Rchr
J-GLOBAL ID:201801006707249150   Update date: May. 31, 2022

Okamura Eiichi

Okamura Eiichi
Research field  (1): Developmental biology
Research theme for competitive and other funds  (10):
  • 2021 - 2024 新規カニクイザル発生工学技術を用いた栄養膜特異的ノックアウト法の開発
  • 2021 - 2023 トランスポゾン技術を用いた効率的な疾患モデルカニクイザル作製法の開発
  • 2021 - 2022 トランスポゾンベクターを用いたカニクイザルにおける新規遺伝子改変技術の開発とヒト疾患モデルの作製
  • 2019 - 2021 Y染色体CRISPRイメージング技術の確立と哺乳動物の雌雄産み分け
  • 2017 - 2020 性ホルモン依存性精神疾患を規定するエピゲノムコードの解明
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Papers (14):
  • Hitomi Matsuzaki, Daichi Kuramochi, Eiichi Okamura, Katsuhiko Hirakawa, Aki Ushiki, Keiji Tanimoto. Recapitulation of gametic DNA methylation and its post-fertilization maintenance with reassembled DNA elements at the mouse Igf2/H19 locus. Epigenetics & chromatin. 2020. 13. 1. 2-2
  • Yasunari Seita, Toshifumi Morimura, Naoki Watanabe, Chizuru Iwatani, Hideaki Tsuchiya, Shinichiro Nakamura, Toshiharu Suzuki, Daijiro Yanagisawa, Tomoyuki Tsukiyama, Masataka Nakaya, et al. Generation of Transgenic Cynomolgus Monkeys Overexpressing the Gene for Amyloid-β Precursor Protein. Journal of Alzheimer's disease : JAD. 2020. 75. 1. 45-60
  • Okamura E, Tam OH, Posfai E, Li L, Cockburn K, Lee CQE, Garner J, Rossant J. Esrrb function is required for proper primordial germ cell development in presomite stage mouse embryos. Developmental biology. 2019. 455. 2. 382-392
  • Tanimoto K, Matsuzaki H, Okamura E, Ushiki A, Fukamizu A, Engel JD. Transvection-like interchromosomal interaction is not observed at the transcriptional level when tested in the Rosa26 locus in mouse. PloS one. 2019. 14. 2. e0203099
  • Hitomi Matsuzaki, Eiichi Okamura, Daichi Kuramochi, Aki Ushiki, Katsuhiko Hirakawa, Akiyoshi Fukamizu, Keiji Tanimoto. Synthetic DNA fragments bearing ICR cis elements become differentially methylated and recapitulate genomic imprinting in transgenic mice. Epigenetics & Chromatin. 2018. Vol.11. No.1
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Books (3):
  • カニクイザルにおける遺伝子改変技術の現状と創薬研究への展開
    オベリスク ハムリー株式会社 2022
  • 遺伝子改変カニクイザルを用いたヒト疾患モデリング
    BIO Clinica バイオクリニカ 北陸館 2021
  • 非ヒト霊長類の1種であるカニクイザルを用いたヒト疾患モデリング
    Precision Medicine 北陸館 2020
Lectures and oral presentations  (20):
  • Development of cardiomyocyte-specific hyper-speed knockout system by using in vivo genome editing
  • Establishment of trophoblast stem cell line from cynomolgus monkey placenta
    (The 94th Annual Meeting of the Japanese Biochemical Society 2021)
  • 迅速な心筋特異的ノックアウトマウスシステムの開発
    (第94回日本生化学会大会)
  • Comparative analysis of cynomolgus monkey trophoblast stem cells established under different condition
    (The 43rd Annual Meeting of the Molecular Biology Society of Japan 2020)
  • Esrrb in extraembryonic ectoderm regulates primordial germ cell development through Bmp4 gene activation
    (ConBio2017 2017)
more...
Professional career (1):
  • Ph.D. (University of Tsukuba)
Awards (1):
  • 2013/03 - 筑波大学 大学院生命環境科学研究科 生命環境科学研究科長賞
Association Membership(s) (3):
THE JAPANESE SOCIETY OF EPIGENETICS ,  JAPANESE SOCIETY OF DEVELOPMENTAL BIOLOGISTS ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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