Shimada Yasuhito

シマダヤスヒト | Shimada Yasuhito

Affiliation and department：
Other affiliations (1)：

三重大学ゼブラフィッシュスクリーニングセンターセンター長

Homepage URL (1)： http://yshimada.jp/

Research field (9)： Cell biology , Molecular biology , Metabolism and endocrinology , Clinical pharmacy , Physiology , Genomics , Tumor biology , Laboratory animal science , Pharmacology

Research keywords (5)： Cancer , Diabetes , Obesity , Zebrafish , Disease model animals

Research theme for competitive and other funds (12)：

2021 - 2024 Discovery of new therapeutic target genes using diabetic nephropathy model animals
2020 - 2022 Construction of photosynthetic zebrafish
2018 - 2021 Development of a zebrafish model for diabetic nephropathy and the identification of the therapeutic target genes
2017 - 2020 Endocytosis-independent membrane fusion peptides for cancer stem cell drug delivery
2016 - 2017 Identification of therapeutic target genes and early diagnosis biomarkers of abnormal glucose tolerance using a zebrafish model(Fostering Joint International Research)

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Papers (83)：

Yasuhito Shimada, Liqing Zang, Toshinari Ishimaru, Kaoru Nishiura, Koichi Matsuda, Ryota Uchida, Hiroko Nakayama, Izumi Matsuoka, Masahiro Terasawa, Norihiro Nishimura. Lipid- and glucose-lowering effects of Rhamnan sulphate from Monostroma nitidum with altered gut microbiota in mice. Food Science & Nutrition. 2024
Liqing Zang, Kazuhiro Kagotani, Takuya Hayakawa, Takehiko Tsuji, Katsuzumi Okumura, Yasuhito Shimada, norihiro nishimura. The Hexane Extract of Citrus sphaerocarpa Ameliorates Visceral Adiposity by Regulating the PI3K/AKT/FoxO1 and AMPK/ACC Signaling Pathways in High-Fat-Diet-Induced Obese Mice. Molecules. 2023
Masahiro Terasawa, Liqing Zang, Keiichi Hiramoto, Yasuhito Shimada, Mari Mitsunaka, Ryota Uchida, Kaoru Nishiura, Koichi Matsuda, Norihiro Nishimura, Koji Suzuki. Oral Administration of Rhamnan Sulfate from Monostroma nitidum Suppresses Atherosclerosis in ApoE-Deficient Mice Fed a High-Fat Diet. Cells. 2023. 12. 22. 2666-2666
Pinal S. Bhavsar, Pravin R. Dongare, Yasuhito Shimada, Anil H. Gore. A Critical Review on Current Challenges in the Analysis of Microplastics in Food Samples. ACS Food Science & Technology. 2023
Liqing Zang, Maedeh Baharlooeian, Masahiro Terasawa, Yasuhito Shimada, Norihiro Nishimura. Beneficial effects of seaweed-derived components on metabolic syndrome via gut microbiota modulation. Frontiers in Nutrition. 2023. 10

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MISC (268)：

寺澤匡博, 寺澤匡博, 臧黎清, 島田康人, 島田康人, 平本恵一, 内田亮太, 内田亮太, 西村訓弘, 鈴木宏治. 経口投与ラムナン硫酸は高脂肪食摂取ApoE欠損マウスの動脈硬化を改善した. 日本血栓止血学会誌. 2023. 34. 2
石丸敏成, ZANG Liqing, ZANG Liqing, 中山寛子, 中山寛子, 松岡いづみ, 深田一剛, 西村訓弘, 西村訓弘, 島田康人, et al. RNA-seq analysis of cataract model zebrafish during lens recovery process. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
山田将大, ZANG Liqing, ZANG Liqing, 中山寛子, 中山寛子, 深田一剛, 深田一剛, 西村訓弘, 西村訓弘, 島田康人, et al. Exploration of natural products that promote bone formation using zebrafish. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
横田皓, ZANG Liqing, ZANG Liqing, 深田一剛, 西村訓弘, 西村訓弘, 島田康人, 島田康人, 島田康人. Discovery of natural product with anemia-improving effect using a hemorrhagic zebrafish model. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
臧黎清, 島田康人, 西村訓弘. グロビン蛋白分解物による内臓脂肪型肥満改善メカニズムの解明-Mechanism of visceral obesity improvement effects of Globin Digest. Bio clinica = バイオクリニカ. 2023. 38. 1. 84-86

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Patents (46)：

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Lectures and oral presentations (72)：

Drug screening and therapeutic target discovery in obese and diabetes model zebrafish.
(Asian Conference on Fish Models for Diseases 2023)
ヒト疾患モデルゼブラフィッシュのご紹介
(Japan Basic and Clinical Pharmacology Week 2022 2022)
線虫を用いた抗サルコペニア作用を持つ天然物の探索
(第45回日本分子生物学会年会 2022)
早期骨格筋分化メカニズムの解明
(第45回日本分子生物学会年会 2022)
2型糖尿病性腎症モデルゼブラフィッシュの構築および発症メカニズムの解明
(第45回日本分子生物学会年会 2022)

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Professional career (1)：

医学博士 (三重大学)

Work history (9)：

2017/11 - 現在 Mie Univeristy Zebrafish Research Center Director
2017/04 - 現在 Mie Univeristy Medical school Associate professor
2016/04 - 現在 Mie Univeristy Adanced Science Research Center Associate professor
2016/04 - 2017/03 Mie Univeristy Medical school Assistant professor
2014/04 - 2016/03 Leiden University Molecular and Cell Biology Researcher

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Committee career (5)：

2022 - 現在 National BioResource Project Zebrafis committee member
2020 - 現在 Asian Conference On Fish Models For Diseases Scientific advisory board member
- 現在日本心脈管作動物質学会学術評議員
- 現在日本循環薬理学会学術評議員
- 現在日本薬理学会学術評議員

Awards (3)：

2022/09 - 日本温泉科学会第75回大会優秀ポスター賞
2015/09 - Mie University Intellectual property Excellence Award
2007/11 - Japanese Association of Cardiovascular Pharmacology Young Investigator Award

Association Membership(s) (6)：

JAPANESE SOCIETY FOR CIRCULATION RESEARCH , Japanese Association of Cardiovascular Pharmacology , JAPAN MIBYOU SYSTEM ASSOCIATION , THE JAPANESE BIOCHEMICAL SOCIETY , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE JAPANESE PHARMACOLOGICAL SOCIETY

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