Rchr
J-GLOBAL ID:201801006828679429   Update date: Feb. 26, 2024

Uchimaru Kaoru

ウチマル カオル | Uchimaru Kaoru
Affiliation and department:
Research field  (1): Hematology and oncology
Research theme for competitive and other funds  (17):
  • 2016 - 2020 Research on risk factors for the development of ATL: Long-term cohort study of HTLV-1-infected individuals.
  • 2014 - 2017 Integrated analysis of abnormal expression profiles that define phenotype of ATL cells
  • 2011 - 2014 Oncogene addiction of ATL cells and abnormal Polycomb-miRNA-signal transduction
  • 2011 - 2012 Analysis of relationship between nuclear segmentation and gene expression using neutrophils and ATL cells
  • 2010 - 2012 Analysis of adult T-cell leukemia cells using multi-color flow cytometry can detect high risk asymptomatic HTLV-1 carriers to progress into adult T-cell leukemia.
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Papers (165):
  • Makoto Yamagishi, Yuta Kuze, Seiichiro Kobayashi, Makoto Nakashima, Satoko Morishima, Toyotaka Kawamata, Junya Makiyama, Kako Suzuki, Masahide Seki, Kazumi Abe, et al. Mechanisms of action and resistance in histone methylation-targeted therapy. Nature. 2024
  • Koji Jimbo, Makoto Yamagishi, Yutaka Suzuki, Kako Suzuki, Motoko Mizukami, Kazuaki Yokoyama, Aki Sato, Tokiko Nagamura-Inoue, Yasuhito Nannya, Kaoru Uchimaru. Progression of adult T-cell leukemia/lymphoma from smoldering to acute type due to branched subclonal evolution. EJHaem. 2023. 4. 4. 1188-1190
  • Mariko Watanabe, Hiromi Hatsuse, Kazuaki Nagao, Makoto Nakashima, Kaoru Uchimaru, Makoto Otsu, Koji Miyazaki, Ryouichi Horie. CD30 induces Reed-Sternberg cell-like morphology and chromosomal instability in classic Hodgkin lymphoma cell lines. Cancer science. 2023. 114. 8. 3433-3445
  • Hiroo Katsuya, Hideaki Nakamura, Aya Maeda, Keitaro Ishii, Toshiaki Nagaie, Haruhiko Sano, Haruna Sano, Hidekazu Itamura, Sho Okamoto, Toshihiko Ando, et al. HTLV-1 cell-free DNA in plasma as a potential biomarker in HTLV-1 carriers and adult T-cell leukemia-lymphoma. eJHaem. 2023
  • Makoto Nakashima, Kaoru Uchimaru. CD30 Expression and Its Functions during the Disease Progression of Adult T-Cell Leukemia/Lymphoma. International journal of molecular sciences. 2023. 24. 10
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MISC (126):
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Professional career (1):
  • 医学博士 (東京大学)
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