Kinoshita Kazuhisa

Affiliation and department：
Job title： Senior Research Scientist
Homepage URL (1)： http://www.riken.jp/chromdyna/

Research field (2)： Molecular biology , Cell biology

Research keywords (5)： chromosome , cell cycle , cell division , condensin , Xenopus laevis

Research theme for competitive and other funds (7)：

2023 - 2026 コンデンシンによる染色体構築メカニズムの総合的理解
2019 - 2023 染色体構築におけるコンデンシンIの作用機序の解明
2015 - 2019 Molecular dissection of the condensin complex by using recombinant subunits
2012 - 2016 Molecular mechanism of regulation of mitotic chromosome dynamics by condensins
2009 - 2012 Molecular mechanism of regulation of mitosis-specific chromosome dynamics

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Papers (30)：

Makoto M. Yoshida, Kazuhisa Kinoshita, Keishi Shintomi, Yuuki Aizawa, Tatsuya Hirano. Regulation of condensin II by self-suppression and release mechanisms. Molecular Biology of the Cell. 2024. 35. 2. ar21
Tetsuya Yamamoto, Kazuhisa Kinoshita, Tatsuya Hirano. Elasticity control of entangled chromosomes: crosstalk between condensin complexes and nucleosomes. Biophysical Journal. 2023. 122. 19. 3869-3881
Shoji Tane, Keishi Shintomi, Kazuhisa Kinoshita, Yuko Tsubota, Makoto M Yoshida, Tomoko Nishiyama, Tatsuya Hirano. Cell cycle-specific loading of condensin I is regulated by the N-terminal tail of its kleisin subunit. eLife. 2022. 11. e84694
Makoto M Yoshida, Kazuhisa Kinoshita, Yuuki Aizawa, Shoji Tane, Daisuke Yamashita, Keishi Shintomi, Tatsuya Hirano. Molecular dissection of condensin II-mediated chromosome assembly using in vitro assays. eLife. 2022. 11. e78984
Kazuhisa Kinoshita, Yuko Tsubota, Shoji Tane, Yuuki Aizawa, Ryota Sakata, Kozo Takeuchi, Keishi Shintomi, Tomoko Nishiyama, Tatsuya Hirano. A loop extrusion-independent mechanism contributes to condensin I-mediated chromosome shaping. JOURNAL OF CELL BIOLOGY. 2022. 221. 3. e202109016

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MISC (13)：

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Books (2)：

Lectures and oral presentations (16)：

コンデンシンによる分裂期染色体の形成機構
(高知工科大学理工学群生命情報専攻香美 2023)
A loop extrusion-independent mechanism contributes to chromosome shaping by the condensin complexes
(第61回日本生物物理学会年会シンポジウム「クロマチンとSMCタンパク質の動態から理解するゲノムモダリティ」名古屋 2023)
Chromosome axis assembly by condensins
(National Institute of Genetics, Mishima, Japan 2023)
Mitotic chromosome shaping by the condensin complexes
(Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany 2023)
A loop extrusion-independent mechanism contributes to condensin I-mediated chromosome shaping
(National Institute of Genetics, Mishima, Japan 2022)

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Professional career (1)：

Work history (9)：

2007/11 - 現在 RIKEN Chromosome Dynamics Laboratory Senior Research Scientist
2006/10 - 2007/10 Kyoto University Graduate School of Biostudies Research Scientist
2001/07 - 2006/09 Max Planck Institute of Molecular Cell Biology and Genetics Staff Scientist
2001/01 - 2001/06 Max Planck Institute of Molecular Cell Biology and Genetics Postdoctoral Fellow
1998/07 - 2001/01 European Molecular Biology Laboratory (EMBL) Postdoctoral Fellow

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Association Membership(s) (1)：

THE MOLECULAR BIOLOGY SOCIETY OF JAPAN

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