Rchr
J-GLOBAL ID：201801006455593294   Update date: Oct. 07, 2024

Goto Kyoko

Goto Kyoko
Affiliation and department：
Kanazawa University Institute of Medical,Pharmaceutical and Health SciencesFaculty of Pharmacy

About Kanazawa University Institute of Medical,Pharmaceutical and Health SciencesFaculty of Pharmacy


Other affiliations (1)：
  • ノースカロライナ大学チャペルヒル校  Adjunct Associate Professor
Research field  (1)： Pharmaceuticals - chemistry and drug development
Research theme for competitive and other funds  (18)：
  • 2019 - 2022 Chemical approaches to understand the complex mechanism of nucleotide excision repair
  • 2019 - 2022 Coffee diterpens inhibit prostate cancer progression
  • 2018 - 2022 Development of novel drug leads based on rare tropical resources
  • 2017 - 2020 The development of the innovative therapeutic drugs which targete crosstalk in the prostate cancer microenvironment
  • 2016 - 2020 Phytochemistry study of Indonesian authigenic and traditional medicinal plants
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Papers (132)：
  • Hayato Kouno, Saidanxia Amuti, Yohei Saito, Shuichi Fukuyoshi, Katsunori Miyake, Masuo Goto, David J Newman, Barry R O'Keefe, Kuo-Hsiung Lee, Kyoko Nakagawa-Goto. Isolation, Characterization, and Antiproliferative Activity of Terpenoids from the Tropical Plant Turraea delphinensis. Journal of natural products. 2024
  • Nona Koga, Yohei Saito, Katsunori Miyake, Saidanxia Amuti, Shuichi Fukuyoshi, Satoshi Yoshida, Sota Sato, Yusuke Yamada, Akihito Ikeda, Naruhiko Adachi, et al. Cyclic Sesquiterpene-Flavanone [4+2] Hybrids, Syzygioblanes A-C, Found in an Indonesian Traditional Medicine, "Jampu Salo" (Syzygium oblanceolatum). Organic letters. 2024
  • Sayaka Maeda, Wakana Nakayama, Yohei Saito, Momoko Sagano, Masuo Goto, Kyoko Nakagawa-Goto. Total Synthesis of a TNBC-Selective Cytotoxic Bromo Nor-eremophilane, PC-A, and Its Preliminary Structure-Activity Relationships. Journal of Natural Products. 2024
  • Saidanxia Amuti, Yohei Saito, Shuichi Fukuyoshi, Katsunori Miyake, David J. Newman, Barry R. O’Keefe, Kuo-Hsiung Lee, Kyoko Nakagawa-Goto. Unusual Vilasinin-Class Limonoids from Trichilia rubescens. Molecules. 2024
  • Ayano Kobayashi, Yohei Saito, Katsunori Miyake, Shuichi Fukuyoshi, David J Newman, Barry R O'Keefe, Kuo-Hsiung Lee, Kyoko Nakagawa-Goto. Caged Xanthones and Biphenyls Isolated from the Tropical Plant Garcinia lateriflora. Journal of natural products. 2024
ｍore...
MISC (3)：
Patents (8)：
  • Preparation of desmosdumotin C and B and their analogs as antitumor and anti-AIDS agents
  • 4-Aamino-2H-pyran-2-one analogs as anticancer agents and their preparation
  • Preparation of novel sesquiterpene derivatives and their use in inflammation and cancer treatment
  • Novel sesquiterpene derivatives and compositions comprising the same for treating inflammation and/or neoplasm related disorders
  • 抗がん作用を有するベンゾチオフェン誘導体
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Lectures and oral presentations  (9)：
  • Steppingstone to drug discovery with handcrafted natural products
    (The 37th Symposium on Natural Products 2022)
  • Drug Discovery and Development based on Natural Products
    (1st Makassar International Conference in Pharmaceutical Sciences 2021)
  • 薬用生理活性天然物の単離精製・合成・メディシナルケミストリーへの展開
    (日本薬学会第140年会シンポジウム "天然物パワー6.アカデミア創薬" 2020)
  • 天然物基本骨格から細胞周期阻害剤の創成
    (第129回薬学会北陸支部例会「シンポジウム」がん・免疫 -研究と臨床の最前線- 2017)
  • Drug discovery and development based on natural products
    (Special Seminar in Hasanuddin University 2017)
ｍore...
Professional career (1)：
  • 博士(薬学) (金沢大学)
Work history (9)：
  • 2024/06 - 現在 金沢大学 ナノ生命科学研究所 参画教員(兼任)
  • 2012/04 - 現在 University of North Carolina at Chapel Hill Eshelman School of Pharmacy Adjunct Associate Professor
  • 2012/04 - 現在 Kanazawa University School of Pharmaceutical Science/Pharmacy Associate Professor
  • 2011/03 - 2012/03 University of North Carolina at Chapel Hill Eshelman School of Pharmacy Research Associate Professor
  • 2006/08 - 2011/02 University of North Carolina at Chapel Hill Eshelman School of Pharmacy Research Assistant Professor
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Association Membership(s) (3)：
THE JAPANESE SOCIETY OF PHARMACOGNOSY ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  American Chemical Society
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