Makoto Nakashima

Affiliation and department：

Research field (1)： Molecular biology

Research theme for competitive and other funds (3)：

2024 - 2027 スーパーエンハンサー領域のゲノムループ構造形成によるCD30過剰発現機構の解析
2022 - 2024 CD30によるROS-DSBを介したゲノム不安定性とATL病態進展機構の解析
2019 - 2021 Analysis of ATL progression by CD30 signaling and its biomarkers

Papers (28)：

Makoto Yamagishi, Yuta Kuze, Seiichiro Kobayashi, Makoto Nakashima, Satoko Morishima, Toyotaka Kawamata, Junya Makiyama, Kako Suzuki, Masahide Seki, Kazumi Abe, et al. Mechanisms of action and resistance in histone methylation-targeted therapy. Nature. 2024
Mariko Watanabe, Hiromi Hatsuse, Kazuaki Nagao, Makoto Nakashima, Kaoru Uchimaru, Makoto Otsu, Koji Miyazaki, Ryouichi Horie. CD30 induces Reed-Sternberg cell-like morphology and chromosomal instability in classic Hodgkin lymphoma cell lines. Cancer science. 2023. 114. 8. 3433-3445
Makoto Nakashima, Kaoru Uchimaru. CD30 Expression and Its Functions during the Disease Progression of Adult T-Cell Leukemia/Lymphoma. International journal of molecular sciences. 2023. 24. 10
Makoto Nakashima, Atae Utsunomiya, Toshiki Watanabe, Ryouichi Horie, Kaoru Uchimaru. The oncogenic driving force of CD30 signaling-induced chromosomal instability in adult T-cell leukemia/lymphoma. Cancer science. 2022. 114. 4. 1556-1568
Yusaku Wada, Tomoo Sato, Hiroo Hasegawa, Takahiro Matsudaira, Naganori Nao, Ariella L G Coler-Reilly, Tomohiko Tasaka, Shunsuke Yamauchi, Tomohiro Okagawa, Haruka Momose, et al. RAISING is a high-performance method for identifying random transgene integration sites. Communications biology. 2022. 5. 1. 535-535

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MISC (8)：

岩松見, 中島誠, 村田めぐみ, 山岸誠, 手塚健太, 浜口功, 明里宏文, 内丸薫. 二次リンパ組織におけるSTLV-1感染細胞の局在とその意義. 日本HTLV-1学会学術集会. 2021. 7th
山岸誠, 鈴木穣, 窪川美雪, 久世裕太, 横溝明香里, 鈴木絢子, 小林誠一郎, 中島誠, 宇都宮與, 森島聡子, et al. 多層シングルセルプラットフォームによるクローン構造解析とTCR経路変異の生物学的意義の検討. 日本癌学会総会記事. 2020. 79回. OE7-7
Yamagishi M, Kobayashi S, Makiyama J, Araya N, Nakashima M, Iwanaga M, Utsunomiya A, Tanaka Y, Watanabe T, Yamano Y, et al. Transcriptomic and epigenomic characteristics of HTLV-1 infected cells in asymptomatic carriers, HAM/TSP, and ATLL. The 19th International conference on Human Retrovirology. 2019. 45-45
中島誠, 矢持忠徳, 渡邊真理子, 宇都宮與, 東原正明, 渡邉俊樹, 内丸薫, 堀江良一. CD30陽性HTLV-1感染細胞の特徴とブレンツキシマブベドチンの効果について(The characteristics of CD30-positive HTLV-1 infected cells and the effects of brentuximab vedotin). 臨床血液. 2018. 59. 9. 1720-1720
中島誠, 渡邊真理子, 内丸薫, 堀江良一. トロゴサイトーシスによるCD30リガンド・レセプター複合体の細胞内移行機構の解析(Trogocytosis of ligand-receptor complex and its intracellular transport in CD30 signalling). 日本癌学会総会記事. 2018. 77回. 667-667

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Professional career (1)：

博士(医科学)

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