukawa Ayako

フルカワアヤコ | Furukawa Ayako

Affiliation and department：

Research field (1)： Pharmacology

Research theme for competitive and other funds (13)：

2022 - 2025 損傷後視神経における神経-グリア連関による新規再生メカニズムの解析
2019 - 2022 Elucidation of the mechanism in Alzheimer's disease through advanced glycation end products by glyceraldehyde
2019 - 2022 Elucidation of molecular mechanisms of neurodegeneration caused by dysfunctional senescent astrocytes
2019 - 2022 Development of a next-generation platinum-based drug with a markedly high and long-lasting antitumor efficacy
2016 - 2019 HSP70 targeting therapy for retinitis pigmentosa

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Papers (47)：

Hayahide Ooi, Ayako Furukawa, Masayoshi Takeuchi, Yoshiki Koriyama. Toxic Advanced Glycation End-Products Inhibit Axonal Elongation Mediated by β-Tubulin Aggregation in Mice Optic Nerves. International Journal of Molecular Sciences. 2024. 25. 13. 7409-7409
Hayahide Ooi, Ryuto Nasu, Ayako Furukawa, Masayoshi Takeuchi, Yoshiki Koriyama. Pyridoxamine and Aminoguanidine Attenuate the Abnormal Aggregation of β-Tubulin and Suppression of Neurite Outgrowth by Glyceraldehyde-Derived Toxic Advanced Glycation End-Products. Frontiers in pharmacology. 2022. 13. 921611-921611
Masayoshi Takeuchi, Akiko Sakasai-Sakai, Takanobu Takata, Jun-Ichi Takino, Yoshiki Koriyama, Chigusa Kikuchi, Ayako Furukawa, Kentaro Nagamine, Takamitsu Hori, Tamihide Matsunaga. Intracellular Toxic AGEs (TAGE) Triggers Numerous Types of Cell Damage. Biomolecules. 2021. 11. 3
那須隆斗, 古川絢子, 竹内正義, 郡山恵樹. 糖尿病由来アルツハイマー病発症における毒性終末糖化産物(TAGE)関与の可能性. 日本薬学会年会要旨集. 2021. 141年会. 28P02-236
竹内正義, 逆井亜紀子[坂井], 高田尊信, 瀧野純一, 郡山恵樹, 菊池千草, 古川絢子, 長嶺憲太郎, 堀隆光, 松永民秀. 細胞内Toxic AGEs(TAGE)の生成・蓄積は各種細胞障害のトリガーとなる. 日本薬学会年会要旨集. 2021. 141年会. 28P02-235

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MISC (25)：

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