Research field (1)：
Bio-, chemical, and soft-matter physics
Research theme for competitive and other funds (3)：
2021 - 2024 Aggregation process of amyloid-beta peptides on a membrane on a lipid membrane studied by computer simulation
2016 - 2019 Oligomer formation of amyloid-beta studied by new constant pH simulations
2012 - 2015 Oligomerization of amyloid beta-peptides studies by computer simulations
Papers (53)：
Maho Yagi-Utsumi, Yui Kanaoka, Shogo Miyajima, Satoru G. Itoh, Katsuhiko Yanagisawa, Hisashi Okumura, Takayuki Uchihashi, Koichi Kato. Single-Molecule Kinetic Observation of Antibody Interactions with Growing Amyloid β Fibrils. Journal of the american chemical society. 2024
Daiki Fukuhara, Satoru G. Itoh, Hisashi Okumura. Inhibition of amyloid-β(16-22) aggregation by polyphenols using replica permutation with solute tempering molecular dynamics simulation. Biophysics and Physicobiology. 2023. 20. 4. n/a-n/a
Hisashi Okumura, Satoru G. Itoh, Heishun Zen, Kazuhiro Nakamura. Dissociation process of polyalanine aggregates by free electron laser irradiation. PLOS ONE. 2023. 18. 9. e0291093-e0291093
Maho Yagi-Utsumi, Satoru G. Itoh, Hisashi Okumura, Katsuhiko Yanagisawa, Koichi Kato, Katsuyuki Nishimura. The Double-Layered Structure of Amyloid-β Assemblage on GM1-Containing Membranes Catalytically Promotes Fibrillization. ACS Chemical Neuroscience. 2023. 14. 15. 2648-2657
Daiki Fukuhara, Masataka Yamauchi, Satoru G. Itoh, Hisashi Okumura. Ingenuity in performing replica permutation: How to order the state labels for improving sampling efficiency. JOURNAL OF COMPUTATIONAL CHEMISTRY. 2023. 44. 4. 534-545
伊藤 暁, 矢木 真穂, 加藤 晃一, 奥村 久士. アミロイドベータペプチドの凝集初期過程の分子シミュレーション-Molecular simulation on the early aggregation process of amyloid-β peptides. 細胞. 2023. 55. 10. 784-788
S. G. Itoh, H. Okumura. Oligomerization pathway of A beta fragments by the Hamiltonian replica-permutation method. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2017. 46. S218-S218
S. G. Itoh, H. Okumura. Oligomerization process of A beta(29-42) by Coulomb replica-permutation MD simulations. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2015. 44. S147-S147
