Takahito Miyake

ミヤケタカヒト | Takahito Miyake

Affiliation and department：

Research field (4)： Metabolism and endocrinology , Neuroscience - general , Cell biology , Molecular biology

Research keywords (4)： Molecular Biology , Biochemistry , Neuroscience , Circadian clock

Research theme for competitive and other funds (7)：

2023 - 2026 神経病態薬理学基盤拡張にむけたプレシナプトロジーの創成
2022 - 2024 Mechanism of uORF-mediated biological clock phase control by physiological temperature changes
2021 - 2022 老化に伴う体内時計の臓器間同調不全機構の解明
2021 - 2022 神経回路選別技術の新規開発に基づく「目覚め」の解明
2020 - 2022 A Novel Method for Rapid Quantification of Translation Rate Reveals the Regulation of Translation Rate in Sensory Nerve Endings

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Papers (29)：

Kotaro Tomuro, Mari Mito, Takahito Miyake, Siu Yu A. Chow, Masao Doi, Yoshiho Ikeuchi, Yuichi Shichino, Shintaro Iwasaki. Absolute calibration of ribosome profiling assesses the dynamics of ribosomal flux on transcripts. 2023
Takahito Miyake, Yuichi Inoue, Xinyan Shao, Takehito Seta, Yuto Aoki, Khanh Tien Nguyen Pham, Yuichi Shichino, Junko Sasaki, Takehiko Sasaki, Masahito Ikawa, et al. Minimal upstream open reading frame of Per2 mediates phase fitness of the circadian clock to day/night physiological body temperature rhythm. Cell reports. 2023. 42. 3. 112157-112157
Yuki Hamada, Lena Sasaki, Hikari Uehara, Tomo Suzuki, Shigeru Kinoshita, Kento Otsuka, Akio Kihara, Yoshiaki Yamaguchi, Takahito Miyake, Masao Doi. Optimising the method for visualising mouse meibomian gland using eyelid whole-mount lipid staining. The ocular surface. 2022. 26. 268-270
Lena Sasaki, Yuki Hamada, Daisuke Yarimizu, Tomo Suzuki, Hiroki Nakamura, Aya Shimada, Khanh Tien Nguyen Pham, Xinyan Shao, Koki Yamamura, Tsutomu Inatomi, et al. Intracrine activity involving NAD-dependent circadian steroidogenic activity governs age-associated meibomian gland dysfunction. Nature Aging. 2022. 2. 2. 105-114
Takahito Miyake, Masao Doi. Roles of the Circadian Clock Mechanism in the Regulation of Daily Rhythms of Body Temperature. Brain and nerve. 2022. 74. 2. 159-166

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MISC (17)：

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Lectures and oral presentations (33)：

The minimal upstream open reading frame of Per2 has a role in enhancing the integrity of the physiological circadian response
(2024)
Temperature entrainment mechanism of peripheral clocks via circadian body temperature and its role in physiology
(2024)
生理的微小温度変化を感知するmRNA翻訳制御エレメントの発見とその生理的意義
(第3回関西RNAクラブ 2024)
コア時計遺伝子Per2 の最小単位上流翻訳領域は生物時計の概日体温リズムへの同調に重要である
(2023年度先端モデル動物プラットフォーム成果発表会 2024)
体内時計を介した概日体温リズムによる生体恒常性維持機構
(2023年度生理学研究所研究会「臓器連関による生体恒常性維持機構と生体活動の統合的理解」 2024)

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Education (3)：

2014 - 2017 Kyoto University Graduate School of Pharmaceutical Sciences Department of Molecular Pharmacology
2012 - 2014 Kyoto University Graduate School of Pharmaceutical Sciences Department of Molecular Pharmacology
2008 - 2012 Kyoto University Faculty of Pharmaceutical Scieonces Division of Pharmaceutical Sciences

Professional career (1)：

Work history (6)：

2018/10 - 現在 Graduate School of Pharmaceutical Sciences, Kyoto University Department of Systems Biology Assistant Professor
2018/05 - 2018/11 JSPS Overseas Research Fellowships
2017/05 - 2018/11 University of California, San Francisco Department of Physiology Postdoctoral scholar
2017/04 - 2017/04 Graduate School of Pharmaceutical Sciences, Kyoto University Department of Molecular Pharmacology Researcher
2016/04 - 2017/04 JSPS Research Fellowships for Young Scientists (DC2 --> PD)

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Awards (9)：

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Association Membership(s) (5)：

THE JAPAN NEUROSCIENCE SOCIETY , THE PHARMACEUTICAL SOCIETY OF JAPAN , 日本時間生物学会 , 日本分子生物学会 , 日本内分泌学会

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