Takahito Miyake

ミヤケタカヒト | Takahito Miyake

Affiliation and department：

Research field (4)： Metabolism and endocrinology , Neuroscience - general , Cell biology , Molecular biology

Research keywords (4)： Molecular Biology , Biochemistry , Neuroscience , Circadian clock

Research theme for competitive and other funds (9)：

2024 - 2028 uORFー非翻訳領域の翻訳ーが支配する生命機能の解明
2023 - 2026 神経病態薬理学基盤拡張にむけたプレシナプトロジーの創成
2022 - 2024 Mechanism of uORF-mediated biological clock phase control by physiological temperature changes
2022 - 2024 神経間シナプス接続捕捉システムが明かす「時刻」の出力回路基盤
2021 - 2022 老化に伴う体内時計の臓器間同調不全機構の解明

Show all

Papers (32)：

Takahito Miyake, Kaho Tanaka, Yutsuki Inoue, Yuji Nagai, Reo Nishimura, Takehito Seta, Shumpei Nakagawa, Ken-Ichi Inoue, Emi Hasegawa, Takafumi Minamimoto, et al. Size-reduced DREADD derivatives for AAV-assisted multimodal chemogenetic control of neuronal activity and behavior. Cell reports methods. 2024. 4. 10. 100881-100881
Yuto Fujita, Takahito Miyake, Xinyan Shao, Yuto Aoki, Emi Hasegawa, Masao Doi. Omeprazole Induces CYP3A4 mRNA Expression but Not CYP3A4 Protein Expression in HepaRG Cells. Biological and Pharmaceutical Bulletin. 2024. 47. 6. 1218-1223
Xinyan Shao, Takahito Miyake, Yuichi Inoue, Emi Hasegawa, Masao Doi. Temperature-Dependent Upregulation of Per2 Protein Expression Is Mediated by eIF2α Kinases PERK and PKR through PI3K Activation. Biological and Pharmaceutical Bulletin. 2024. 47. 3. 600-605
Kotaro Tomuro, Mari Mito, Takahito Miyake, Siu Yu A. Chow, Masao Doi, Yoshiho Ikeuchi, Yuichi Shichino, Shintaro Iwasaki. Absolute calibration of ribosome profiling assesses the dynamics of ribosomal flux on transcripts. 2023
Takahito Miyake, Yuichi Inoue, Xinyan Shao, Takehito Seta, Yuto Aoki, Khanh Tien Nguyen Pham, Yuichi Shichino, Junko Sasaki, Takehiko Sasaki, Masahito Ikawa, et al. Minimal upstream open reading frame of Per2 mediates phase fitness of the circadian clock to day/night physiological body temperature rhythm. Cell reports. 2023. 42. 3. 112157-112157

ｍore...

MISC (17)：

ｍore...

Lectures and oral presentations (33)：

The minimal upstream open reading frame of Per2 has a role in enhancing the integrity of the physiological circadian response
(2024)
Temperature entrainment mechanism of peripheral clocks via circadian body temperature and its role in physiology
(2024)
生理的微小温度変化を感知するmRNA翻訳制御エレメントの発見とその生理的意義
(第3回関西RNAクラブ 2024)
コア時計遺伝子Per2 の最小単位上流翻訳領域は生物時計の概日体温リズムへの同調に重要である
(2023年度先端モデル動物プラットフォーム成果発表会 2024)
体内時計を介した概日体温リズムによる生体恒常性維持機構
(2023年度生理学研究所研究会「臓器連関による生体恒常性維持機構と生体活動の統合的理解」 2024)

ｍore...

Education (3)：

2014 - 2017 Kyoto University Graduate School of Pharmaceutical Sciences Department of Molecular Pharmacology
2012 - 2014 Kyoto University Graduate School of Pharmaceutical Sciences Department of Molecular Pharmacology
2008 - 2012 Kyoto University Faculty of Pharmaceutical Scieonces Division of Pharmaceutical Sciences

Professional career (1)：

Work history (6)：

2018/10 - 現在 Graduate School of Pharmaceutical Sciences, Kyoto University Department of Systems Biology Assistant Professor
2018/05 - 2018/11 JSPS Overseas Research Fellowships
2017/05 - 2018/11 University of California, San Francisco Department of Physiology Postdoctoral scholar
2017/04 - 2017/04 Graduate School of Pharmaceutical Sciences, Kyoto University Department of Molecular Pharmacology Researcher
2016/04 - 2017/04 JSPS Research Fellowships for Young Scientists (DC2 --> PD)

Show all

Awards (10)：

Show all

Association Membership(s) (5)：

THE JAPAN NEUROSCIENCE SOCIETY , THE PHARMACEUTICAL SOCIETY OF JAPAN , 日本時間生物学会 , 日本分子生物学会 , 日本内分泌学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page