Yukawa Masashi

ユカワマサシ | Yukawa Masashi

Affiliation and department：
Job title： Assistant Professor

Research field (1)： Applied biochemistry

Research theme for competitive and other funds (9)：

2023 - 2026 Exploring the molecular mechanism of actin-dependent mitotic nuclear positioning
2023 - 2025 酵母を利用した抗がん活性を有する天然物由来新規キネシン阻害剤の探索
2019 - 2022 Elucidation of molecular mechanisms regulating bipolar spindle assembly and its application for next-generation drug discovery
2016 - 2021 Exploring spatiotemporal regulatory mechanisms of proper mitotic spindle assembly mediated by novel evolutionarily conserved pathways
2016 - 2019 Single-molecule visualisation of kinetochore-microtubule interface using the in vitro reconstitution system

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Papers (41)：

Afdilla Fara Difka, Hwang Woosang, Yukawa Masashi. An "In Schizo" Evaluation System to Screen for Human Kinesin-5 Inhibitors. Methods Mol Biol. 2024. 2862. 333-351
Toda, Takashi, Kitamura, Kenji, Kume, Kazunori, Yukawa, Masashi, Koyano, Takayuki, Ueno, Masaru. The joy of the 11th International Fission Yeast Meeting in Hiroshima (POMBE2023 Hiroshima) after a long wait due to the COVID-19 pandemic. GENES TO CELLS. 2023. 28. 9. 646-652
Woosang Hwang, Takashi Toda and Masashi Yukawa. Complementation of fission yeast kinesin-5/Cut7 with human Eg5 provides a versatile platform for screening of anticancer compounds. Bioscience, Biotechnology, and Biochemistry. 2022. 86. 2. 254-259
Masashi Yukawa, Mitsuki Ohishi, Yusuke Yamada and Takashi Toda. The putative RNA-binding protein Dri1 promotes the loading of kinesin-14/Klp2 to the mitotic spindle and is sequestered into heat-induced protein aggregates in fission yeast. International Journal of Molecular Sciences. 2021. 22. 9. 4795
Shintaro Akabane 1 2 , Naohide Oue 1 , Yohei Sekino 3 , Ryuichi Asai 4 , Pham Quoc Thang 1 , Daiki Taniyama 1 , Kazuhiro Sentani 1 , Masashi Yukawa 5 , Takashi Toda 5 , Ken-Ichi Kimura 6 , Hiroyuki Egi 2 , Wataru Shimizu 2 , Hideki Ohdan 2 , Wataru Yasui 1. KIFC1 regulates ZWINT to promote tumor progression and spheroid formation in colorectal cancer. Pathology International. 2021. 71. 7. 441-452

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Books (7)：

A novel pathway involved in mitotic nuclear positioning in fission yeast
Journal of Japanese Biochemical Society 2023
もう一つの広島サミット〜第11回分裂酵母国際学会
羊土社 2023 ISBN:9784758125710
熱ショックシャペロンによるMAPキナーゼ経路の二面的制御
羊土社 2021 ISBN:9784758125413
タンパク質脱リン酸化酵素の“えこ贔屓”:2A型フォスファターゼPP2A-B55はセリンよりスレオニンがお好き
2018 ISBN:9784758125048
今日の話題ヒストン脱アセチル化酵素を介した転写タイミングの調節--細胞増殖・発生・分化の過程での遺伝子発現制御の一端が明らかに
2007

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Lectures and oral presentations (80)：

Exploration of novel kinesin-targeted anticancer drugs using yeast-based platform
(RIKEN BDR Symposium 2025 Towards Redesigning Lifecycles 2025)
分裂酵母を利用したヒトM期キネシンモーター阻害活性物質の探索
(日本農芸化学会中四国支部第70回講演会 2025)
分裂期におけるアクチン繊維に依存した細胞核配置の分子制御機構
(日本農芸化学会中四国支部第70回講演会 2025)
An "in schizo" evaluation system to screen for human kinesin-5 and kinesin-12 inhibitors
(2024)
分裂酵母を利用したヒトM期キネシンモーター阻害活性物質の探索
(第41回イーストワークショップ 2024)

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Association Membership(s) (3)：

Yeast Genetics Society of Japan , The Molecular Biology Society of Japan (MBSJ) , Japan Society for Bioscience, Biotechnology, and Agrochemistry (JSBBA)

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