Research field (2):
Pharmacology
, Neuroscience - general
Research keywords (1):
electrophysiology, behavioral study, pain, itch
Research theme for competitive and other funds (3):
2023 - 2025 The analysis of the analgesic effects of novel glycine receptor positive allosteric modulators (PAMs) and their synaptic mechanisms
2022 - 2025 Pharmacological analysis of antipruritic effects of gabapentinoid
2019 - 2022 The synaptic analgesic mechanisms of KCNQ (Kv7) K+ channel opener in the spinal dorsal horn.
Papers (7):
Takashi Iwai, Rei Mishima, Shigeto Hirayama, Honoka Nakajima, Misa Oyama, Shun Watanabe, Hideaki Fujii, Mitsuo Tanabe. SYK-623, a δ Opioid Receptor Inverse Agonist, Mitigates Chronic Stress-Induced Behavioral Abnormalities and Disrupted Neurogenesis. Journal of Clinical Medicine. 2024. 13. 2. 608-608
Motoki Morita, Shun Watanabe, Natsumi Nomura, Kanako Takano-Matsuzaki, Misa Oyama, Takashi Iwai, Mitsuo Tanabe. Sulfatide-selectin signaling in the spinal cord induces mechanical allodynia. Journal of neurochemistry. 2022
Misa Oyama, Shun Watanabe, Takashi Iwai, Mitsuo Tanabe. Distinct synaptic mechanisms underlying the analgesic effects of γ-aminobutyric acid transporter subtypes 1 and 3 inhibitors in the spinal dorsal horn. Pain. 2022. 163. 2. 334-349
Misa Oyama, Shun Watanabe, Takashi Iwai, Mitsuo Tanabe. Mirogabalin activates the descending noradrenergic system by binding to the α2δ-1 subunit of voltage-gated Ca2+ channels to generate analgesic effects. Journal of pharmacological sciences. 2021. 146. 1. 33-39
2015 - 2017 Kitasato Univ. School of Pharmaceutical Sciences
2009 - 2015 Kitasato Univ. School of Pharmacy Pharmaceutical Scieces
Work history (2):
2023/04 - 現在 University of Zurich Institute of Pharmacology and Toxicology Postdoctoral fellow
2017/04 - 現在 School pf Pharmacy, Kitasato University Laboratory of Pharmacology Assistant Professor
Awards (1):
2022/03 - Young Investigator's Award (YIA) Behavioral and electrophysiological analysis of the analgesic and antipruritic effects of the KCNQ (Kv7) K+ channel opener retigabine.
Association Membership(s) (4):
JAPANESE ASSOCIATION FOR THE STUDY OF PAIN
, THE JAPAN NEUROSCIENCE SOCIETY
, THE JAPANESE PHARMACOLOGICAL SOCIETY
, THE PHARMACEUTICAL SOCIETY OF JAPAN