Umeda Kenichi

Affiliation and department：

Research field (2)： Thin-film surfaces and interfaces , Nanobioscience

Research keywords (9)：生物物理 , 電子工学 , 高速AFM , 光ピンセット , 分子動力学計算 , 原子間力顕微鏡 , 走査プローブ顕微鏡 , 表面科学 , 応用物理

Research theme for competitive and other funds (13)：

2023 - 2027 AI駆動による高速AFM計測・解析の自動化
2021 - 2024 高速AFM/光ピンセット複合機を用いたSMCの液-液相分離の形成・破壊機構の解明
2020 - 2024 高速AFM を用いたSMC 複合体の力学機構の解明
2022 - 2023 Temperature-modulated supramolecular nanomachinery for manipulating programmed cell death
2019 - 2021 高速AFM/光ピンセット複合装置を用いた生体分子の機能動態の解明

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Papers (38)：

Shin Morioka, Takumi Oishi, Suguru Hatazawa, Takahiro Kakuta, Tomoki Ogoshi, Kenichi Umeda, Noriyuki Kodera, Hitoshi Kurumizaka, Mikihiro Shibata. High-Speed Atomic Force Microscopy Reveals the Nucleosome Sliding and DNA Unwrapping/Wrapping Dynamics of Tail-less Nucleosomes. Nano Letters. 2024
Ayumi Sumino, Takashi Sumikama, Yimeng Zhao, Holger Flechsig, Kenichi Umeda, Noriyuki Kodera, Motoyuki Hattori, Mikihiro Shibata. High-speed AFM reveals fluctuations and dimer splitting of the N-terminal domain of GluA2-γ2. 2023
Kien Xuan Ngo, Huong T Vu, Kenichi Umeda, Minh-Nhat Trinh, Noriyuki Kodera, Taro Q.P. Uyeda. Deciphering the actin structure-dependent preferential cooperative binding of cofilin. bioRxiv. 2023
Shotaro Tsujioka, Ayumi Sumino, Yutaro Nagasawa, Takashi Sumikama, Holger Flechsig, Leonardo Puppulin, Takuya Tomita, Yudai Baba, Takahiro Kakuta, Tomoki Ogoshi, et al. Imaging single CaMKII holoenzymes at work by high-speed atomic force microscopy. Science advances. 2023. 9. 26. eadh1069
Takahiro Watanabe-Nakayama, Mayumi Tsuji, Kenichi Umeda, Tatsunori Oguchi, Hiroki Konno, Moeko Noguchi-Shinohara, Yuji Kiuchi, Noriyuki Kodera, David B. Teplow, Kenjiro Ono. Structural Dynamics of Amyloid-β Protofibrils and Actions of Anti-Amyloid-β Antibodies as Observed by High-Speed Atomic Force Microscopy. Nano Letters. 2023. 23. 13. 6259-6268

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Patents (5)：

Lectures and oral presentations (37)：

高速AFMを用いたSmc5/6のサブ分子スケール機能動態の解明
(令和5年度生物物理中部支部討論会 2024)
高速AFMを用いたSMCサブ分子動態計測および計測手法の更なる革新
(生物物理学セミナー, 京都大学 2024)
Development of Zero-Latency Amplitude Detector Towards Next-Generation Ultrafast High-Speed AFM
(31st International Colloquium on Scanning Probe Microscopy (ICSPM31) 2023)
High-speed AFM imaging of the cholesterol transporter ABCA1 reconstituted in lipid membrane patch
(第61回日本生物物理学会年会 2023)
Improvement of the Z-scanner system for faster high-speed AFM
(第61回日本生物物理学会年会 2023)

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Work history (6)：

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Awards (5)：

2022/09 - AFM BioMed Conference 2022 Young Investigator Award High-Speed AFM Study of Structural Maintenance of Chromosomes
2018/05 - 公益社団法人第37回表面科学学術講演会講演奨励賞(若手研究者部門) 液中動作3D-FM-AFMおよびMD計算を用いたイオン液体水溶液の溶媒和構造の解明
2012/12 - 20th International Colloquium on Scanning Probe Microscopy (ICSPM20) Poster award Quantitative charge density measurement of biomolecule in aqueous solutions by FM-AFM with force mapping technique
2010/07 - 京都大学大学院工学研究科高等研究院融合ナノ基盤工学研究部門第3回若手研究者交流会奨励賞静電励振法を用いた液中高分解能FM-AFM観察
2010/07 - 13th International Conference on Noncontact Atomic Force Microscopy Poster award High-resolution FM-AFM in liquids using electrostatic excitation method

Association Membership(s) (2)：

THE SURFACE SCIENCE SOCIETY OF JAPAN , THE JAPAN SOCIETY OF APPLIED PHYSICS

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