Research field (3):
Molecular biology
, Neuroscience - general
, Genetics
Research keywords (5):
Temperature memory
, Temperature sensation
, Neural circuit
, Cold tolerance
, C. elegans
Research theme for competitive and other funds (11):
2024 - 2027 基盤研究(C)
2024 - 2027 東レ科学技術研究助成
2023 - 2024 島津科学技術振興財団 研究開発助成
2021 - 2024 温度環境変化への応答を担う新規の温度受容体候補SRHの神経生理学的解析
2023 - 2023 光科学技術研究振興財団 研究助成
2019 - 2023 動物の低温馴化における新規全身型サーキュラー神経回路の光遺伝学解析
2021 - 2022 武田科学振興財団 ライフサイエンス研究助成
2018 - 2022 Isolation of novel temperature signaling molecules using a high-throughput system
2015 - 2018 Temperature signaling through trimeric G protein in sensoryneuron of C. elegans
2014 - 2017 温度適応メモリーの分子神経メカニズム
2007 - 2008 ヒトサイトメガロウイルスを中和するヒトモノクローナル抗体の機能解析
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Papers (29):
Okahata M, Sawada N, Nakao K, Ohta A, Kuhara A. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Scientific Reports. 2024. 14. 5401. 1-14
Ohnishi K, Sokabe T, Miura T, Tominaga M, Ohta A, Kuhara A. G protein-coupled receptor-based thermosensation determines temperature acclimatization of Caenorhabditis elegans. Nature commun. 2024. 15. 1660. 1-13
Akane Ohta, Serina Yamashiro, Atsushi Kuhara. Temperature acclimation: Temperature shift induces system conversion to cold tolerance in C. elegans. Neuroscience Research. 2023. ahead of print
Misaki Okahata, Natsumi Sawada, Kenji Nakao, Akane Ohta, Atsushi Kuhara. Anticancer drugs affect temperature signaling and epigenetic factors in the cold tolerance of Caenorhabditis elegans. Research Square. 2022. 1-27
Haruka Motomura, Makoto Ioroi, Kazutoshi Murakami, Atsushi Kuhara, Akane Ohta. Head-tail-head neural wiring underlies gut fat storage in Caenorhabditis elegans temperature acclimation. PNAS. 2022. 119. 32. 1-9
Yamashiro S, Teranishi H, Motomura H, Ohta A, Kuhara A. Regulation of intestinal fat accumulation by whole-body circular neural circuits during cold tolerance and acclimation in nematode C. elegans. Low Temperature Science. 2023. 81. 19-26