Rchr
J-GLOBAL ID：201801005187032318
Update date: Oct. 28, 2024
Shimada Issei
シマダ イッセイ | Shimada Issei
Affiliation and department：
Job title：
Junior Associate Professor
Research field (4)：
Cell biology
, Developmental biology
, Neuroanatomy and physiology
, Anatomy
Research keywords (14)：
脳オルガノイド
, Neural development
, Transcription Factor
, Neural Progenitor Cells
, Ependymal cell
, Hydrocephalus
, Neurogenesis
, Astrocyte
, Self-Renewal
, Differentiation
, Medulloblastoma
, Neural Stem Cells
, Primary cilia
, Neuroscience
Research theme for competitive and other funds (6)：
- 2024 - 2028 陽子線 FLASH 照射による難治性脳腫瘍根絶へ向けた開発
- 2024 - 2028 髄芽腫オルガノイドを用い、神経幹細胞のがん化メカニズムを解き明かす
- 2021 - 2026 疾患iPS細胞由来腎オルガノイドの樹立による新規腎結石モデルと結石溶解療法の開発
- 2021 - 2025 ヒト脳オルガノイドの樹立による、脳のしわ形成機序の解明
- 2020 - 2024 Uncover pathomechanism of megalencephaly using brain organdies.
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Papers (27)：
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Yuji Nakamura, Issei S Shimada, Reza Maroofian, Micol Falabella, Maha S Zaki, Masanori Fujimoto, Emi Sato, Hiroshi Takase, Shiho Aoki, Akihiko Miyauchi, et al. Biallelic null variants in PNPLA8 cause microcephaly by reducing the number of basal radial glia. Brain : a journal of neurology. 2024
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Issei S. Shimada, Akari Goto, Yutaka Hashimoto, Hiroshi Takase, Masayuki Itoh, Yoichi Kato. Spatial ciliary signaling regulates the dorsal/ventral regionalization of human brain organoids. 2024
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Fatma M Minisy, Hossam H Shawki, Tsubasa Fujita, Ahmed M Moustafa, Rumeysa Sener, Youske Nishio, Issei S Shimada, Shinji Saitoh, Mayumi Sugiura-Ogasawara, Hisashi Oishi. Transcription Factor 23 is an Essential Determinant of Murine Term Parturition. Molecular and cellular biology. 2024. 1-18
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Ryan Earwood, Hiromasa Ninomiya, Hao Wang, Issei Shimada, Mia Stroud, Diana Perez, Udval Uuganbayar, Chisato Yamada, Toru Akiyama-Miyoshi, Branko Stefanovic, et al. The binding of LARP6 and DNAAF6 in biomolecular condensates influences ciliogenesis of multi-ciliated cells. The Journal of biological chemistry. 2024. 107373-107373
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Tomoki Okada, Atsushi Okada, Hiromasa Aoki, Daichi Onozato, Taiki Kato, Hiroshi Takase, Shigeru Ohshima, Teruaki Sugino, Rei Unno, Kazumi Taguchi, et al. Phagocytosis model of calcium oxalate monohydrate crystals generated using human induced pluripotent stem cell-derived macrophages. Urolithiasis. 2024. 52. 1
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MISC (6)：
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嶋田 逸誠, 加藤 洋一. 再生医療にむけた脳オルガノイドの研究 : 神経幹細胞の制御メカニズムの解明-The future of neural stem cell research using human brain organoids. 細胞. 2024. 56. 9. 706-708
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嶋田 逸誠, 加藤 洋一. 脳オルガノイドを用いた神経幹細胞研究の新たな展望. BIO Clinica. 2023. 38. 11. 953-955
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岡田 朋記, 岡田 淳志, 服部 竜也, 杉野 輝明, 田口 和己, 浜本 周造, 嶋田 逸誠, 松永 民秀, 安井 孝周. 疾患iPS嚢胞を用いた尿路結石モデル腎オルガノイドの樹立. 日本腎臓学会誌. 2021. 63. 4. 504-504
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Chic Hiratani, Takehiro Kusakabe, Issei Shimada, Hideo Iwamoto, Takeo Horie, Motovuki Tsuda. Immunohistochemical and developmental analyses of adult photoreceptive organs in the ascidian Ciona intestinalis. ZOOLOGICAL SCIENCE. 2004. 21. 12. 1311-1311
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Kitajima Yuka, Shimada Issei, Horie Takeo, Kusakabe Takehiro, Tsuda Motoyuki. CHARACTERIZATION OF GONADOTROPIN-RELEASING HORMONE RECEPTORS FOUND IN THE NEURAL COMPLEX OF THE ASCIDIAN CIONA INTESTINALIS(Endocrinology,Abstracts of papers presented at the 74^<th> Annual Meeting of the Zoological Society of Japan) :. Zoological science. 2003. 20. 12. 1602-1602
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Patents (1)：
Education (3)：
- 2005 - 2010 University of Vermont, Graduate School College of Medicine Department of Anatomy and Neurobiology
- 2002 - 2004 University of Hyogo, Graduate School Department of Science Life Science
- 1998 - 2002 University of Hyogo Department of Science Life Science
Professional career (1)：
- PhD (University of Vermont)
Work history (4)：
- 2018/08 - 現在 Nagoya City University Graduate School of Medical Sciences, Department of Cell Biology Junior Associate Professor
- 2015/01 - 2018/07 University of Texas Southwestern Medical School Department of Cell Biology Assistant Instructor
- 2011/08 - 2014/12 University of Texas Southwestern Medical School Children's Research Institute Post-doc
- 2010/04 - 2011/07 University of Vermont, Graduate School Department of Medicine Post-doc
Awards (6)：
Association Membership(s) (2)：
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, 神経化学会
